IP Library Granted Patent US 11,869,669
Granted Patent B2
US 11,869,669 · App. 18/068,604 · Granted Jan 9, 2024

Method and system for image processing to model vasculasture

Inventors: Ryan Spilker (Arlington, MA); David Eberle (San Francisco, CA); Leo Grady (Darien, CT)
Assignee: HeartFlow, Inc.
G16H50/50A61B34/10G06F30/20G06T7/0012G06T7/11G06T7/20G06V10/40G06V30/194G06V40/20G16H20/40G16H30/20G16H50/20A61B2034/104A61B2034/105A61B2034/107G06T2207/20112G06T2207/30096G06T2207/30101G06T2207/30104G06V10/467
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,869,669
App. No.
18/068,604
Granted
Jan 9, 2024
Kind
B2
Abstract

Systems and methods are disclosed for evaluating cardiovascular treatment options for a patient. One method includes creating a three-dimensional model representing a portion of the patient's heart based on patient-specific data regarding a geometry of the patient's heart or vasculature; and for a plurality of treatment options for the patient's heart or vasculature, modifying at least one of the three-dimensional model and a reduced order model based on the three-dimensional model. The method also includes determining, for each of the plurality of treatment options, a value of a blood flow characteristic, by solving at least one of the modified three-dimensional model and the modified reduced order model; and identifying one of the plurality of treatment options that solves a function of at least one of: the determined blood flow characteristics of the patient's heart or vasculature, and one or more costs of each of the plurality of treatment options.

Claims (40)

1. A vascular modeling method, comprising:

receiving patient-specific data imaging data of a vasculature of a patient;

determining that a vessel of the vasculature of the patient includes a plaque;

automatically segmenting the vessel of the patient that includes the plaque;

generating a set of possible treatment options for at least a section of the patient's vasculature having energy losses exceeding a predetermined threshold level, wherein the set of possible treatment options includes all feasible treatment options for the at least the section;

evaluating the set of possible treatment options; and

generating a patient-specific treatment recommendation based on the evaluating the set of possible treatment options.

2. The method of claim 1 , wherein the plaque is automatically segmented based on a contrast of the plaque as compared to a wall of the vessel.

3. The method of claim 1 , wherein the determining that the vessel of the vasculature of the patient includes the plaque includes comparing an intensity value of the patient-specific imaging data to a threshold value.

4. The method of claim 1 , wherein the evaluating the set of possible treatment options includes applying an objective function.

5. The method of claim 4 , wherein the objective function maximizes flow or minimizes pressure changes.

6. The method of claim 5 , wherein the objective function penalizes undesirable characteristics.

7. The method of claim 4 , wherein the objective function identifies a local optimum.

8. The method of claim 1 , wherein the patient-specific treatment recommendation includes a stent or a bypass graft, the method further comprising displaying a type, location, and/or orientation of the stent or the bypass graft.

9. A system for vascular modeling, the system comprising:

at least one memory having processor-readable instructions stored therein; and

at least one processor configured to access the memory and execute the processor-readable instructions, which when executed by the processor configures the processor to perform a plurality of operations, the operations comprising:

receiving patient-specific data imaging data of a vasculature of a patient;

determining that a vessel of the vasculature of the patient includes a plaque;

automatically segmenting the vessel of the patient that includes the plaque;

generating a set of possible treatment options for at least a section of the patient's vasculature having energy losses exceeding a predetermined threshold level, wherein the set of possible treatment options includes all feasible treatment options for the at least the section;

evaluating the set of possible treatment options; and

generating a patient-specific treatment recommendation based on the evaluating the set of possible treatment options.

10. The system of claim 9 , wherein the plaque is automatically segmented based on a contrast of the plaque as compared to a wall of the vessel.

11. The system of claim 9 , wherein the determining that the vessel of the vasculature of the patient includes the plaque includes comparing an intensity value of the patient-specific imaging data to a threshold value.

12. The system of claim 9 , wherein the evaluating the set of possible treatment options includes applying an objective function.

13. The system of claim 12 , wherein the objective function maximizes flow or minimizes pressure changes.

14. The system of claim 13 , wherein the objective function penalizes undesirable characteristics.

15. A non-transitory computer readable medium storing computer program instructions for planning treatment for vascular modeling, the computer program instructions when executed by a processor causes the processor to perform operations comprising:

receiving patient-specific data imaging data of a vasculature of a patient;

determining that a vessel of the vasculature of the patient includes a plaque;

automatically segmenting the vessel of the patient that includes the plaque;

generating a set of possible treatment options for at least a section of the patient's vasculature having energy losses exceeding a predetermined threshold level, wherein the set of possible treatment options includes all feasible treatment options for the at least the section;

evaluating the set of possible treatment options; and

generating a patient-specific treatment recommendation based on the evaluating the set of possible treatment options.

16. The non-transitory computer readable medium of claim 15 , wherein the plaque is automatically segmented based on a contrast of the plaque as compared to a wall of the vessel.

17. The non-transitory computer readable medium of claim 15 , wherein the determining that the vessel of the vasculature of the patient includes the plaque includes comparing an intensity value of the patient-specific imaging data to a threshold value.

18. The non-transitory computer readable medium of claim 15 , wherein the evaluating the set of possible treatment options includes applying an objective function.

19. The non-transitory computer readable medium of claim 18 , wherein the objective function maximizes flow or minimizes pressure changes.

20. The non-transitory computer readable medium of claim 19 , wherein the objective function penalizes undesirable characteristics.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Sep 11, 2025
From: HAYFIN SERVICES LLP
To: HEARTFLOW, INC.
Reel/Frame 072876/0775 →
SECURITY INTEREST Recorded Jun 18, 2024
From: HEARTFLOW, INC.
To: HAYFIN SERVICES LLP
Reel/Frame 067775/0966 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 20, 2022
From: SPILKER, RYAN; EBERLE, DAVID; GRADY, LEO
To: HEARTFLOW, INC.
Reel/Frame 062160/0067 →