Inhalation device system
The invention provides an inhalation device system for the inhalative administration of a medically active liquid in nebulized form, the system comprising an inhalation device and an exchangeable reservoir for holding the medically active liquid, wherein the inhalation device comprises—a housing having a receiving unit, the receiving unit having a connection unit adapted to releasably and fluidically connect to a connection port of the exchangeable reservoir, the receiving unit being adapted to receive and fluidically connect to the exchangeable reservoir; —a nozzle for nebulization of the medically active liquid; and —a pumping unit arranged within the housing and adapted to be fluidically connected to the reservoir (via the connection unit of the receiving unit) and to the nozzle and being adapted to convey (pressurize, pump) the medically active liquid in a downstream direction from the reservoir to the nozzle.
1 . An inhalation device system for the inhalative administration of a medically active liquid in nebulized form, the system comprising an inhalation device and an exchangeable reservoir for holding the medically active liquid, wherein the inhalation device comprises
a housing having a receiving unit, the receiving unit having a connection unit adapted to releasably and fluidically connect to a connection port of the exchangeable reservoir, the receiving unit being adapted to receive and fluidically connect to the exchangeable reservoir;
a nozzle for nebulization of the medically active liquid; and
a pumping unit arranged within the housing and adapted to be fluidically connected to the reservoir and to the nozzle and being adapted to convey the medically active liquid in a downstream direction from the reservoir to the nozzle;
wherein
the exchangeable reservoir is provided in form of a cartridge system having an overall volume V o and comprising a container portion having an effective volume V e for holding the medically active liquid and the connection port adapted to releasably and fluidically connect the cartridge system to the pumping unit, wherein the cartridge system further comprises an extension element having an additional volume Va, the extension element being attached to an outer surface of the container portion, and an inner container located within and extending through the container portion and into the extension element, the inner container comprising a collapsible bag configured to hold the medically active liquid.
2 . The inhalation device system according to claim 1 , wherein the sum of the effective volume V e of the container portion and the additional volume V a of the extension element equals the overall volume V o of the cartridge system.
3 . The inhalation device system according to claim 2 , wherein the exchangeable reservoir comprises the container portion having an effective length L e and the extension element having an additional length L a , and wherein the sum of the effective length L e of the container portion and the additional length L a of the extension element equals the overall length L o of the cartridge system in an assembled state.
4 . The inhalation device system according to claim 1 , wherein the extension element of the cartridge system is removably attached to the outer surface of the container portion.
5 . The inhalation device system according to claim 1 , wherein the extension element is attached to the outer surface of the container portion by a force- or form-fit connection.
6 . The inhalation device system according to claim 1 , wherein the extension element has substantially the same cross-sectional diameter as the container portion of the cartridge system.
7 . The inhalation device system according to claim 1 , wherein the extension element of the cartridge system is a hollow body without functional elements contained therein.
8 . The inhalation device system according to claim 1 , wherein the extension element comprises a functional element contained within an inner lumen of the extension element.
9 . The inhalation device system according to claim 1 , wherein the extension element of the cartridge system does not comprise an indicator device for counting the number of uses of the inhalation device or exchangeable reservoir.
10 . The inhalation device system according to claim 1 , wherein the pumping unit of the inhalation device comprises
an upstream end that is fluidically connected to the exchangeable reservoir;
a downstream end that is fluidically connected to the nozzle;
wherein the pumping unit further comprises
(i) a riser pipe having an upstream end, wherein the riser pipe is
adapted to function as a piston in the pumping unit, and
firmly affixed to a user-facing side of the housing such as to be immobile relative to the housing; and
(ii) a hollow cylinder located upstream of the riser pipe, wherein the upstream end of the riser pipe is inserted in the cylinder such that the cylinder is longitudinally movable on the riser pipe.
11 . An inhalation device system for the inhalative administration of a medically active liquid in nebulized form, the system comprising an inhalation device and an exchangeable reservoir for holding the medically active liquid,
wherein the inhalation device comprises:
a housing having a receiving unit, the receiving unit having a connection unit configured to releasably and fluidically connect to a connection port of the exchangeable reservoir;
a nozzle for nebulization of the medically active liquid; and
a pumping unit arranged within the housing and configured to be fluidically connected to the exchangeable reservoir and to the nozzle and being configured to convey the medically active liquid in a downstream direction from the exchangeable reservoir to the nozzle;
wherein
the exchangeable reservoir is provided as a cartridge system, the cartridge system comprising:
a container portion having an effective volume V e for holding the medically active liquid,
an extension element having an additional volume V a , the extension element being attached to the outer surface of the container portion, and
an inner container located within and extending through the container portion and into the extension element, the inner container comprising a collapsible bag configured to hold the medically active liquid and having a maximum volume V i in a range from about 7.0 mL to 8.0 mL;
the container portion comprising the connection port configured to releasably and fluidically connect the exchangeable reservoir to the pumping unit; and
the sum of the effective volume V e of the container portion and the additional volume V a of the extension element equals an overall volume V o of the cartridge system.
12 . The inhalation device system according to claim 11 , wherein the extension element of the cartridge system is permanently attached to the outer surface of the container portion.
13 . The inhalation device system according to claim 11 , wherein the container portion and the extension element are made of the same material.
14 . The inhalation device system according to claim 11 , wherein the extension element has substantially a same cross-sectional diameter as the container portion of the cartridge system.
15 . The inhalation device system according to claim 11 , wherein the extension element has a differing cross-sectional diameter to the container portion of the cartridge system.
16 . The inhalation device system according to claim 11 , wherein the inhalation device further comprises an outlet valve.
17 . The inhalation device system according to claim 11 , wherein the inhalation device further comprises an inlet valve.
18 . The inhalation device system according to claim 11 , wherein the pumping unit of the inhalation device comprises:
an upstream end that is fluidically connected to the exchangeable reservoir;
a downstream end that is fluidically connected to the nozzle; wherein the pumping unit further comprises:
(i) a riser pipe having an upstream end, wherein the riser pipe is
configured as a piston in the pumping unit, and
firmly affixed to a user-facing side of the housing and is immobile relative to the housing; and
(ii) a hollow cylinder located upstream of the riser pipe, wherein the upstream end of the riser pipe is inserted in the cylinder with the cylinder longitudinally movable on the riser pipe.