TISSUE MATRICES INCORPORATING MULTIPLE TISSUE TYPES
The present disclosure provides tissue products produced from extracellular tissue matrices. The tissue products can include acellular extracellular matrices including combinations of different tissue types. The combination can harness various properties of the different tissues to provide improved composite structures with desired mechanical and/or biologic properties.
1 . A tissue product, comprising:
a first component comprising an intact acellular tissue matrix; and
a second component comprising a porous acellular tissue matrix sponge covering at least a portion of the intact acellular tissue matrix, wherein the porous acellular tissue matrix sponge comprises a tissue matrix that has been mechanically homogenized, resuspended, and stabilized, and wherein the intact acellular tissue matrix comprises a group of openings in which the porous acellular tissue matrix sponge is positioned such that the intact acellular tissue matrix provides mechanical support to the porous acellular tissue matrix sponge.