IP Library Granted Patent US 11,801,025
Granted Patent B2
US 11,801,025 · App. 17/869,408 · Granted Oct 31, 2023

System and method for generating and displaying tomosynthesis image slabs

Inventors: Nikolaos Gkanatsios (Danbury, CT); Haili Chui (Fremont, CA); Xiangwei Zhang (Fremont, CA)
Assignee: Hologic, Inc.
A61B6/502A61B6/025A61B6/5223G06T11/008G06T11/60G06T2207/10081G06T2207/20021G06T2207/20076G06T2207/30068G06T2210/41
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Quick Facts
Patent No.
US 11,801,025
App. No.
17/869,408
Granted
Oct 31, 2023
Kind
B2
Abstract

A system for processing breast tissue images includes an image processing computer and a user interface operatively coupled to the image processing computer, wherein the image processing computer is configured to obtain image data of breast tissue, processing the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue, process respective subsets of the reconstructed image slices to generate a set of image slabs, each image slab comprising a synthesized 2D image of a portion of the breast tissue obtained from a respective subset of the set of reconstructed image slices.

Claims (36)

1. A system for processing breast tissue images, comprising:

an image processing computer configured to:

receive image data of breast tissue:

process the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue;

determine one or more objects or regions of interest to be enhanced in a subset of the set of reconstructed image slices;

weigh each image of the subset of the set of reconstructed image slices on one of a pixel-by-pixel basis and a region-by-region basis to enhance the one or more objects or regions of interest;

generate from the subset of the set of reconstructed image slices an image slab that includes the enhanced one or more objects or regions of interest, the image slab comprising a constructed 2D image of a portion of the breast tissue, the 2D image being constructed by incorporating respective regions based on a weight of individual images of the respective regions.

2. The system of claim 1 , wherein a size of the respective regions comprises one to a plurality of pixels of the reconstructed image slices.

3. The system of claim 1 , wherein the subset of the reconstructed images used to generate the image slab comprises a predetermined number of successive reconstructed image slices.

4. The system of claim 1 , wherein the image processing computer is configured to generate a map for the synthesized 2D image that identifies the reconstructed image slices of the subset that include the one or more objects or regions of interest.

5. The system of claim 1 , wherein enhancing the one or more objects comprises highlighting the one or more objects or regions of interest in the image slab.

6. The system of claim 5 , wherein enhancing the one or more objects takes into account one or more of:

a binary map of respective highlighted objects or regions of interest;

a map of each image slice that includes a probability distribution for an identified pattern in the respective highlighted objects or regions of interest; or

importing a respective object or region of interest from an image slice of the respective subset of reconstructed image slices into the image slab, wherein the respective object or region is imported into the image slab at X, Y coordinate locations corresponding to X, Y coordinate locations of the respective object or region of interest in the image slice of the subset of the set of reconstructed image slices.

7. The system of claim 1 , wherein each of the one or more objects or regions of interest is selected from a group comprising micro-calcification clusters, round-or-lobulated masses, spiculated masses, architectural distortions, linear tissues, cysts, lymph nodes, and blood vessels.

8. A system for processing breast tissue images, comprising:

an image processing computer configured to:

receive image data of breast tissue;

process the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue;

process respective subsets of the set of reconstructed image slices to generate a corresponding set of image slabs, each image slab comprising a constructed 2D image of a respective portion of the breast tissue, the 2D image being constructed by incorporating respective regions based on a weight of individual images of the respective regions;

during the processing of at least one respective subset of the set of reconstructed image slices, weigh each image of the subset of the set of reconstructed image slices on one of a pixel-by-pixel basis and a region-by-region basis to enhance one or more objects or regions of interest in the least one respective subset of the set of reconstructed image slices; and

transmit the set of image slabs to a display device.

9. The system of claim 8 , wherein a size of the respective regions comprises one to a plurality of pixels of the reconstructed image slices.

10. The system of claim 8 , wherein the respective subset of the reconstructed images used to generate each image slab comprises a predetermined number of successive reconstructed image slices.

11. The system of claim 8 , wherein the image processing computer is configured to generate a map for a respective synthesized 2D image of each image slab, the map identifying the reconstructed image slices of the subset used to generate the respective image slab.

12. The system of claim 8 , wherein enhancing the one or more objects or regions of interest comprises highlighting the one or more objects or regions of interest in a respective image slab.

13. The system of claim 8 , wherein each object or region of interest is selected from the group comprising micro-calcification clusters, round-or-lobulated masses, spiculated masses, architectural distortions, linear tissues, cysts, lymph nodes, and blood vessels.

14. A method for processing breast tissue images, comprising:

receiving image data of breast tissue;

processing the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue; and

weighing each image of a subset of the set of reconstructed image slices on one of a pixel-by-pixel basis and a region-by-region basis to enhance the one or more objects or regions of interest and to generate an image slab comprising a synthesized 2D image of a portion of the breast tissue.

15. The method of claim 14 , wherein a size of the respective regions comprises one to a plurality of pixels of the reconstructed image slices.

16. The method of claim 14 , wherein the subset of the reconstructed images used to generate the image slab comprises a predetermined number of successive reconstructed image slices.

17. The method of claim 14 , further comprising generating a map for the synthesized 2D image that identifies the reconstructed image slices of the subset that include the one or more objects or regions of interest.

18. The method of claim 14 , wherein each object or region of interest is selected from the group comprising micro-calcification clusters, round-or-lobulated masses, spiculated masses, architectural distortions, linear tissues, cysts, lymph nodes, and blood vessels.

Assignments (3)
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 075462/0440 →
SECURITY INTEREST Recorded Oct 11, 2022
From: HOLOGIC, INC.; FAXITRON BIOPTICS, LLC; BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 061639/0513 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 20, 2022
From: GKANATSIOS, NIKOLAOS; CHUI, HAILI; ZHANG, XIANGWEI
To: HOLOGIC, INC.
Reel/Frame 060568/0529 →