Granted Patent B2

US 12,369,804 · App. 18/162,953 · Granted Jul 29, 2025

Inventor: David He (South San Francisco, CA)

Assignee: Verily Life Sciences LLC

A61B5/02427A61B5/0059A61B5/0205A61B5/02405A61B5/4809A61B5/6808A61B5/721A61F13/42A61F13/49007A61B5/0816A61B2503/04A61B2562/0219A61B2562/0238A61F2013/422

Abstract

Claims (81)

1. A method comprising:

obtaining a first plurality of measurements of light, wherein obtaining the first plurality of measurements of light comprises, for each measurement:

causing a first light source to transmit a pulse of light through an article to an area of skin, wherein the first light source is positioned in a first configuration; and

determining a first measurement of light returned from the article;

responsive to determining that an energy level of the first plurality of measurements of light is lower than a threshold obtaining, a second plurality of measurements of light, wherein obtaining the second plurality of measurements of light comprises, for each measurement:

causing a second light source to transmit a second pulse of light through the article to the area of skin, wherein the second light source is positioned in a second configuration that is different from the first configuration; and

obtaining a second measurement of light returned from the article;

determining, from the first plurality of measurements of light and the second plurality of measurements of light, a periodic change in an amplitude; and

identifying the periodic change in amplitude as a heart rate based on the periodic change in amplitude.

2. The method of claim 1 , further comprising:

removing an ambient light signal from one or more of the first plurality of measurement of light and the second plurality of measurement of light.

3. The method of claim 1 , further comprising:

obtaining, via an inertial measurement device, a plurality of data samples; and

responsive to determining that the heart rate is below a heart rate threshold, determining, from the plurality of data samples, that an infant wearing the article is asleep in a moving carrier.

4. The method of claim 1 , further comprising:

determining a rate of change in one or more of (i) the periodic change in amplitude or (ii) an envelope modulation of the first plurality of measurements of light and the second plurality of measurements of light; and

identifying a respiratory rate as equal to the rate of change.

5. The method of claim 1 , wherein identifying the periodic change in amplitude comprises:

obtaining a plurality of frequency components by transforming one or more of the first plurality of measurements of light and the second plurality of measurements of light into a frequency domain; and

identifying, from the plurality of frequency components, a component comprising a highest energy content.

6. The method of claim 1 , wherein identifying the periodic change in amplitude comprises:

obtaining, via an inertial measurement device, a plurality of data samples;

determining that the plurality of data samples indicate movement of a wearer wearing the article;

correlating the plurality of data samples with one or more of the first plurality of measurements of light and the second plurality of measurements of light; and

removing, from one or more of the first plurality of measurements of light and the second plurality of measurements of light, a contribution of the movement.

7. The method of claim 1 , further comprising:

adjusting one or more of the first plurality of measurements of light and the second plurality of measurements of light to compensate for a contribution of the article based on one or more known properties of the article.

8. A system comprising:

a non-transitory computer-readable medium storing computer-executable program instructions; and

a processing device communicatively coupled to the non-transitory computer-readable medium for executing the computer-executable program instructions, wherein executing the computer-executable program instructions configures the processing device to perform operations comprising:

obtaining a first plurality of normalized measurements of light, wherein obtaining the first plurality of measurements of light comprises, for each measurement:

causing a first light source to transmit a pulse of light through an article to an area of skin, wherein the first light source is positioned in a first configuration;

determining a first measurement of light returned from the article;

responsive to determining that an energy level of the first plurality of measurements of light is lower than a threshold obtaining, a second plurality of measurements of light, wherein obtaining the second plurality of measurements of light comprises, for each measurement:

causing a second light source to transmit a second pulse of light through the article to the area of skin, wherein the second light source is positioned in a second configuration that is different from the first configuration; and

obtaining a second measurement of light returned from the article;

determining, from the first plurality of measurements of light and the second plurality of measurements of light, a periodic change in an amplitude; and

identifying the periodic change in amplitude as a heart rate based on the periodic change in amplitude.

9. The system of claim 8 , wherein executing the computer-executable program instructions configures the processing device to perform operations comprising:

removing an ambient light signal from one or more of the first plurality of measurement of light and the second plurality of measurement of light.

