IP Library Granted Patent US 11,813,615
Granted Patent B2
US 11,813,615 · App. 17/963,377 · Granted Nov 14, 2023

Flow cell receiver and devices

Inventors: Sandor Kovacs (Middletown, DE); David Baranson (Encinitas, CA); Eli N. Glezer (Del Mar, CA)
Assignee: Singular Genomics Systems, Inc.
B01L9/527B01L2200/025B01L2200/027B01L2300/168B01L2300/18
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Quick Facts
Patent No.
US 11,813,615
App. No.
17/963,377
Granted
Nov 14, 2023
Kind
B2
Abstract

The present disclosure relates to a flow cell receiver. The flow cell receiver can include at least one platen, having a plurality of ports. The flow cell receiver can include magnets. The flow cell receiver can be configured to automatically align, secure, and retain a flow cell carrier containing a flow cell.

Claims (27)

1. A microfluidic device comprising a flow cell receiver, wherein said flow cell receiver comprises:

a magnet; and

a platform comprising:

a vacuum port,

an input port, and

an output port; and

wherein the vacuum port and the magnet of the flow cell receiver are configured to align, secure, and retain a flow cell.

2. The microfluidic device of claim 1 , wherein the vacuum port is configured to provide sufficient vacuum pressure to ensure maximum physical contact between the flow cell and the platform.

3. The microfluidic device of claim 1 , wherein the magnet is oriented to affect constructive interference.

4. The microfluidic device of claim 1 , wherein the vacuum port and the magnet prevents significant movement of the flow cell.

5. The microfluidic device of claim 1 , wherein the platform-further comprises a visible light absorbing coating, or an ultraviolet light absorbing coating, or an infrared light absorbing coating, or a combination of any of the foregoing.

6. The microfluidic device of claim 1 , wherein the platform further comprises an anti-reflective coating.

7. The microfluidic device of claim 1 , further comprising a thermoelectric heating element configured to modulate temperature of the platform.

8. The microfluidic device of claim 7 , wherein said thermoelectric heating element is a Peltier device.

9. The microfluidic device of claim 1 , further comprising an optical lens.

10. The microfluidic device of claim 9 , wherein said vacuum port is not exposed to said optical lens.

11. The microfluidic device of claim 1 , wherein said flow cell receiver comprises a plurality of vacuum ports.

12. The microfluidic device of claim 9 , wherein said flow cell receiver comprises a plurality of vacuum ports.

13. The microfluidic device of claim 12 , wherein said vacuum ports are not exposed to said optical lens.

14. The microfluidic device of claim 1 , further comprising a fluidic system in fluidic communication with the input port and the output port of said platform.

15. The microfluidic device of claim 2 , wherein the vacuum pressure is about 760 torr to about 500 torr.

16. The microfluidic device of claim 1 , wherein said platform comprises stainless steel or aluminum.

17. The microfluidic device of claim 1 , further comprising a heat sink and a fan.

18. The microfluidic device of claim 1 , wherein said flow cell receiver comprises a circuit board.

19. The microfluidic device of claim 18 , wherein said circuit board is configured to contact an electronically erasable programmable read only memory (EEPROM) chip.

20. The microfluidic device of claim 18 , wherein said circuit board is configured for storing and processing information, and/or modulating and demodulating a radio-frequency (RF) signal.

21. The microfluidic device of claim 1 , wherein the vacuum port and the magnet of the flow cell receiver are configured to align, secure, and retain a flow cell carrier containing the flow cell.

Assignments (2)
SECURITY INTEREST Recorded Mar 7, 2025
From: SINGULAR GENOMICS SYSTEMS, INC.
To: FIRST-CITIZENS BANK & TRUST COMPANY
Reel/Frame 070440/0465 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 11, 2022
From: KOVACS, SANDOR; BARANSON, DAVID; GLEZER, ELI N.
To: SINGULAR GENOMICS SYSTEMS, INC
Reel/Frame 061743/0888 →
Continuity (3)
Continuation 17105337 · Nov 25, 2020
Provisional Application 62952790 · Dec 23, 2019
Related Publication 20230070067A1 · Mar 9, 2023