Granted Patent B2

US 12,557,994 · App. 18/136,542 · Granted Feb 24, 2026

Inventor: Alexander F. Castellanos (Templeton, CA)

Assignee: Alexander Castellanos

A61B5/0205A61B5/02007A61B8/0891A61B8/488A61B5/01A61B5/021A61B5/08A61B5/14542A61B8/4427

Abstract

Claims (55)

1 . A data processing method, comprising:

receiving, from at least one portable physiological measuring device configured for temporary attachment to a human body, data representing one or more physiological metrics of the body;

receiving, from one or more sensors configured for temporary attachment to peripheral artery locations of the body, vascular performance data for the body;

determining, by a portable signal measuring device, elasticity of one or more blood vessels based on the vascular performance data received from the one or more sensors;

inputting the data representing the physiological metrics and the elasticity of the one or more blood vessels to at least one algorithm;

performing, by the at least one algorithm, an analysis based on the physiological metrics and the elasticity of the one or more blood vessels;

wherein performing the analysis comprises:

determining one or more changes in the one or more physiological metrics;

wherein the one or more changes include one or more positive changes or one or more negative changes;

determining whether the one or more changes indicate an immediate physiological response or a delayed physiological response;

determining a number of vascular waveforms represented in the vascular performance data; and

based at least in part on the vascular waveforms, determining an interpretation of severity of the one or more changes;

generating and providing output records comprising one or more recommendations of responsive treatment, reports, animations, or figures based at least in part on the analysis;

wherein the method is performed by one or more computing devices.

2 . The method of claim 1 wherein the data representing one or more physiological metrics includes data indicative of rate of change in heartbeat.

3 . The method of claim 1 wherein the data representing one or more physiological metrics includes data indicative of relative condition of endothelium of the human body.

4 . The method of claim 1 , further comprising:

determining medical condition data indicating one or more medical conditions of the human body based on the at least one algorithm; and

determining recommendations of responsive treatment based on the one or more medical conditions.

5 . The method of claim 4 , wherein determining the medical condition data comprises:

assessing vascular circulation based on stored indication data that correlates particular signals with any one or more of: heart failure, cardiac myopathy, cardiac hypertrophy, enlarged heart, or use of ventricular assisted devices.

6 . The method of claim 1 , wherein performing the analysis further comprises:

determining whether the number of vascular waveforms represents an increase or decrease in the number of vascular waveforms; and

for each of the number of vascular waveforms, determining one or more changes selected from a set of changes that consists of:

a change in blood velocity;

a change in width of waveform; and

a change in blood volume.

7 . The method of claim 1 , wherein the elasticity of the one or more blood vessels is determined based on a bidirectional waveform analysis.

8 . The method of claim 1 , wherein the one or more physiological metrics include at least one of blood pressure, EKG, and spirometry.

9 . The method of claim 1 , wherein the one or more changes include a change representing a blood glucose measure.

10 . The method of claim 1 , wherein the one or more sensors are coupled to the at least one portable physiological measuring device.

11 . The method of claim 1 , wherein the output records comprise any of: a status report on vascular function; a list of options for medical intervention in a patient based on medical standards of practice based on one or more medical indications represented in the vascular performance data; reports or recommendations suggesting sepsis, hypertension, hypotension, or respiratory dysfunction; a protocol for disease intervention; a protocol for nutrition; a protocol for exercise; a protocol for sports performance; a protocol for patient lifestyle or changes in lifestyle; a protocol for patient stress management; a protocol for supplements or medications; a report of recommendations describing nutrition, exercise, supplements, and medications.

12 . A non-transitory computer-readable medium comprising one or more sequences of instructions which when executed using one or more processors cause the one or more processors to perform:

receiving, from at least one portable physiological measuring device configured for temporary attachment to a human body, data representing one or more physiological metrics of the body;

receiving, from one or more sensors configured for temporary attachment to peripheral artery locations of the body, vascular performance data for the body;

determining, by a portable signal measuring device, elasticity of one or more blood vessels based on the vascular performance data received from the one or more sensors;

inputting the data representing the physiological metrics and the elasticity of the one or more blood vessels to at least one algorithm;

performing, by the at least one algorithm, an analysis based on the physiological metrics and the elasticity of the one or more blood vessels;

wherein performing the analysis comprises:

determining one or more changes in the one or more physiological metrics;

wherein the one or more changes include one or more positive changes or one or more negative changes;

determining whether the one or more changes indicate an immediate physiological response or a delayed physiological response;

determining a number of vascular waveforms represented in the vascular performance data; and

based at least in part on the vascular waveforms, determining an interpretation of severity of the one or more changes;

generating and providing output records comprising one or more recommendations of responsive treatment, reports, animations, or figures based at least in part on the analysis.

13 . The computer-readable medium of claim 12 , wherein the one or more sequences of instructions which when executed using the one or more processors cause the one or more processors to perform:

determining medical condition data indicating one or more medical conditions of the body based on the at least one algorithm, wherein determining the medical condition data comprises assessing vascular circulation based on stored indication data that correlates particular signals with any one or more of: heart failure, cardiac myopathy, cardiac hypertrophy, enlarged heart, or use of ventricular assisted devices; and

determining recommendations of responsive treatment based on the one or more medical conditions.

14 . The computer-readable medium of claim 12 , wherein performing the analysis comprises performing assessments of one or more of: vascular circulation, cardiac arrhythmia, extra beats, or premature ventricular contractions.

15 . The computer-readable medium of claim 12 , wherein the physiological measuring device comprises an electrocardiogram EKG apparatus, and wherein performing the analysis comprises correlating EKG data with data.

16 . The computer-readable medium of claim 12 , wherein receiving the data representing the one or more physiological metrics comprises receiving from one or more of any of the following: an infrared, crystal technology, or light-based physiological monitor; a sensor configured for use with augmented reality technology; an auto-fluorescence sensor; a blood pressure sensor; a pulse sensor; a respiratory rate sensor comprising one or more chest patches, wrist patches, and/or chest straps; a body temperature sensor; an oxygen absorption sensor; a carbon dioxide sensor; a nitric oxide sensor; a blood glucose sensor; a sensor of electrolytes, nutrients in circulation, or other metrics; one or more contact lenses configured to measure capillary blood flow; a flow meter; a spirometer; a mouthpiece.

17 . The computer-readable medium of claim 12 , wherein the output records comprise any of: a status report on vascular function; a list of options for medical intervention in a patient based on medical standards of practice based on one or more medical indications represented in the vascular performance data; reports or recommendations suggesting sepsis, hypertension, hypotension, or respiratory dysfunction; a protocol for disease intervention; a protocol for nutrition; a protocol for exercise; a protocol for sports performance; a protocol for patient lifestyle or changes in lifestyle; a protocol for patient stress management; a protocol for supplements or medications; a report of recommendations describing nutrition, exercise, supplements, and medications.

18 . The computer-readable medium of claim 12 , wherein the elasticity of the one or more blood vessels is determined based on a bidirectional waveform Doppler ultrasound analysis.

19 . The computer-readable medium of claim 12 , wherein the one or more changes include a change representing a blood glucose measure.

20 . The computer-readable medium of claim 12 , wherein the one or more sensors are coupled to the at least one portable physiological measuring device.

Continuity (7)

References Cited (68)