IP Library Granted Patent US 12,548,173
Granted Patent B2
US 12,548,173 · App. 18/018,248 · Granted Feb 10, 2026

Combining angiographic information with fluoroscopic images

Inventors: Martin Adamski (Munich, DE); Ferdinand Storch (Munich, DE)
Assignee: Brainlab SE
G06T7/30G06T7/0014G06T7/38G06T2207/10121G06T2207/20221G06T2207/30101
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Quick Facts
Patent No.
US 12,548,173
App. No.
18/018,248
Granted
Feb 10, 2026
Kind
B2
Abstract

According to the present invention, one or more image pairs, each consisting of a fluoroscopic image and an angiographic image taken from the same position and the same viewing direction onto the patient and each being a non-stitched image, are acquired. A live fluoroscopic image is registered individually with the fluoroscopic image within the at least one of the one or more image pairs, such that the spatial relationship between the live fluoroscopic image and the at least one fluoroscopic image, and thus with the one or more angiographic images and the one or more image pairs in general, becomes known. Angiographic information representing the vascular structure can then be taken from those parts of the angiographic images within the one or more image pairs which overlap with the live fluoroscopic image and be overlayed over the live fluoroscopic image.

Claims (39)

1 . A method of overlaying angiographic information over a fluoroscopic image of a patient, the method comprising:

acquiring one or more image pair data, each image pair data representing an image pair and comprising fluoroscopic image data and angiographic image data representing a fluoroscopic image and an angiographic image, respectively, of a part of the patient, the fluoroscopic image and the angiographic image of an image pair being taken from the same position and the same viewing direction onto the patient and each being a non-stitched image,

acquiring live fluoroscopic image data representing a live fluoroscopic image of the patient,

registering the live fluoroscopic image data with the fluoroscopic image data of at least one of the one or more image pairs, thus obtaining a spatial orientation between the live fluoroscopic image and the image pair,

determining angiographic overlay image data from the angiographic image data based on the spatial orientation between the live fluoroscopic image and the at least one of the one or more image pairs, and

overlaying the angiographic overlay image data over the live fluoroscopic image.

2 . The method of claim 1 , wherein the step of acquiring one or more image pair data involves acquiring two or more image pair data.

3 . The method of claim 2 , further comprising the steps of:

calculating a set of image pair registration data, each image pair registration data representing the spatial orientation between two overlapping image pairs; and

calculating angiographic panoramic image data from the angiographic image data of the image pairs based on the set of image pair registration data,

wherein determining the angiographic overlay image data involves selecting a part of the angiographic panoramic image data.

4 . The method of claim 3 , wherein the step of calculating the angiographic panoramic image data involves stitching the angiographic image data, wherein overlapping parts of angiographic image data are combined using an arithmetic technique.

5 . The method of claim 3 , wherein calculating the angiographic panoramic image data is further based on additional registration data representing the spatial orientations between an additional fluoroscopic image and two image pairs with which the additional fluoroscopic image overlaps.

6 . The method of claims 3 , further comprising the step of dividing the two or more image pair data into two or more groups of image pair data, wherein each group of image pair data comprises image pair data that can be combined into an angiographic panorama, and wherein the steps of calculating a set of image pair registration data and of calculating angiographic panoramic image data is performed for each group of image pair data.

7 . The method of claim 2 , wherein, when the live fluoroscopic image overlaps more than one fluoroscopic image of the image pairs, the method further comprises the step of determining overlapped area data representing overlapped areas of the angiographic images-corresponding to those areas of the fluoroscopic images which are overlapped by the live fluoroscopic image and the step of determining the angiographic overlay image data uses the angiographic image data in the overlapped areas.

8 . The method of claim 2 , wherein registering the live fluoroscopic image data with the fluoroscopic image data involves registering the live fluoroscopic image with the fluoroscopic images represented by each one of the two or more image pair data.

9 . The method of claim 2 , wherein registering the live fluoroscopic image data with the fluoroscopic image data involves sequentially registering the live fluoroscopic image with the fluoroscopic images represented by the two or more image pair data until an image pair is found for which the overlap with the live fluoroscopic image is larger than a predetermined threshold.

10 . The method of claim 2 , wherein registering the live fluoroscopic image data with the fluoroscopic image data involves sequentially registering the live fluoroscopic image with the fluoroscopic images represented by the two or more image pair data until an image pair is found which overlaps with all of a predetermined partial area of the live fluoroscopic image.

11 . The method of claim 1 , further comprising the steps of:

determining bone outline data representing a contour of a bony structure in the fluoroscopic image of at least one of the at least one image pair data, and

overlaying the bone outline data corresponding to exactly one image pair data over the live fluoroscopic image.

12 . The method of claim 1 , wherein the steps of acquiring live fluoroscopic image data and overlaying the angiographic overlay image data are repeated sequentially over time.

13 . The method of claim 12 , wherein a repetition of the steps of registering the live fluoroscopic image data with the fluoroscopic image data and of determining angiographic overlay image data is initiated by a trigger.

14 . A non-transitory computer readable medium comprising instructions which, when executed by at least one processor, causes the at least one processor to:

acquire one or more image pair data, each image pair data representing an image pair and comprising fluoroscopic image data and angiographic image data representing a fluoroscopic image and an angiographic image, respectively, of a part of a patient, the fluoroscopic image and the angiographic image of an image pair being taken from the same position and the same viewing direction onto the patient and each being a non-stitched image,

acquire live fluoroscopic image data representing a live fluoroscopic image of the patient,

register the live fluoroscopic image data with the fluoroscopic image data of at least one of the one or more image pairs, thus obtaining a spatial orientation between the live fluoroscopic image and the image pair,

determine angiographic overlay image data from the angiographic image data based on the spatial orientation between the live fluoroscopic image and the at least one or more image pairs, and

overlay the angiographic overlay image data over the live fluoroscopic image.

15 . A medical system, comprising:

at least one processor operable to execute instructions, the instructions causing the at least one processor to:

acquire one or more image pair data, each image pair data representing an image pair and comprising fluoroscopic image data and angiographic image data representing a fluoroscopic image and an angiographic image, respectively, of a part of a patient, the fluoroscopic image and the angiographic image of an image pair being taken from the same position and the same viewing direction onto the patient and each being a non-stitched image,

acquire live fluoroscopic image data representing a live fluoroscopic image of the patient,

register the live fluoroscopic image data with the fluoroscopic image data of at least one of the one or more image pairs, thus obtaining a spatial orientation between the live fluoroscopic image and the image pair,

determine angiographic overlay image data from the angiographic image data based on the spatial orientation between the live fluoroscopic image and the at least on of the one or more image pairs, and

overlay the angiographic overlay image data over the live fluoroscopic image;

and

a medical imaging system.

16 . The system of claim 15 wherein the at least one processor is further operable to overlay angiographic information over a fluoroscopic image of a patient.

Assignments (2)
CHANGE OF NAME Recorded Dec 3, 2025
From: BRAINLAB AG
To: BRAINLAB SE
Reel/Frame 073827/0005 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 1, 2023
From: ADAMSKI, MARTIN; STORCH, FERDINAND
To: BRAINLAB AG
Reel/Frame 063827/0676 →
Priority Claims (1)
WO PCT/EP2021/059573 · Apr 13, 2021 · international
Continuity (1)
Related Publication 20230298186A1 · Sep 21, 2023
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