IP Library Granted Patent US 12,048,490
Granted Patent B2
US 12,048,490 · App. 18/180,190 · Granted Jul 30, 2024

Systems and methods for correction of artificial deformation in anatomic modeling

Inventors: Leo John Grady (Darien, CT); Michiel Schaap (Oegstgeest, NL); Sophie Khem (San Francisco, CA); Sarah Wilkes (San Mateo, CA); Ying Bai (Belmont, CA)
Assignee: HeartFlow, Inc.
A61B34/10G06F18/22G06F18/24G06F30/20G06T7/0012G06T7/60G06T7/70G09B9/00G09B23/303G16B5/00G16H50/50A61B6/5258A61B2034/105G06T13/20G06T2207/10004G06T2207/30101G06T2207/30104
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Quick Facts
Patent No.
US 12,048,490
App. No.
18/180,190
Granted
Jul 30, 2024
Kind
B2
Abstract

Systems and methods are disclosed for correcting for artificial deformations in anatomical modeling. One method includes obtaining an anatomic model; obtaining information indicating a presence of an artificial deformation of the anatomic model; identifying a portion of the anatomic model associated with the artificial deformation; estimating a non-deformed local area corresponding to the portion of the anatomic model; and modifying the portion of the anatomic model associated with the artificial deformation, based on the estimated non-deformed local area.

Claims (32)

1. A computer-implemented method of correcting anatomical modeling, the method comprising:

obtaining an anatomic model, wherein the anatomic model is a blood vessel model;

obtaining information indicating a presence of an artificial deformation of the anatomic model, wherein the artificial deformation is based on at least one of a misregistration, a motion artifact, or myocardial bridging;

identifying a portion of the anatomic model associated with the artificial deformation;

estimating a non-deformed local area corresponding to the portion of the anatomic model, wherein the local area includes an estimated area for a non-deformed blood vessel, wherein estimating the non-deformed local area is determined by either: (1) determining a constant radius centered on a centerline of the blood vessel model, (2) identifying a radius of a proximal region proximal to the artificial deformation and a radius of a distal region distal to the artificial deformation, and estimating the non-deformed local area for the portion of the anatomic model based on a radius interpolated between the radius of the proximal region and the radius of distal region, or (3) based on a radius obtained based on a probability distribution of blood vessel radii or a database of patient data; and

modifying the portion of the anatomic model associated with the artificial deformation, based on the estimated non-deformed local area.

2. The method of claim 1 , further including:

performing one or more simulations using the modified vessel model.

3. The method of claim 1 , wherein the information indicating the presence of the artificial deformation is obtained based on a user input.

4. The method of claim 1 , wherein the information indicating the presence of the artificial deformation is obtained based on a computation between one or more images, measuring an image artifact, employing a segmentation algorithm, or a combination thereof.

5. A system for correcting anatomical modeling, the system comprising:

a data storage device storing instructions for correcting anatomical modeling; and

a processor configured to execute the instructions to perform a method including:

obtaining an anatomic model, wherein the anatomic model is a blood vessel model;

obtaining information indicating a presence of an artificial deformation of the anatomic model, wherein the artificial deformation is based on at least one of a misregistration, a motion artifact, or myocardial bridging;

identifying a portion of the anatomic model associated with the artificial deformation;

estimating a non-deformed local area corresponding to the portion of the anatomic model, wherein the local area includes an estimated area for a non-deformed blood vessel, wherein estimating the non-deformed local area is determined by either: (1) determining a constant radius centered on a centerline of the blood vessel model, (2) identifying a radius of a proximal region proximal to the artificial deformation and a radius of a distal region distal to the artificial deformation, and estimating the non-deformed local area for the portion of the anatomic model based on a radius interpolated between the radius of the proximal region and the radius of distal region, or (3) based on a radius obtained based on a probability distribution of blood vessel radii or a database of patient data; and

modifying the portion of the anatomic model associated with the artificial deformation, based on the estimated non-deformed local area.

6. The system of claim 5 , further including:

performing one or more simulations using the modified vessel model.

7. The system of claim 5 , wherein the information indicating the presence of the artificial deformation is obtained based on a user input.

8. The system of claim 5 , wherein the information indicating the presence of the artificial deformation is obtained based on a computation between one or more images, measuring an image artifact, employing a segmentation algorithm, or a combination thereof.

9. A non-transitory computer readable medium for use on a computer system containing computer-executable programming instructions for performing a method of correcting anatomical modeling, the method comprising:

obtaining an anatomic model, wherein the anatomic model is a blood vessel model;

obtaining information indicating a presence of an artificial deformation of the anatomic model, wherein the artificial deformation is based on at least one of a misregistration, a motion artifact, or myocardial bridging;

identifying a portion of the anatomic model associated with the artificial deformation;

estimating a non-deformed local area corresponding to the portion of the anatomic model, wherein the local area includes an estimated area for a non-deformed blood vessel, wherein estimating the non-deformed local area is determined by either: (1) determining a constant radius centered on a centerline of the blood vessel model, (2) identifying a radius of a proximal region proximal to the artificial deformation and a radius of a distal region distal to the artificial deformation, and estimating the non-deformed local area for the portion of the anatomic model based on a radius interpolated between the radius of the proximal region and the radius of distal region, or (3) based on a radius obtained based on a probability distribution of blood vessel radii or a database of patient data; and

modifying the portion of the anatomic model associated with the artificial deformation, based on the estimated non-deformed local area.

10. The non-transitory computer readable medium of claim 9 , further including:

performing one or more simulations using the modified vessel model.

11. The non-transitory computer readable medium of claim 9 , wherein the information indicating presence of the artificial deformation is based on a computation between one or more images, measuring an image artifact, employing a segmentation algorithm, or a combination thereof.

12. The non-transitory computer readable medium of claim 9 , wherein the information indicating the presence of the artificial deformation is obtained based on a user input.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Sep 11, 2025
From: HAYFIN SERVICES LLP
To: HEARTFLOW, INC.
Reel/Frame 072876/0775 →
SECURITY INTEREST Recorded Jun 18, 2024
From: HEARTFLOW, INC.
To: HAYFIN SERVICES LLP
Reel/Frame 067775/0966 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 8, 2023
From: GRADY, LEO JOHN; SCHAAP, MICHIEL; KHEM, SOPHIE; WILKES, SARAH; BAI, YING
To: HEARTFLOW, INC.
Reel/Frame 062925/0807 →
Cited By (6)
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