IP Library Patent Application 18109510
Patent Application
App. No. 18/109,510

SYSTEMS AND METHODS FOR DELIVERY OF THERAPEUTIC GAS

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Quick Facts
Patent No.
US None
App. No.
18/109,510
Abstract

A therapeutic gas delivery system with at least one gas supply subsystem is disclosed. The at least one gas supply subsystem may include a gas source coupling configured to receive a therapeutic gas source and form a fluid flow connection with the therapeutic gas source, a therapeutic gas delivery system controller, and one or more display(s) configured to be in communication over a communication path with the therapeutic gas delivery system controller. The display may be configured to display a graphical, illustrative, or numerical indicator of one or more flow or system parameters.

Claims (46)

1 . A therapeutic gas delivery system comprising:

at least one gas supply subsystem comprising:

a gas source coupling configured to receive a therapeutic gas source and form a fluid flow connection with the therapeutic gas source;

a therapeutic gas delivery system controller; and

one or more display(s) configured to be in communication over a communication path with the therapeutic gas delivery system controller,

wherein the one or more display(s) are configured to display a graphical, illustrative, or numerical indicator of at least one of a flow parameter and/or a system parameter.

2 . The therapeutic gas delivery system of claim 1 , wherein the one or more display(s) are further configured to display a visual alarm.

3 . The therapeutic gas delivery system of claim 2 , wherein the therapeutic gas delivery system controller is configured to produce an audible alarm.

4 . The therapeutic gas delivery system of claim 1 , wherein the one or more display(s) are configured to display a bar graph, a chart, or a numerical display of a value of the at least one of the flow parameter and/or the system parameter.

5 . The therapeutic gas delivery system of claim 1 , wherein the one or more display(s) are configured to present a graphic of the therapeutic gas delivery system comprising indicators for flow of the therapeutic gas through the system.

6 . The therapeutic gas delivery system of claim 5 , wherein the graphic of the therapeutic gas delivery system further comprises indicators for a status of the therapeutic gas source, a sample line, an injector module, expiratory tubing, an electronically controlled gas blending device, or combinations thereof.

7 . The therapeutic gas delivery system of claim 1 , the therapeutic gas is nitric oxide.

8 . The therapeutic gas delivery system of claim 7 , wherein the display is configured to present a concentration and/or flow rate of nitric oxide and breathing gas through the system.

9 . The therapeutic gas delivery system of claim 1 , further comprising an electrical power supply connection, an internal battery, and a power button, wherein the power button includes a power indicator that visually indicates an electrical power supply status of the electrical power supply connection and a battery charge status of the internal battery.

10 . The therapeutic gas delivery system of claim 9 , wherein one or more system parameters includes an electrical power supply status and a battery charge status.

11 . The therapeutic gas delivery system of claim 1 , further comprising an alarm silence button, wherein the alarm silence button includes an alarm indicator that visually indicates a status of one or more alarms of the therapeutic gas delivery system.

12 . The therapeutic gas delivery system of claim 1 , further comprising a global status indicator, wherein the global status indicator visually indicates one or more global statuses of the therapeutic gas delivery system.

13 . The therapeutic gas delivery system of claim 12 , wherein one or more of the global statuses include a delivery status and an alarm status.

14 . The therapeutic gas delivery system of claim 1 , further comprising an injector module outlet and a corresponding port indicator, wherein the port indicator visually indicates a delivery status of the injector module outlet.

15 . The therapeutic gas delivery system of claim 1 , further comprising a secondary delivery subsystem outlet and a corresponding port indicator, wherein the port indicator visually indicates a delivery status of the secondary delivery subsystem outlet.

16 . The therapeutic gas delivery system of claim 1 , wherein the therapeutic gas source includes a first compressed gas cylinder, wherein the one or more flow or system parameters includes a first cylinder status, wherein the first cylinder status visually indicates whether the first compressed gas cylinder is delivering therapeutic gas or is idle, wherein the first cylinder status includes a percentage of available therapeutic gas in the first compressed gas cylinder.

17 . The therapeutic gas delivery system of claim 16 , wherein the first cylinder status visually indicates if the first compressed gas cylinder is in a low priority alarm or a high priority alarm.

