IP Library Granted Patent US 11,857,782
Granted Patent B2
US 11,857,782 · App. 18/109,539 · Granted Jan 2, 2024

Delivering tumor treating fields (TTFields) using implantable transducer arrays

Inventors: Yoram Wasserman (Haifa, IL); Zeev Bomzon (Kiryat Tivon, IL); Hadas Sara Hershkovich (Kiryat Motzkin, IL); Ariel Naveh (Haifa, IL); Moshe Giladi (Haifa, IL); Eilon Kirson (Ramat Hasharon, IL); Golan Bar-Tal (Haifa, IL); Tali Voloshin-Sela (Haifa, IL)
Assignee: Novocure GmbH
A61N1/36002A61N1/05A61N1/3787
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Quick Facts
Patent No.
US 11,857,782
App. No.
18/109,539
Granted
Jan 2, 2024
Kind
B2
Abstract

Tumor treating fields (TTFields) can be delivered by implanting a plurality of sets of implantable electrode elements within a person's body. Temperature sensors positioned to measure the temperature at the electrode elements are also implanted, along with a circuit that collects temperature measurements from the temperature sensors. In some embodiments, an AC voltage generator configured to apply an AC voltage across the plurality of sets of electrode elements is also implanted within the person's body.

Claims (11)

1. An apparatus for delivering tumor treating fields, the apparatus comprising:

a plurality of sets of electrode elements, wherein each of the sets of electrode elements is configured for implantation within a person's body;

a plurality of temperature sensors configured for implantation within the person's body and positioned to measure a temperature at each of the sets of electrode elements;

a plurality of multiplexors configured for implantation within the person's body, wherein each of the multiplexors is positioned to reduce a number of conductors that are required to obtain temperature measurements from a respective subset of the temperature sensors and to forward the obtained temperature measurements to an output; and

a circuit configured for implantation within the person's body configured for collecting the temperature measurements that have been forwarded by the multiplexors.

2. The apparatus of claim 1 , wherein each of the sets of electrode elements comprises a plurality of capacitively coupled electrode elements.

3. The apparatus of claim 1 , wherein each of the temperature sensors comprises a thermistor.

4. The apparatus of claim 1 , wherein the plurality of sets of electrode elements, the plurality of temperature sensors, the plurality of multiplexors, and the circuit are all implanted in the person's body.

5. The apparatus of claim 1 , wherein each of one or more electrode elements in each of the sets of electrode elements is associated with a respective one of the temperature sensors.

6. The apparatus of claim 1 , wherein each of the electrode elements is associated with a respective one of the temperature sensors.

7. The apparatus of claim 6 , wherein the circuit is configured to control a current that is applied to each individual electrode element based on signals from the plurality of temperature sensors so that the electrode elements do not overheat.

Assignments (3)
CORRECTIVE ASSIGNMENT TO CORRECT THE INVENTOR EXECUTION DATE PREVIOUSLY RECORDED AT REEL: 62872 FRAME: 451. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Aug 13, 2025
From: KIRSON, EILON
To: NOVOCURE GMBH
Reel/Frame 072421/0256 →
PATENT SECURITY AGREEMENT Recorded May 4, 2024
From: NOVOCURE GMBH (SWITZERLAND)
To: BIOPHARMA CREDIT PLC
Reel/Frame 067315/0399 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 3, 2023
From: WASSERMAN, YORAM; BOMZON, ZEEV; HERSHKOVICH, HADAS SARA; NAVEH, ARIEL; GILADI, MOSHE; KIRSON, EILON; BAR-TAL, GOLAN; VOLOSHIN-SELA, TALI
To: NOVOCURE GMBH
Reel/Frame 062872/0451 →