IP Library Granted Patent US 12,708,619
Granted Patent B2
US 12,708,619 · App. 17/967,415 · Granted Aug 18, 2026

Use of pridopidine for treating anxiety and depression

Inventors: Michael Hayden (Yakum, IL); Michal Geva (Even-Yehuda, IL)
Assignee: Prilenia Neurotherapeutics Ltd.
A61K31/451A61P25/00A61P25/22A61P25/24
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Quick Facts
Patent No.
US 12,708,619
App. No.
17/967,415
Granted
Aug 18, 2026
Kind
B2
Abstract

This invention provides a method of treating depression or anxiety in a human subject by administering a composition comprising pridopidine or a pharmaceutically acceptable salt thereof.

Claims (12)

1 . A method of treating depression or anxiety in a human subject by administering a composition comprising an amount of pridopidine, or a pharmaceutically acceptable salt thereof.

2 . The method of claim 1 , wherein the depression or anxiety is not caused by Huntington's Disease.

3 . The method of claim 1 , wherein the depression or anxiety is associated with cognitive deficits.

4 . The method of claim 2 , wherein the depression or anxiety is associated with cognitive deficits.

5 . The method of claim 3 , wherein the cognitive deficits comprise memory loss, loss of higher reasoning, forgetfulness, learning disabilities, concentration difficulties, or decreased intelligence.

6 . The method of claim 4 , wherein the cognitive deficits comprise memory loss, loss of higher reasoning, forgetfulness, learning disabilities, concentration difficulties, or decreased intelligence.

7 . The method of claim 1 , wherein the composition comprises between 22.5 mg/day and 315 mg/day of pridopidine or pharmaceutically acceptable salt thereof.

8 . The method of claim 1 , wherein the composition is administered once daily or twice daily.

9 . The method of claim 1 , wherein the composition is administered orally.

10 . The method of claim 1 , wherein the pharmaceutically acceptable salt of pridopidine comprises pridopidine hydrochloride, hydrobromide, nitrate, perchlorate, phosphate, sulphate, formate, acetate, aconate, ascorbate, benzenesulphonate, benzoate, cinnamate, citrate, embonate, enantate, fumarate, glutamate, glycolate, lactate, maleate, malonate, mandelate, methanesulphonate, naphthalene-2-sulphonate, phthalate, salicylate, sorbate, stearate, succinate, tartrate or toluene-p-sulphonate salt.

11 . The method of claim 10 , wherein the salt comprises hydrochloride salt.

12 . The method of claim 1 , wherein the composition comprises an amount of pridopidine base.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 30, 2022
From: HAYDEN, MICHAEL; GEVA, MICHAL
To: PRILENIA NEUROTHERAPEUTICS LTD.
Reel/Frame 061915/0115 →
Continuity (7)
Continuation In Part 16591875 · Oct 3, 2019
Continuation In Part 15052368 · Feb 24, 2016
Continuation In Part PCTIL2022051082 · Oct 11, 2022
Continuation In Part 17498075 · Oct 11, 2021
Provisional Application 62186221 · Jun 29, 2015
Provisional Application 62120771 · Feb 25, 2015
Related Publication 20230112948A1 · Apr 13, 2023
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