IP Library Granted Patent US 12,651,659
Granted Patent B2
US 12,651,659 · App. 18/137,183 · Granted Jun 9, 2026

Insulin adaptation and safety monitoring for sick day management

Inventor: Rangarajan Narayanaswami (Weston, MA)
Assignee: INSULET CORPORATION
G16H20/10A61B5/14532A61B5/14546A61M5/1723A61M5/14248A61M2202/0486A61M2205/3303A61M2205/502A61M2205/52A61M2230/201
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,651,659
App. No.
18/137,183
Granted
Jun 9, 2026
Kind
B2
Abstract

Disclosed are an apparatus, system, processes, and techniques for adapting drug delivery and monitoring a user's safety when the user is experiencing a sick day. A processor may be operable to provide a graphical user interface that presents a sickness mode prompt for a user to indicate that the user or another person with diabetes is sick. The graphical user interface may present symptoms from which a user may select. Based on the selection of symptoms, glucose measurement values, and/or ketone measurement values, a response to the user's indication of sickness may be provided.

Claims (40)

1 . A controller of a drug delivery system, comprising:

a processor operable to execute programming instructions;

a user interface including a display and user input circuitry;

a memory operable to store the programming instructions; and

a communication circuitry coupled to the processor operable to receive and transmit wireless communication signals, wherein the processor, when executing the programming instructions, is operable to:

receive an indication that a user is experiencing a sickness;

based on the indication, adjust one or more settings of a medication delivery algorithm;

cause delivery of a liquid drug based on the adjusted one or more settings;

evaluate a glucose measurement value with respect to a hyperglycemic threshold;

evaluate a ketone measurement value with respect to a selected ketone level threshold of a plurality of ketone level thresholds; and

increase a total daily insulin value based on the evaluation of the glucose measurement value and the evaluation of the ketone measurement value.

2 . The controller of claim 1 , wherein the processor is operable to:

generate a prompt with a list of symptoms of the sickness; and

receive a selection from the user from among the list of symptoms.

3 . The controller of claim 1 , wherein the processor is operable to:

receive a glucose measurement value from a glucose sensor via the communication circuitry, or

receive a ketone level reading from a ketone sensor via the communication circuitry.

4 . The controller of claim 1 , wherein the processor, when evaluating the ketone measurement value with respect to the selected ketone level threshold from the plurality of ketone level thresholds, is operable to:

determine whether the ketone measurement value is greater than the selected ketone level threshold; and

based on the determination, generate a ketone measurement value indication.

5 . The controller of claim 1 , wherein the processor is further operable to:

adapting a basal dosage, bolus dosage, and a delivery schedule based on the increased total daily insulin.

6 . The controller of claim 5 , wherein the processor, when adapting the basal dosage, is operable to:

increase the basal dosage by a selected percentage of a nominal basal dosage setting.

7 . The controller of claim 6 , wherein the processor, when evaluating the ketone measurement value with respect to the selected ketone level threshold from the plurality of ketone level thresholds, is operable to:

determine whether the ketone measurement value is greater than the selected ketone level threshold; and

based on the determination, generate a ketone measurement value indication.

8 . The controller of claim 6 , wherein the processor, when adapting the bolus dosage, is operable to:

increase the bolus dosage based on a bolus delivery calculation that utilizes the increased total daily insulin.

9 . A controller of a drug delivery system, comprising:

a processor operable to execute programming instructions;

a user interface including a display and user input circuitry;

a memory operable to store the programming instructions; and

a communication circuitry coupled to the processor operable to receive and transmit wireless communication signals, wherein the processor, when executing the programming instructions, is operable to:

receive an indication that a user is experiencing a sickness;

based on the indication, adjust one or more settings of a medication delivery algorithm;

cause delivery of a liquid drug based on the adjusted one or more settings;

evaluate a glucose measurement value with respect to a hypoglycemic threshold range;

evaluate a ketone measurement value with respect to a selected ketone level threshold of a plurality of ketone level thresholds; and

reduce a total daily insulin value based on the evaluation of the glucose measurement value and the evaluation of the ketone measurement value.

Assignments (2)
SECURITY AGREEMENT SUPPLEMENT Recorded Sep 7, 2023
From: INSULET CORPORATION
To: MORGAN STANLEY SENIOR FUNDING, INC., AS COLLATERAL AGENT
Reel/Frame 064840/0181 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 25, 2023
From: NARAYANASWAMI, RANGARAJAN
To: INSULET CORPORATION
Reel/Frame 063426/0512 →