Patent Application
Utility
PCT National Stage
App. No. 18/044,401
· Confirmation No. 6647
IRNA COMPOSITIONS AND METHODS FOR SILENCING GROWTH FACTOR RECEPTOR BOUND PROTEIN 10 (GRB10) OR GROWTH FACTOR RECEPTOR BOUND PROTEIN 14 (GRB14) IN THE LIVER
Applicant:
ALNYLAM PHARMACEUTICALS, INC.
Notice of Allowance Mailed -- Application Received in Office of Publications
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| 2026-07-07 | NOA |
Notice of Allowance and Fees Due (PTOL-85) | 12 | View | |
| 2026-07-07 | EXIN |
Examiner Interview Summary Record (PTOL - 413) | 1 | View | |
| 2026-07-07 | IIFW |
Issue Information including classification, examiner, name, claim, renumbering, etc. | 3 | View | |
| 2026-07-07 | SRFW |
Search information including classification, databases and other search related notes | 4 | View | |
| 2026-07-07 | SRNT |
Examiner's search strategy and results | 36 | View | |
| 2026-07-07 | OA.APPENDIX |
Office Action Appendix | 7 | View | |
| 2026-07-07 | OA.APPENDIX |
Office Action Appendix | 7 | View | |
| 2026-07-07 | BIB |
Bibliographic Data Sheet | 2 | View | |
| 2026-07-07 | SRNT |
Examiner's search strategy and results | 1 | View | |
| 2026-06-24 | ECOMM.AUTH |
Internet Communications Authorization | — | View | |
| 2026-06-24 | N417 |
Electronic Filing System Acknowledgment Receipt | — | View | |
| 2026-05-15 | WFEE |
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| 2026-05-11 | CLM |
Claims | — | View | |
| 2026-05-11 | REM |
Applicant Arguments/Remarks Made in an Amendment | — | View | |
| 2026-05-11 | N417 |
Electronic Filing System Acknowledgment Receipt | — | View | |
| 2026-02-11 | CTNF |
Non-Final Rejection | 26 | View | |
| 2026-02-11 | 892 |
List of references cited by examiner | 1 | View | |
| 2026-02-11 | SRFW |
Search information including classification, databases and other search related notes | 1 | View | |
| 2026-02-11 | 1449 |
List of References cited by applicant and considered by examiner | 5 | View | |
| 2026-02-11 | BIB |
Bibliographic Data Sheet | 2 | View | |
| 2026-02-11 | 1449 |
List of References cited by applicant and considered by examiner | 5 | View | |
| 2026-02-11 | SRNT |
Examiner's search strategy and results | 30 | View | |
| 2026-02-11 | SRNT |
Examiner's search strategy and results | 1 | View | |
| 2026-02-11 | 1449 |
List of References cited by applicant and considered by examiner | 1 | View | |
| 2026-02-11 | FOR |
Foreign Reference | 255 | View | |
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List of References cited by applicant and considered by examiner | 31 | View | |
| 2026-01-09 | ELC. |
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| 2026-01-09 | ELC. |
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| 2026-01-09 | SPEC |
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| 2026-01-09 | CLM |
Claims | — | View | |
| 2026-01-09 | REM |
Applicant Arguments/Remarks Made in an Amendment | — | View | |
| 2026-01-09 | N417.PYMT |
Electronic Fee Payment | — | View | |
| 2026-01-09 | N417 |
Electronic Filing System Acknowledgment Receipt | — | View | |
| 2026-01-09 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2025-10-10 | CTRS |
Requirement for Restriction/Election | 10 | View | |
| 2025-10-10 | 892 |
List of references cited by examiner | 1 | View | |
| 2025-10-10 | FOR |
Foreign Reference | 151 | View | |
| 2025-05-02 | N417 |
Electronic Filing System Acknowledgment Receipt | — | View | |
| 2025-05-02 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | — | View | |
| 2025-05-02 | REF.OTHER |
Other reference-Patent/Application/Search Documents | — | View | |
| 2025-05-02 | TRAN.LET |
Transmittal Letter | — | View | |
| 2025-05-02 | REF.OTHER |
Other reference-Patent/Application/Search Documents | — | View | |
| 2024-05-15 | M903 |
Notice of Designated Office (DO) / Elected Office (EO) Acceptance Mailed | 2 | View | |
| 2024-05-15 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2024-05-15 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2023-11-08 | N417 |
