IP Library Granted Patent US 12,295,771
Granted Patent B2
US 12,295,771 · App. 17/910,311 · Granted May 13, 2025

Systems and methods for measuring deflection of foam breast compression paddle

Inventors: Baorui Ren (Marlborough, MA); Kenneth Defreitas (Marlborough, MA); Alan Rego (Marlborough, MA); Christopher Ruth (Marlborough, MA); Andrew P. Smith (Marlborough, MA); Zhenxue Jing (Marlborough, MA); Jay A. Stein (Marlborough, MA)
Assignee: Hologic, Inc.
A61B6/502A61B6/025A61B6/0414A61B6/463A61B6/5217A61B6/5252A61B6/544A61B90/39A61B6/488A61B2090/3966
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Quick Facts
Patent No.
US 12,295,771
App. No.
17/910,311
Granted
May 13, 2025
Kind
B2
Abstract

A method of imaging a breast compressed with a foam paddle includes emitting an x-ray energy from an x-ray source towards the breast and the foam paddle having a plurality of upper markers and a plurality of lower markers, wherein the plurality of lower markers are movable relative to the upper markers. The x-ray energy is detected at a detector disposed opposite the breast from the x-ray source. An image of the compressed breast is generated based on the detected x-ray energy. At least one of the plurality of upper markers and at least one of the plurality of lower markers is identified in the image. A thickness of the compressed breast at a plurality of thickness locations is determined, wherein each of the plurality of thickness locations corresponds to at least one of the plurality of lower markers.

Claims (41)

1. A method of imaging a breast compressed with a foam paddle, the method comprising:

emitting an x-ray energy from an x-ray source towards the breast and the foam paddle having a plurality of upper markers and a plurality of lower markers, wherein the plurality of lower markers are movable relative to the plurality of upper markers;

detecting the x-ray energy at a detector disposed opposite the breast from the x-ray source;

generating an image of the compressed breast based on the detected x-ray energy;

identifying, in the image, at least one of the plurality of upper markers and at least one of the plurality of lower markers; and

determining a thickness of the compressed breast at a plurality of thickness locations, wherein each of the plurality of thickness locations corresponds to at least one of the plurality of lower markers.

2. The method of claim 1 , wherein determining the thickness comprises calculating a distance, in the image, between a first upper marker of the plurality of upper markers and an image-adjacent first lower marker of the plurality of lower markers.

3. The method of claim 1 , wherein determining the thickness comprises determining a characteristic, in the image, of at least one lower marker of the plurality of lower markers.

4. The method of claim 1 , wherein determining the thickness comprises calculating a distance, in the image, between a first upper marker of the plurality of upper markers and a second upper marker of the plurality of upper markers.

5. The method of claim 1 , wherein determining the thickness comprises calculating a distance, in the image, between a first lower marker of the plurality of lower markers and a second lower marker of the plurality of lower markers.

6. The method of claim 1 , wherein the x-ray energy comprises a scout exposure.

7. The method of claim 6 , further comprising calculating an automatic exposure control based at least in part on the determination of the thickness.

8. The method of claim 7 , further comprising emitting an imaging x-ray energy based at least in part on the calculated automatic exposure control.

9. The method of claim 1 , further comprising:

modeling a difference in at least two thickness locations of the plurality of thickness locations; and

applying attenuation to the image based at least in part of the modeled difference.

10. The method of claim 1 , further comprising:

performing a tomosynthesis imaging procedure;

obtaining a set of tomosynthesis images of the compressed breast from the tomosynthesis imaging procedure; and

identifying a breast boundary in at least one tomosynthesis image of the set of tomosynthesis images.

11. The method of claim 10 , wherein identifying the breast boundary is based at least in part on the determination of the thickness.

12. The method of claim 11 , further comprising:

displaying at least one tomosynthesis image of the set of tomosynthesis images; and

displaying, on the displayed at least one tomosynthesis image of the set of tomosynthesis images, a feature indicative of the breast boundary.

13. The method of claim 12 , wherein the displayed at least one tomosynthesis image comprises an uppermost tomosynthesis image of the breast.

14. The method of claim 1 , further comprising calculating an x-ray imaging dose based at least in part on the determination of the thickness.

15. The method of claim 1 , further comprising:

processing the image;

identifying at least one reference marker of at least one of the plurality of upper markers and the plurality of lower markers;

applying a negative signal to the identified reference marker, wherein the application results in a corrected image; and

displaying the corrected image.

16. The method of claim 15 , wherein applying the negative signal comprises adjusting a pixel count at the identified reference marker.

17. A paddle for compressing a breast, the paddle comprising:

a foam profile comprising an upper surface, a lower surface, and a front wall;

a plurality of upper markers disposed proximate the upper surface, wherein the plurality of upper markers are disposed a first distance from the front wall; and

a plurality of lower markers disposed proximate the lower surface, wherein the plurality of lower markers are disposed a second distance from the front wall, the second distance configured relative to the first distance such that movement of one or more of the plurality of lower markers is measurable relative to the plurality of upper markers.

18. The paddle of claim 17 , further comprising a rigid substrate, wherein the foam profile is secured to the rigid substrate at the upper surface, and wherein the plurality of upper markers are disposed between the rigid substrate and the foam profile.

19. The paddle of claim 17 , wherein the plurality of lower markers are disposed within the foam profile.

20. The paddle of claim 17 , wherein the plurality of lower markers are configured to move when the lower surface of the paddle is acted upon by an upward force.

21. The paddle of claim 20 , wherein the plurality of upper markers are configured to remain stationary when the lower surface of the paddle is acted upon by the upward force.

22. The paddle of claim 17 , further comprising a bottom foam profile secured to the foam profile, wherein the plurality of lower markers are disposed between the bottom foam profile and the foam profile.

Assignments (4)
RELEASE OF SECURITY INTEREST RECORDED AT REEL/FRAME 061639/0513 Recorded Apr 24, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: HOLOGIC, INC.; GEN-PROBE INCORPORATED; FAXITRON BIOPTICS, LLC; BIOTHERANOSTICS, INC.
Reel/Frame 075457/0268 →
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 075462/0440 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 12, 2022
From: REN, BAORUI; DEFREITAS, KENNETH; REGO, ALAN; RUTH, CHRISTOPHER; SMITH, ANDREW P.; JING, ZHENXUE; STEIN, JAY A.
To: HOLOGIC, INC.
Reel/Frame 062051/0311 →
SECURITY INTEREST Recorded Oct 11, 2022
From: HOLOGIC, INC.; FAXITRON BIOPTICS, LLC; BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 061639/0513 →
Continuity (2)
Provisional Application 63000790 · Mar 27, 2020
Related Publication 20230121488A1 · Apr 20, 2023
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