Device and method for dilation of a tubular anatomical structure
Described is a method and device for dilating a tubular anatomical structure. The device and method can be useful for extracting a blood clot in an artery of a mammal by concentrically irradiating an inner wall of the occluded artery using an ultraviolet (UV) laser beam delivered by an optical fiber having an external or inverted conical tip. Dilation results from photophysical production and release of nitric oxide from the cells lining the arterial wall when UV laser light is projected as a ring beam onto the inner arterial wall. This “minimal contact persistent dilation system” prepares the artery for safer mechanical extraction by thrombectomy, owing to decrease in friction and dissolution of chemical bonding.
1. A fused silica optical fiber for carrying UV laser light, said optical fiber comprising a distal end configured as an inverted cone, wherein the inverted cone refracts the UV laser light such that the UV laser light is emitted from the distal end into water as a conical beam at an emission angle β, wherein the emission angle β, as measured from a central longitudinal axis of the optical fiber, is greater than 15° and up to 56°.
2. The optical fiber of claim 1 , wherein the emitted conical beam of UV laser light impinges onto an inner wall of a tubular anatomical structure in a ring-shaped or annular configuration.
3. The optical fiber of claim 1 , wherein the distal end is a tip coupled to and in optical communication with the optical fiber.
4. The optical fiber of claim 3 , wherein the tip coupled to the distal end of the optical fiber is diamond.