PROSTHETIC CARDIAC VALVE DEVICES, SYSTEMS, AND METHODS
A system for treating a diseased native valve in a patient, the system comprising a compressible and expandable frame structure with an expanded configuration comprising one or more anchor retaining elements disposed along one or more lateral sides of the frame structure, and one or more anchors having a free end. In one embodiment, the anchors are slidably disposed within the one or more anchor retaining elements of the frame structure and can be configured to be releasably attached to one or more proximal anchor pusher elements disposed within an inner shaft of a delivery device.
1 . A system for treating a diseased native valve in a patient, the system comprising:
a frame structure having a compressed configuration and an expanded configuration wherein the frame structure comprises one or more anchor retaining elements disposed along one or more lateral sides of the frame structure;
one or more anchor elements having a free end and configured to be slidably disposed within the one or more anchor retaining elements of the frame structure;
wherein the anchor is configured to be fully disposed within the anchor retaining elements in a delivery configuration,
wherein the anchor is configured to be at least partially external to the anchor retaining elements in a deployed configuration, and
wherein the anchor is configured to be advanced from the delivery configuration to the deployed configuration when the frame structure is in the expanded configuration adjacent the diseased native valve.
2 . The system of claim 1 , further comprising a delivery device, the delivery device comprising an outer sheath and an inner sheath extendable from the outer sheath, the inner sheath having a lumen through which proximal anchor pusher elements are threaded, wherein the proximal anchor pusher elements are connected to one or more anchors by one or more anchor releasing elements.
3 . (canceled)
4 . The system of claim 2 , wherein the outer sheath has a lumen and is configured to maintain the inner sheath in an elongated configuration when positioned within the lumen.
5 . (canceled)
6 . The system of claim 2 , wherein the inner sheath is steerable.
7 . The system of claim 2 , wherein a proximal end of the one or more anchors is detachably coupled to the one or more proximal anchor pusher elements by one or more anchor releasing elements during delivery to the native valve.
8 . The system of claim 7 , wherein the one or more anchors are configured to be elongated when disposed within the anchor retaining elements.
9 . The system of claim 8 , wherein advancement of the one or more anchor pusher elements from the lumen of the inner shaft into the anchor retaining elements actuates the one or more anchors into the deployed configuration.
10 . The system of claim 8 , wherein the one or more anchors are maintained in the elongated configuration by radial constriction from the anchor retaining elements and wherein advancement of the one or more proximal anchor pusher elements out of the lumen of the inner shaft actuates the anchor into the deployed configuration.
11 . The system of claim 8 , wherein the proximal end of the anchor is detachably coupled to the and wherein retraction of the one or more proximal anchor pusher elements away from the proximal end of the one or more anchors detaches the one or more anchors from the one or more proximal anchor pusher elements.
12 . The system of claim 2 , wherein the one or more anchors is configured to lock into the one or more anchor retaining elements after actuation of the one or more anchor releasing elements.
13 . (canceled)
14 . The system of claim 1 , wherein the frame structure is detachably coupled to the delivery device in the compressed configuration during delivery to the native valve.
15 . The system of claim 14 , wherein expansion of the frame structure to the expanded configuration detaches the frame structure from the delivery device.
16 . (canceled)
17 . The system of claim 1 , wherein the free end comprises an atraumatic tip.
18 . (canceled)
19 . (canceled)
20 . The system of claim 1 , wherein the one or more anchor elements comprise a helical wire or band.
21 . The system of claim 20 , wherein the one or more anchor elements comprise a first portion comprising the helical wire or band, and a second portion comprising a straight wire or band.
22 . (canceled)
23 . (canceled)
24 . The system of claim 1 , wherein the compressed configuration is sized and dimensioned for percutaneous insertion and the expanded configuration is sized and dimensioned for implantation in the native valve of the patient.
25 . The system of claim 1 , wherein the frame structure comprises a first and second opposite ends, the first end extending above a native valve and the second end extending below the native valve when the frame structure is anchored to the native valve.
26 . The system of claim 23 , wherein the frame structure sits below the native valve when the frame structure is anchored to the native valve.
27 . The system of claim 1 , wherein the frame structure comprises an expandable stent.
28 . The system of claim 1 , wherein the expanded configuration is a generally tubular expanded shape.
29 . The system of claim 1 , wherein the frame structure comprises an expanded outer periphery in the expanded configuration and a compressed outer periphery when subject to an external radial force in the compressed configuration, wherein the compressed outer periphery is smaller in diameter than the expanded outer periphery.
30 . (canceled)
31 . The system of claim 1 , wherein the frame structure is self-expanding.
32 .- 112 . (canceled)