Compression garment assembly for applying TTFields and methods of production and use thereof

1. A garment, comprising:

a support layer configured to be worn by a patient, the support layer sized and dimensioned to cover at least a portion of the patient and associated with a transducer array fastener;

a transducer array having a skin-facing surface and a complementary array fastener associated with a surface opposite the skin-facing surface, the complementary array fastener operable to be coupled with the transducer array fastener, the transducer array having a first edge and a second edge opposite the first edge; and

a protective layer disposed on the skin-facing surface of the transducer array, the protective layer having a release member extending from the protective layer adjacent to the first edge of the transducer array and extending beyond the second edge of the transducer array, wherein the protective layer and the release member are formed from a contiguous material wherein the contiguous material forms a “U” shape.

2. The garment of claim 1 , wherein the protective layer and the release member are formed of a non-conductive material.

3. The garment of claim 1 , wherein the transducer array further comprises a medical gel disposed on the skin-facing surface of the transducer array and between the transducer array and the protective layer.

4. The garment of claim 3 , wherein the transducer array does not include an attaching component separate from the medical gel, the attaching component configured to attach the transducer array to the patient.

5. The garment of claim 1 , wherein the release member extends beyond the support layer.

6. The garment of claim 1 , wherein the first edge of the transducer array and the second edge of the transducer array are at least partially opposing.

7. The garment of claim 1 , wherein the transducer array is a first transducer array, the garment further comprising a second transducer array, and an electric field generator, the electric field generator operable to supply a TTField signal to each of the first transducer array and the second transducer array and cause the first transducer array and the second transducer array to generate a TTField based on the TTField signal.

8. A garment, comprising:

a support layer configured to be worn by a patient, the support layer sized and dimensioned to cover at least a portion of the patient and associated with a transducer array fastener;

a transducer array having a first edge, a second edge, a skin-facing surface, and a complementary array fastener associated with a surface opposite the skin-facing surface, the transducer array fastener operable to be coupled with the complementary array fastener;

a first protective layer disposed on the skin-facing surface of the transducer array, the first protective layer covering a first portion of the transducer array, and having a first release member extending from the first protective layer and extending beyond the second edge of the transducer array, wherein the first protective layer and the first release member are formed from a contiguous material wherein the contiguous material forms a “U” shape; and

a second protective layer disposed on the skin-facing surface of the transducer array, the second protective layer covering a second portion of the transducer array, and having a second release member extending from the second protective layer and extending beyond the first edge of the transducer array.

9. The garment of claim 8 , wherein the second protective layer and the second release member are formed from a second contiguous material.

10. The garment of claim 8 , wherein the first protective layer and the second protective layer are formed of a non-conductive material.

11. The garment of claim 8 , wherein the transducer array further comprises a medical gel disposed on the skin-facing surface of the transducer array and between the transducer array and the first protective layer and the second protective layer.

12. The garment of claim 11 , wherein the transducer array does not include an attaching component separate from the medical gel, the attaching component configured to attach the transducer array to the patient.

13. The garment of claim 8 , wherein the first release member and the second release member extend beyond the support layer.

14. The garment of claim 8 , wherein the first edge of the transducer array is a top of the transducer array and the second edge of the transducer array is a bottom of the transducer array.

15. The garment of claim 8 , wherein the transducer array has a midline between the first edge of the transducer array and the second edge of the transducer array, and wherein at least one of the first protective layer and the second protective layer extends beyond the midline.

16. The garment of claim 8 , wherein the transducer array is a first transducer array, the garment further comprising a second transducer array, and an electric field generator, the electric field generator operable to supply a TTField signal to each of the first transducer array and the second transducer array and cause the first transducer array and the second transducer array to generate a TTField based on the TTField signal.

17. A method comprising:

applying a support layer of a garment to a patient so as to apply a first transducer array to a treatment area such that the first transducer array and a second transducer array are associated with the treatment area, the support layer configured to be worn by the patient, the support layer sized and dimensioned to cover at least a portion of the patient, the support layer having the first transducer array attached thereto, the first transducer array having a skin-facing surface and a protective layer disposed on the skin-facing surface of the first transducer array, the protective layer having a release member between the protective layer and the patient and extending from the protective layer to at least the support layer, wherein the protective layer and the release member are formed from a contiguous material wherein the contiguous material forms a “U” shape;

removing the protective layer by pulling the release member extending beyond the support layer until the protective layer is detached from the skin-facing surface of the first transducer array; and

supplying an alternating current electric signal having a frequency between 50 kHz and 1 MHz to the first transducer array and the second transducer array.

18. The method of claim 17 , wherein the support layer further includes an adjustment assembly attached thereto, the adjustment assembly adjustable between a first position and a second position; the method further comprising, before removing the protective layer, adjusting the adjustment assembly such that the first transducer array and the second transducer array cover at least a portion of the treatment area.

19. The method of claim 17 , wherein the first transducer array further includes a medical gel disposed between the first transducer array and the protective layer, and wherein removing the protective layer further includes removing the protective layer by pulling the release member extending beyond an edge of the first transducer array until the medical gel is exposed and applicable to skin of the patient.