18 . The therapeutic gas delivery system of claim 16 , wherein the therapeutic gas source includes a second compressed gas cylinder, wherein the one or more flow or system parameters includes a second cylinder status, wherein the second cylinder status visually indicates whether the second compressed gas cylinder is delivering therapeutic gas or is idle, wherein the second cylinder status includes a percentage of available therapeutic gas in the second compressed gas cylinder.

19 . The therapeutic gas delivery system of claim 18 , wherein the second cylinder status visually indicates if the second compressed gas cylinder is in a low priority alarm or a high priority alarm.

20 . The therapeutic gas delivery system of claim 1 , wherein the one or more flow or system parameters includes at least one of a left cylinder status, right cylinder status, a patient line status, a sample gas sample line status, a delivery conduit status, an injector module status, a patient gas sample line status, and a breathing circuit expiratory limb status.

21 . The therapeutic gas delivery system of claim 1 , wherein the one or more flow or system parameters includes at least one of a secondary delivery subsystem status and dose.

22 . The therapeutic gas delivery system of claim 1 , wherein at least one gas supply system includes a secondary delivery subsystem, wherein the one or more displays is configured to display the delivery of therapeutic gas through the secondary delivery subsystem.

23 . The therapeutic gas delivery system of claim 22 , further comprising a breathing circuit, wherein the one or more displays is configured to display the delivery of therapeutic gas to the breathing circuit.

24 . The therapeutic gas delivery system of claim 23 , wherein the breathing circuit is a t-piece resuscitator circuit, an infant resuscitator circuit, or an infant t-piece resuscitator circuit.

25 . The therapeutic gas delivery system of claim 1 , wherein at least one gas supply system includes a therapeutic gas delivery system, wherein the one or more displays is configured to display the delivery of therapeutic gas through the therapeutic gas delivery system.

26 . The therapeutic gas delivery system of claim 25 , further comprising a breathing circuit, wherein the one or more displays is configured to display the delivery of therapeutic gas to the breathing circuit.

27 . The therapeutic gas delivery system of claim 26 , wherein the breathing circuit is a conventional ventilator circuit, an anesthesia circuit, a spontaneous circuit, a nasal cannula circuit, a high frequency jet ventilation circuit, a high frequency oscillatory ventilator unfiltered circuit, a dual-limb transport ventilator circuit, or a single-limb transport ventilator circuit.

28 . The therapeutic gas delivery system of claim 26 , wherein the breathing circuit is a high frequency oscillatory ventilator filtered circuit, an infant flow circuit, a precision flow circuit, a continuous positive airway pressure system circuit, a high flow breathing circuit, a high flow infant circuit nasal cannula circuit, or a high flow nasal cannula oxygen therapy circuit.

29 . A therapeutic gas delivery system comprising:

a first gas supply subsystem comprising a first compressed gas cylinder configured to supply therapeutic gas;

a second gas supply subsystem comprising a second compressed gas cylinder configured to supply therapeutic gas; and

a therapeutic gas delivery system controller,

wherein the therapeutic gas delivery system receives therapeutic gas from the first compressed gas cylinder until the first compressed gas cylinder is depleted, wherein when the first compressed gas cylinder is depleted the therapeutic gas delivery system controller performs an automatic switchover such that the therapeutic gas delivery system receives therapeutic gas from the second compressed gas cylinder.

30 . The therapeutic gas delivery system of claim 29 , wherein the automatic switchover provides continuous uninterrupted delivery of therapeutic gas to a patient.

31 . The therapeutic gas delivery system of claim 29 , wherein the therapeutic gas delivery system receiving therapeutic gas from the second compressed gas cylinder provides time to disconnect the first compressed gas cylinder and connect a replacement compressed gas cylinder to the first gas supply subsystem.

32 . The therapeutic gas delivery system of claim 31 , wherein the replacement compressed gas cylinder includes a cylinder concentration such that the cylinder concentration can be verified before the replacement compressed gas cylinder is connected.

33 . The therapeutic gas delivery system of claim 31 , wherein the replacement compressed gas cylinder includes an expiration date such that the expiration date can be verified before the replacement compressed gas cylinder is connected.

34 . The therapeutic gas delivery system of claim 29 , further comprising at least one display in communication with the therapeutic gas delivery system controller, wherein the at least one display is configured to display a visual alarm when the first compressed gas cylinder is depleted.

