Adaptive pressure-cyclical aspiration device and methods
An aspiration system operable for relieving occlusions caused by clots and other lodged bodies in a vessel uses a cyclic algorithm which is adaptable to receipt of any known or developed aspiration catheter to treat acute ischemic occlusions by applied alternating catheter pressure within a defined range. The application of the algorithm is customizable by the specific physical characteristics of the catheter selected, making the system universally applicable to a significant range of catheters. A user interface may be provided conveniently within reach of the user enabling interactive input of intervening selections based on recommendations by a processor running the algorithm.
1 . A method of aspirating a thrombus from a body lumen via a catheter coupled to a pump assembly, the pump assembly including a pump, the method comprising:
receiving at a controller an input associated with a catheter parameter associated with the catheter coupled to the pump assembly, the controller implemented in at least one of a memory or a processor coupled to the pump assembly;
selecting, via the controller, an aspiration algorithm associated with the catheter parameter, the aspiration algorithm including an upper pressure limit, a lower pressure limit, a clockwise speed, and a counter clockwise speed;
sending a first command to actuate the pump based on the aspiration algorithm to operate the pump in a first mode;
receiving at the controller a pressure signal associated with a catheter pressure from a sensor of the pump assembly; and
sending, on a condition that the catheter pressure is below a pressure threshold, a second command to actuate the pump based on the aspiration algorithm to operate the pump in a second mode during which the pump is cycled between the clockwise speed and the counter clockwise speed such that the catheter pressure cycles between the upper pressure limit and the lower pressure limit.
2 . The method of claim 1 , further comprising:
receiving a user input associated with the catheter from a drop-down menu.
3 . The method of claim 1 , wherein the catheter parameter includes at least one of an inner diameter of the catheter, a compliance of the catheter, or a length of the catheter.
4 . The method of claim 1 , wherein the body lumen is a blood vessel, and the upper pressure limit is less than a blood pressure within the blood vessel.
5 . The method of claim 1 , wherein the first mode includes operating the pump at the clockwise speed.
6 . The method of claim 5 , further comprising:
after the sending the second command to actuate the pump to operate in a second mode, receiving at the controller a second pressure signal associated with a second catheter pressure from the sensor of the pump assembly; and
sending a notification to withdraw the catheter from the body lumen on a condition that the second catheter pressure is below a preset pressure limitation indicating a plugged state.
7 . The method of claim 1 , further comprising:
sending a notification to withdraw the catheter from the body lumen on a condition that a time period of operating the pump in the second mode has exceeded a time threshold thereby indicating a plugged state.
8 . The method of claim 1 , further comprising:
after the sending the second command to actuate the pump to operate the pump in the second mode, receiving a second pressure signal associated with a second catheter pressure from the sensor of the pump assembly; and
sending a third command to actuate the pump to operate the pump in a third mode based on the selected aspiration algorithm, the third mode includes operating the pump at the clockwise speed.
9 . An apparatus, comprising:
a thrombectomy pump assembly disposed within a housing, the thrombectomy pump assembly including a pump, the thrombectomy pump assembly configured to aspirate a thrombus from a body lumen via a catheter coupled to the pump;
a display coupled to the housing; and
a controller coupled within the housing, the controller including at least one of a memory or a processor, the controller configured to:
(1) receive a first input, the first input associated with a catheter parameter associated with a catheter to be coupled to the pump assembly, (2) select an aspiration algorithm associated with the catheter parameter, the aspiration algorithm including an upper pressure limit, a lower pressure limit, a clockwise speed, and a counter clockwise speed, (3) send a command based on the aspiration algorithm to the thrombectomy pump assembly to operate the thrombectomy pump assembly in a first mode, (4) receive a pressure signal associated with a catheter pressure from a sensor of the thrombectomy pump assembly, and (5) send a second command based on the aspiration algorithm to the thrombectomy pump assembly to operate the thrombectomy pump assembly in a second mode during which the pump is cycled between the clockwise speed and the counter clockwise speed such that the catheter pressure cycles between the upper pressure limit and the lower pressure limit.
10 . The apparatus of claim 9 , wherein the catheter parameter includes at least one of an inner diameter of the catheter, a compliance of the catheter, or a length of the catheter.
11 . The apparatus of claim 9 , wherein the body lumen is a blood vessel, and the upper pressure limit is less than a blood pressure within the blood vessel.
12 . The apparatus of claim 9 , wherein the first mode includes operating the pump at the clockwise speed.
13 . The apparatus of claim 12 , wherein the controller is further configured to:
receive, after the sending the second command to the pump assembly to operate the pump in the second mode, a second pressure signal associated with a second catheter pressure from the sensor of the pump assembly; and
send a notification to withdraw the catheter from the body lumen on a condition that the pressure is below a preset pressure limitation indicating a plugged state.
14 . The apparatus of claim 9 , wherein the controller is further configured to:
send a notification to withdraw the catheter from the body lumen on a condition that a time period of operating the pump in the second mode has exceeded a time threshold thereby indicating a plugged state.
15 . The apparatus of claim 9 , wherein the controller is further configured to:
receive, after the sending the second command to the pump assembly to operate the pump assembly in the second mode, a second pressure signal associated with a second catheter pressure from the sensor of the pump assembly; and
send a third command to the pump assembly to operate the pump assembly in a third mode based on the selected aspiration algorithm, the third mode includes operating the pump at the clockwise speed.
16 . A method of removing a thrombus from a body lumen via a catheter coupled to a pump assembly, the pump assembly including a pump, the method comprising:
selecting, via a controller, an aspiration algorithm including an upper pressure limit, a lower pressure limit, a clockwise speed, and a counter clockwise speed;
sending via the controller, a first command to the pump assembly to operate the pump assembly in a first mode based on the aspiration algorithm, the first mode including operating the pump at the clockwise speed;
receiving a first pressure signal associated with a catheter pressure from a sensor of the pump assembly;
sending via the controller in response to the first pressure signal, a second command to the pump assembly to operate the pump assembly in a second mode based on the aspiration algorithm during which the pump is cycled between the clockwise speed and the counter clockwise speed such that the catheter pressure cycles between the upper pressure limit and the lower pressure limit;
receiving at the controller a second pressure signal associated with a second catheter pressure from the sensor of the pump assembly; and
sending via the controller in response to the second pressure signal a third command to the pump assembly to operate the pump assembly in a third mode based on the aspiration algorithm, the third mode including operating the pump at the clockwise speed.
17 . The method of claim 16 , further comprising:
after the receiving the second pressure signal associated with the second catheter pressure from the sensor of the pump assembly, sending a notification to withdraw the catheter from the body lumen if the second catheter pressure is below a preset pressure limitation indicating a plugged state.