10. The system of claim 8 , wherein executing the computer-executable program instructions configures the processing device to perform operations comprising:

obtaining, via an inertial measurement device, a plurality of data samples; and

responsive to determining that the heart rate is below a heart rate threshold, determining, from the plurality of data samples, that an infant wearing the article is asleep in a moving carrier.

11. The system of claim 8 , wherein executing the computer-executable program instructions configures the processing device to perform operations comprising:

determining a rate of change in one or more of (i) the periodic change in amplitude or (ii) an envelope modulation of the first plurality of measurements of light and the second plurality of measurements of light; and

identifying a respiratory rate as equal to the rate of change.

12. The system of claim 8 , wherein identifying the periodic change in amplitude comprises:

obtaining a plurality of frequency components by transforming one or more of the first plurality of measurements of light and the second plurality of measurements of light into a frequency domain; and

identifying, from the plurality of frequency components, a component comprising a highest energy content.

13. The system of claim 8 , wherein identifying the periodic change in amplitude comprises:

obtaining, via an inertial measurement device, a plurality of data samples;

determining that the plurality of data samples indicate movement of a wearer wearing the article;

correlating the plurality of data samples with one or more of the first plurality of measurements of light and the second plurality of measurements of light; and

removing, from one or more of the first plurality of measurements of light and the second plurality of measurements of light, a contribution of the movement.

14. A non-transitory computer-readable storage medium storing computer-executable program instructions, wherein when executed by a processing device, the computer-executable program instructions cause the processing device to perform operations comprising:

obtaining a first plurality of normalized measurements of light, wherein obtaining the first plurality of measurements of light comprises, for each measurement:

causing a first light source to transmit a pulse of light through an article to an area of skin, wherein the first light source is positioned in a first configuration;

determining a first measurement of light returned from the article;

responsive to determining that an energy level of the first plurality of measurements of light is lower than a threshold obtaining, a second plurality of measurements of light, wherein obtaining the second plurality of measurements of light comprises, for each measurement:

causing a second light source to transmit a second pulse of light through the article to the area of skin, wherein the second light source is positioned in a second configuration that is different from the first configuration; and

obtaining a second measurement of light returned from the article;

determining, from the first plurality of measurements of light and the second plurality of measurements of light, a periodic change in an amplitude; and

identifying the periodic change in amplitude as a heart rate based on the periodic change in amplitude.

15. The non-transitory computer-readable storage medium of claim 14 , wherein when executed by a processing device, the computer-executable program instructions cause the processing device to perform operations comprising:

removing an ambient light signal from one or more of the first plurality of measurement of light and the second plurality of measurement of light.

16. The non-transitory computer-readable storage medium of claim 14 , wherein when executed by a processing device, the computer-executable program instructions cause the processing device to perform operations comprising:

obtaining, via an inertial measurement device, a plurality of data samples; and

responsive to determining that the heart rate is below a heart rate threshold, determining, from the plurality of data samples, that an infant wearing the article is asleep in a moving carrier.

17. The non-transitory computer-readable storage medium of claim 14 , wherein when executed by a processing device, the computer-executable program instructions cause the processing device to perform operations comprising:

determining a rate of change in one or more of (i) the periodic change in amplitude or (ii) an envelope modulation of the first plurality of measurements of light and the second plurality of measurements of light; and

identifying a respiratory rate as equal to the rate of change.

18. The non-transitory computer-readable storage medium of claim 14 , wherein identifying the periodic change in amplitude comprises:

obtaining a plurality of frequency components by transforming one or more of the first plurality of measurements of light and the second plurality of measurements of light into a frequency domain; and

identifying, from the plurality of frequency components, a component comprising a highest energy content.

19. The non-transitory computer-readable storage medium of claim 14 , wherein identifying the periodic change in amplitude comprises:

obtaining, via an inertial measurement device, a plurality of data samples;

determining that the plurality of data samples indicate movement of a wearer wearing the article;

correlating the plurality of data samples with one or more of the first plurality of measurements of light and the second plurality of measurements of light; and

removing, from one or more of the first plurality of measurements of light and the second plurality of measurements of light, a contribution of the movement.

20. The non-transitory computer-readable storage medium of claim 14 , wherein when executed by a processing device, the computer-executable program instructions cause the processing device to perform operations comprising:

adjusting one or more of the first plurality of measurements of light and the second plurality of measurements of light to compensate for a contribution of the article based on one or more known properties of the article.

Assignments (2)

Continuity (3)

References Cited (185)