Electronic Filing System Acknowledgment Receipt | — | View | |
| 2023-11-08 | N417 |
Electronic Filing System Acknowledgment Receipt | — | View | |
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| 2023-11-08 | IDS |
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| 2023-11-08 | N417 |
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| 2023-11-08 | TRAN.LET |
Transmittal Letter | — | View | |
| 2023-11-08 | FOR |
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| 2023-11-08 | PEFR |
Applicant Response to Pre-Exam Formalities Notice | — | View | |
| 2023-11-08 | OATH |
Oath or Declaration filed | — | View | |
| 2023-11-08 | PEFR |
Applicant Response to Pre-Exam Formalities Notice | — | View | |
| 2023-11-08 | CLM |
Claims | — | View | |
| 2023-11-08 | REM |
Applicant Arguments/Remarks Made in an Amendment | — | View | |
| 2023-11-08 | N417 |
Electronic Filing System Acknowledgment Receipt | — | View | |
| 2023-11-08 | N417.PYMT |
Electronic Fee Payment | — | View | |
| 2023-10-19 | NTC.PUB |
Notice of Publication | 1 | View | |
| 2023-07-10 | WCLM |
Claims Worksheet (PTO-2022) | 4 | View | |
| 2023-07-10 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2023-07-10 | 371.FEE.M923 |
371 (National Stage) Supplemental Fees Missing - Form M923 | 2 | View | |
| 2023-07-10 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2023-03-21 | CRFE |
Sequence Listing in Computer Readable Format, No errors found | — | View | |
| 2023-03-21 | CRFE |
Sequence Listing in Computer Readable Format, No errors found | 15 | View | |
| 2023-03-08 | PA.. |
Power of Attorney | — | View | |
| 2023-03-08 | TRNA |
Transmittal of New Application | — | View | |
| 2023-03-08 | TRAN.LET |
Transmittal Letter | — | View | |
| 2023-03-08 | FOR |
Foreign Reference | — | View | |
| 2023-03-08 | N417.PYMT |
Electronic Fee Payment | — | View | |
| 2023-03-08 | N417 |
Electronic Filing System Acknowledgment Receipt | — | View | |
| 2023-03-08 | ADS |
Application Data Sheet | — | View | |
| 2023-03-08 | FOR |
Foreign Reference | — | View | |
| 2023-03-08 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | — | View | |
| 2023-03-08 | PA.. |
Power of Attorney | — | View | |
| 2023-03-08 | R3.73 |
Assignee showing of ownership per 37 CFR 3.73 | — | View | |
| 2023-03-08 | P.N.101.CONV |
PCT/RO/101 - Request form for new International Application - Conventional | 5 | View | |
| 2023-03-08 | 371P |
Documents submitted with 371 (National Stage) Applications | 1 | View | |
| 2023-03-08 | FRPR |
Certified Copy of Foreign Priority Application | 291 | View | |
| 2023-03-08 | 371P |
Documents submitted with 371 (National Stage) Applications | 1 | View | |
| 2023-03-08 | ABST |
Abstract | 1 | View | |
| 2023-03-08 | SPEC |
Specification | 271 | View | |
| 2023-03-08 | CLM |
Claims | 46 | View | |
| 2023-03-08 | ABST |
Abstract | 1 | View | |
| 2023-03-08 | SPEC |
Specification | 271 | View | |
| 2023-03-08 | CLM |
Claims | 46 | View | |
| 2023-03-08 | ABST |
Abstract | 1 | View | |
| 2023-03-08 | SEQ.TXT |
Sequence Listing (Text File) | 1 | View |
Inventors
JAMES D. MCININCH
BURLINGTON, MA
AIMEE DEATON
SOMERVILLE, MA
LUCAS BONDURANT
BROOKLINE, MA
MARK K. SCHLEGEL
LEXINGTON, MA
ADAM CASTORENO
FRAMINGHAM, MA
Attorneys & Agents of Record
Classification
USPC
514/44A
C12N15/113
C12N2310/14
C12N2310/315
C12N2310/321
C12N2310/322
C12N2310/351
C12N2310/3515
Prosecution
- Examiner
- ARIETI, RUTH SOPHIA
- Art Unit
- 1635
- Customer No.
- 168188
- Docket No.
- A108868 1150US.PCT 370.9
- Confirmation No.
- 6647
Publication
- Pub. No.
- US20230332147A1
- Pub. Date
- 2023-10-19
SECURITY INTEREST
Recorded 2025-10-01
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded 2023-03-09
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Quick Facts
- App. No.
- 18/044,401
- Filed
- 2023-03-08
- Pub. No.
- US20230332147A1
- Examiner
- ARIETI, RUTH SOPHIA
- Art Unit
- 1635
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