IP Library Granted Patent US 11,865,369
Granted Patent B2
US 11,865,369 · App. 18/114,826 · Granted Jan 9, 2024

Neural network calibration for radiotherapy

Inventors: Mikko Hakala (Rajamaki, FI); Esa Kuusela (Espoo, FI); Elena Czeizler (Helsinki, FI); Shahab Basiri (Siuntio, FI)
Assignee: Siemens Healthineers International AG
A61N5/1064G06N3/045G06N3/08G06N20/00
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Quick Facts
Patent No.
US 11,865,369
App. No.
18/114,826
Granted
Jan 9, 2024
Kind
B2
Abstract

Disclosed herein are systems and methods for identifying radiation therapy treatment data for patients. A processor accesses a neural network trained based on a first set of data generated from characteristic values of a first set of patients that received treatment at one or more first radiotherapy machines. The processor executes the neural network using a second set of data comprising characteristic values of a second set of patients receiving treatment at one or more second radiotherapy machines. The processor executes a calibration model using an output of the neural network based on the second set of data to output a calibration value. The processor executes the neural network using a set of characteristics of a first patient to output a first confidence score associated with a first treatment attribute. The processor then adjusts the first confidence score according to the calibration value to predict the first treatment attribute.

Claims (41)

1. A method comprising:

retrieving, by one or more processors, a set of treatment attribute predictions for a radiotherapy treatment of a patient;

executing, by the one or more processors, a calibration model using the set of treatment attribute predictions and a set of labels indicating expected treatment attribute predictions to output a calibration value;

executing, by the one or more processors, an artificial intelligence model using a set of characteristics of the patient to output a confidence score associated with at least one treatment attribute prediction of the set of treatment attribute predictions; and

adjusting, by the one or more processors, at least one confidence score according to the calibration value.

2. The method of claim 1 , wherein the set of treatment attribute predictions is received from the artificial intelligence model.

3. The method of claim 1 , further comprising:

executing, by the one or more processors, the artificial intelligence model using a set of characteristics of a second patient to output a second confidence score associated with a second treatment attribute prediction and adjusting the second confidence score according to the calibration value to predict a revised second treatment attribute prediction.

4. The method of claim 1 , further comprising:

adjusting, by the one or more processors, a configuration of a radiotherapy machine according to at least one treatment attribute prediction.

5. The method of claim 1 , further comprising:

presenting, by the one or more processors for display, the adjusted confidence score and the first treatment attribute.

6. The method of claim 5 , further comprising:

responsive to receiving the user input, adjusting, by the one or more processors, a configuration of the radiotherapy machine.

7. The method of claim 5 , further comprising:

responsive to receiving the user input, adjusting, by the one or more processors, a configuration of the radiotherapy machine.

8. The method of claim 1 , further comprising:

adjusting, by the one or more processors, the artificial intelligence model in accordance with the calibration value.

9. The method of claim 1 , wherein the treatment attribute is an angle associated with a couch or a gantry of a radiotherapy machine.

10. The method of claim 1 , wherein the calibration model is one of a machine learning model or a mathematical optimization algorithm.

11. A system comprising:

a non-transitory computer readable medium comprising a set of instructions, that when executed, cause at least one processor to:

retrieve a set of treatment attribute predictions for a radiotherapy treatment of a patient;

execute a calibration model using the set of treatment attribute predictions and a set of labels indicating expected treatment attribute predictions to output a calibration value;

execute an artificial intelligence model using a set of characteristics of the patient to output a confidence score associated with at least one treatment attribute prediction of the set of treatment attribute predictions; and

adjust at least one confidence score according to the calibration value.

12. The system of claim 11 , wherein the set of treatment attribute predictions is received from the artificial intelligence model.

13. The system of claim 11 , wherein the instructions further cause the processor to:

execute the artificial intelligence model using a set of characteristics of a second patient to output a second confidence score associated with a second treatment attribute prediction and adjusting the second confidence score according to the calibration value to predict a revised second treatment attribute prediction.

14. The system of claim 11 , wherein the instructions further cause the processor to:

adjust a configuration of a radiotherapy machine according to at least one treatment attribute prediction.

15. The system of claim 11 , wherein the instructions further cause the processor to:

present, for display, the adjusted confidence score and the first treatment attribute.

16. The system of claim 15 , wherein the instructions further cause the processor to:

responsive to receiving the user input, adjust a configuration of the radiotherapy machine.

17. The system of claim 15 , wherein the instructions further cause the processor to:

responsive to receiving the user input, adjust a configuration of the radiotherapy machine.

18. The system of claim 11 , wherein the instructions further cause the processor to:

adjust the artificial intelligence model in accordance with the calibration value.

19. The system of claim 11 , wherein the treatment attribute is an angle associated with a couch or a gantry of a radiotherapy machine.

20. The system of claim 11 , wherein the calibration model is one of a machine learning model or a mathematical optimization algorithm.

Assignments (4)
MERGER AND CHANGE OF NAME Recorded Apr 20, 2023
From: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG; SIEMENS HEALTHINEERS INTERNATIONAL AG
To: SIEMENS HEALTHINEERS INTERNATIONAL AG
Reel/Frame 063396/0598 →
MERGER AND CHANGE OF NAME Recorded Mar 15, 2023
From: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG; SIEMENS HEALTHINEERS INTERNATIONAL AG
To: SIEMENS HEALTHINEERS INTERNATIONAL AG
Reel/Frame 063409/0731 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 27, 2023
From: HAKALA, MIKKO; KUUSELA, ESA; CZEIZLER, ELENA; BASIRI, SHAHAB
To: VARIAN MEDICAL SYSTEMS, INC.
Reel/Frame 062816/0759 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 27, 2023
From: VARIAN MEDICAL SYSTEMS, INC.
To: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG
Reel/Frame 062816/0810 →
Continuity (2)
Continuation 17124223 · Dec 16, 2020
Related Publication 20230211184A1 · Jul 6, 2023