35 . The therapeutic gas delivery system of claim 34 , wherein the at least one display is configured to display a visual alarm if a replacement compressed gas cylinder is not full with therapeutic gas.

36 . The therapeutic gas delivery system of claim 29 , wherein the therapeutic gas delivery system controller produces an audible alarm when the first compressed gas cylinder is depleted.

37 . The therapeutic gas delivery system of claim 36 , wherein the therapeutic gas delivery system controller produces an audible alarm if a replacement compressed gas cylinder is not full of therapeutic gas.

Assignments (14)
CORRECTIVE ASSIGNMENT TO CORRECT THE INCLUSION OF US PATENT 10828415 AND REMOVE IT FROM THE LISTING PREVIOUSLY RECORDED ON REEL 73375 FRAME 395. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY INTEREST. Recorded Mar 6, 2026
From: MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED
To: GOLDMAN SACHS BANK USA, AS ADMINISTRATIVE AGENT
Reel/Frame 075021/0263 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCLUSION OF US PATENT 10828415 AND REMOVE IT FROM THE LISTING PREVIOUSLY RECORDED ON REEL 72331 FRAME 1. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY INTEREST. Recorded Mar 6, 2026
From: MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED
To: COMPUTERSHARE TRUST COMPANY, NATIONAL ASSOCIATION
Reel/Frame 075021/0204 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 31, 2025
From: THERAKOS, INC.
To: MALLINCKRODT CRITICAL CARE FINANCE INC.
Reel/Frame 073348/0099 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 31, 2025
From: MALLINCKRODT CRITICAL CARE FINANCE INC.
To: MALLINCKRODT PHARMA IP TRADING DAC
Reel/Frame 073348/0162 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 31, 2025
From: MALLINCKRODT PHARMA IP TRADING DAC
To: MALLINCKRODT IP
Reel/Frame 073348/0266 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 31, 2025
From: MALLINCKRODT IP
To: MALLINCKRODT HOSPITAL PRODUCTS IP LIMITED
Reel/Frame 073348/0361 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 31, 2025
From: MALLINCKRODT HOSPITAL PRODUCTS IP UNLIMITED COMPANY
To: MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED
Reel/Frame 073348/0475 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 31, 2025
From: ACKER, JARON M.; MILSAP, JEFF; ROEHL, ROBIN; SCHMIDT, JEFFREY; TOLMIE, CRAIG R.
To: INO THERAPEUTICS LLC
Reel/Frame 073347/0923 →
CHANGE OF NAME Recorded Dec 31, 2025
From: MALLINCKRODT HOSPITAL PRODUCTS IP LIMITED
To: MALLINCKRODT HOSPITAL PRODUCTS IP UNLIMITED COMPANY
Reel/Frame 074162/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 31, 2025
From: INO THERAPEUTICS LLC
To: THERAKOS, INC.
Reel/Frame 073348/0001 →
SECURITY INTEREST Recorded Oct 28, 2025
From: MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED
To: GOLDMAN SACHS BANK USA, AS ADMINISTRATIVE AGENT
Reel/Frame 073375/0395 →
RELEASE OF SECURITY INTEREST Recorded Aug 14, 2025
From: ACQUIOM AGENCY SERVICES LLC
To: MALLINCKRODT ENTERPRISES LLC; MALLINCKRODT LLC; MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY; MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED; OCERA THERAPEUTICS LLC; SPECGX LLC; STRATATECH CORPORATION; SUCAMPO PHARMA AMERICAS LLC; VTESSE LLC
Reel/Frame 072324/0740 →
SECURITY INTEREST Recorded Aug 1, 2025
From: MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED
To: COMPUTERSHARE TRUST COMPANY, NATIONAL ASSOCIATION
Reel/Frame 072331/0001 →
SECURITY INTEREST Recorded Nov 15, 2023
From: MALLINCKRODT ENTERPRISES LLC; MALLINCKRODT LLC; MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY; MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED; OCERA THERAPEUTICS LLC; SPECGX LLC; STRATATECH CORPORATION; SUCAMPO PHARMA AMERICAS LLC; VTESSE LLC
To: ACQUIOM AGENCY SERVICES LLC
Reel/Frame 065595/0376 →