Sensing cannula systems
Disclosed cannula systems can detect the tissue type within which the cannula tip is located in real time using electrodes adjacent the cannula tip. The sensing cannula system can differentiate when the cannula tip is in adipose tissue or muscle based on electrical impedance. The system can be used in fat grafting and liposuction procedures, for example. An operator can detect if the cannula tip enters muscle by watching for an indicator light or audible alarm that is automatically activated by the device based on a change in sensed impedance. The device may also stop the flow of fat through a pump halting injection into the sub-muscular space.
1. A device comprising a metal cannula with two electrodes at or near a tip of the cannula operable to measure impedance of tissue adjacent to the tip of the cannula, wherein the cannula is operable as a first electrode of the two electrodes and a removable sheath positionable over the cannula comprises a second electrode of the two electrodes, the removable sheath further comprising an electrical insulation layer between the cannula and the second electrode that electrically insulates the cannula from the second electrode, wherein an impedance sensing system is electrically coupled to the cannula and electrically coupled to the second electrode to measure impedance of tissue adjacent the tip of the cannula, and wherein the removable sheath comprises a conductor that makes electrical contact with the cannula when the removable sheath is positioned over the cannula.
2. The device of claim 1 , wherein the tip of the cannula is exposed and serves as the first electrode.
3. The device of claim 1 , further comprising an audible or visual indicator that notifies a user when a predetermined impedance threshold value is detected.
4. The device of claim 1 , further comprising a valve or clamp configured to close the cannula to stop flow of fat or other material through the cannula based on a measured impedance value.
5. A method comprising measuring impedance of biological material adjacent to the cannula of the device of claim 1 , and determining an identity of the material based on the measured impedance.
6. The method of claim 5 , further comprising closing or opening the cannula based on the determined identity of the material adjacent to the cannula.
7. The method of claim 5 , further comprising preventing material from flowing through the cannula based on the determined identity of the material adjacent to the cannula.
8. The method of claim 7 , further comprising closing a valve or stopping a pump to prevent material from flowing through the cannula.
9. A system comprising:
a cannula having a distal tip and operable as a first electrode;
a removable sheath positioned over the cannula, the sheath comprising a second electrode positioned adjacent a distal end of the sheath and an electrical insulation layer between the cannula and the second electrode, wherein the electrical insulation layer electrically insulates the cannula from the second electrode; and
an impedance sensing system electrically coupled to the cannula and also electrically coupled to the second electrode;
wherein the cannula, the second electrode, and the impedance sensing system are operable to measure impedance of tissue adjacent to the distal tip of the cannula.
10. The system of claim 9 , wherein the sheath comprises a conductor that makes electrical contact with the cannula when the sheath is positioned over the cannula.
11. The system of claim 10 , wherein the conductor is a metallic inner sleeve positionable around the cannula in electrical contact with the cannula.
12. The system of claim 9 , wherein the sheath comprises:
a first electrical conductor that is in electrical contact with the cannula when the sheath is positioned over the cannula and is electrically coupled to the impedance sensing system; and
a second electrical conductor that extends from the second electrode proximally along an axial length of the sheath and is electrically coupled to the impedance sensing system while being electrically insulated from the cannula and the first electrical conductor.
13. The system of claim 9 , further comprising an audible or visual indicator that notifies a user when a predetermined impedance threshold is sensed.
14. The system of claim 9 , further comprising a valve or clamp configured to stop flow of adipose tissue or other material through the cannula based on a measured impedance value.
15. The system of claim 14 , wherein the system comprises a valve, and the valve is actuatable to shut off flow of material through the cannula based on a measured impedance value.
16. The system of claim 14 , wherein the system comprises a clamp;
the system further comprises a syringe coupled to the cannula; and
the clamp is operable to impede motion of a plunger of the syringe based on a measured impedance value.
17. The system of claim 9 , further comprising an array of electrodes on a distal portion of the sheath or the cannula, the array of electrodes being arranged to improve resolution or directionality of impedance sensing.
18. The system of claim 17 , wherein the array of electrodes is arranged linearly along a length of the sheath or cannula and/or circumferentially around the sheath or cannula.
19. The system of claim 9 , wherein the system is operable to perform fat grafting and/or liposuction.
20. The system of claim 9 , wherein the system is operable to distinguish adipose tissue from muscle tissue based on sensed impedance.
21. The system of claim 9 , wherein the system is operable to stop flow of material through the cannula when the system determines that the distal tip of the cannula is adjacent muscle tissue, and operable to allow flow of material through the cannula when the system determines that the distal tip is adjacent adipose tissue.
22. A system comprising:
a cannula having a distal tip and operable as a first electrode;
a removable sheath positioned over the cannula, the sheath comprising a second electrode positioned adjacent a distal end of the sheath and an electrical insulation layer between the cannula and the second electrode, wherein the electrical insulation layer electrically insulates the cannula from the second electrode; and
an impedance sensing system electrically coupled to the cannula and also electrically coupled to the second electrode;
wherein the cannula, the second electrode, and the impedance sensing system are operable to measure impedance of tissue adjacent to the distal tip of the cannula; and
wherein the system further comprises a clamp and a syringe coupled to the cannula, and the clamp is operable to impede motion of a plunger of the syringe based on a measured impedance value to stop flow of adipose tissue or other material through the cannula.