Textured medical textiles
Described herein are implants (e.g., medical textiles/biotextiles) that include stitched gripping filaments to increase gripping, and methods of forming and using them. In some configurations these apparatuses may be configured as surgical grafts that may be used for soft tissue reconstruction, regeneration, or repair.
1. A method of making an implant having a plurality of gripping strands that enhance the gripping strength of the implant, the method comprising:
stitching a first pattern into one or more sheets of a substrate material over a mask that is positioned adjacent to a first side of the one or more sheets of the substrate material, wherein the first pattern comprises a continuous first strand of material extending adjacent to a second side of the one or more sheets of the substrate material and a second strand of material extending adjacent to the mask; and
cutting the second strand of material to release the mask from the one or more sheets of the substrate material and to form a plurality of gripping strands extending proud of the first side of the one or more sheets of the substrate material, wherein each gripping strand of the plurality of gripping strands comprises one or more arms extending from a vertex in which the gripping strand is wrapped around the continuous first strand of material extending adjacent to the second side of the one or more sheets of the substrate material.
2. The method of claim 1 , further comprising stitching a first compliance control pattern into the one or more sheets of the substrate material.
3. The method of claim 2 , wherein stitching the first compliance control pattern comprises stitching a grid pattern.
4. The method of claim 2 , wherein the first compliance control pattern is stitched before stitching the first pattern.
5. The method of claim 2 , wherein the first compliance control pattern and the plurality of gripping strands are arranged and configured so that the implant has a peak compliance strain at a load of 16 Newtons per centimeter (N/cm) that is between 10% and 30%.
6. The method of claim 1 , wherein stitching the first pattern into the one or more sheets of the substrate material comprises stitching the first pattern into one or more sheets of extracellular material (ECM).
7. The method of claim 1 , further comprising forming an anchor at an end of each arm of the one or more arms that is opposite from the vertex, wherein the anchor is formed when cutting the second strand of material.
8. The method of claim 1 , wherein the mask comprises a mesh.
9. The method of claim 1 , wherein cutting the second strand of material comprises cutting the second strand of material so that each of the one or more arms of each gripping stand is between 3 mm and 0.1 mm long.
10. The method of claim 1 , wherein stitching the first pattern comprises stitching the first and second strands of material to form a density of gripping strands between 5-50 gripping strands per cm 2 .
11. The method of claim 1 , wherein the plurality of gripping strands are formed of a resorbable material.
12. A method of forming an implant comprising a plurality of gripping strands extending proud of a first side of the implant to increase a gripping strength of the first side, the method comprising:
stitching a first grid pattern into one or more sheets of extracellular material (ECM);
stitching a back-and-forth pattern into the one or more sheets of ECM over a mask on the first side of the ECM, wherein the back-and-forth pattern comprises a continuous first strand of material extending adjacent to a second side of the ECM and a continuous second strand of material extending adjacent to the first side of the ECM;
cutting the continuous second strand of material to remove the mask and form a plurality of gripping strands extending proud of the first side of the ECM, wherein each gripping strand of the plurality of gripping strands comprises one or more arms extending from a vertex that is wrapped around the continuous first strand of material extending on the second side of the ECM; and
forming an anchor at an end of each of the one or more arms opposite from the vertex.
13. The method of claim 12 , wherein the first grid pattern is stitched before the back-and-forth pattern.
14. The method of claim 12 , wherein the first grid pattern is stitched after cutting the continuous second strand of material.
15. The method of claim 12 , wherein the anchor is formed by heating the end of each arm of the one or more arms.
16. The method of claim 12 , wherein the anchor is formed when cutting the continuous second strand of material.
17. The method of claim 12 , wherein forming the anchor comprises forming a knob-shape at the end of each arm of the one or more arms.
18. The method of claim 12 , wherein the plurality of gripping strands comprises a plurality of V-shaped griping strands.
19. The method of claim 12 , wherein each of the one or more arms of each gripping stand comprises a tilt angle relative to the second side of the ECM that is between about 80 and about 50 degrees.
20. The method of claim 12 , wherein the sheet of ECM comprises collagen.
21. The method of claim 12 , wherein the one or more sheets of ECM is a first one or more sheets of ECM, wherein the implant further comprises a second one or more sheets of ECM layered onto the first one or more sheets of ECM, wherein the first grid pattern and the back-and-forth pattern are stitched through both the first and second one or more sheets of ECM.
22. The method of claim 12 , wherein the plurality of gripping strands are arranged and configured so that the gripping strength of the implant is greater than at least twice a gripping strength of the sheet of ECM without the plurality of gripping strands.