IP Library Granted Patent US 11,925,441
Granted Patent B1
US 11,925,441 · App. 18/189,849 · Granted Mar 12, 2024

Techniques for determining blood pressure based on morphological features of pulses preliminary class

Inventors: Antti Aleksi Rantanen (Oulu, FI); Juha Pekka Pärkkä (Lempäälä, FI); Heli Tuulia Koskimäki (Oulu, FI); Olli Petteri Heikkinen (Oulu, FI); Jukka Tapani Mäkinen (Oulu, FI); Jussi Petteri Järvelä (Kempele, FI); Hannu Hermanni Koivisto (Oulu, FI); Pauli Juhani Ohukainen (Oulu, FI); Juha-Pekka Syrjälä (Oulu, FI)
Assignee: Oura Health Oy
A61B5/021A61B5/6802A61B5/742A61B5/7475A61B5/02438A61B2560/0223
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Quick Facts
Patent No.
US 11,925,441
App. No.
18/189,849
Granted
Mar 12, 2024
Kind
B1
Abstract

Methods, systems, and devices for determining blood pressure based on morphological features of pulses are described. A system may include a wearable device that uses one or more light emitting components configured to emit light, one or more photodetectors configured to receive light, and a controller that couples the one or more light emitting components to the one or more photodetectors. The wearable device may transmit lights associated with multiple wavelengths, and acquire photoplethysmogram (PPG) data that includes one or more PPG waveforms associated with the respective wavelengths. The system may determine respective sets of morphological features associated with each of the PPG waveforms based on systolic and diastolic peaks corresponding to the heartbeat of the user. The system may determine one or more blood pressure metrics for the user based at least in part on a comparison of the respective sets of morphological features.

Claims (50)

1. A wearable device for measuring blood pressure, comprising:

one or more light-emitting components configured to emit light associated with at least a first wavelength and a second wavelength;

one or more photodetectors configured to receive light emitted by the one or more light-emitting components; and

a controller communicatively coupled to the one or more light-emitting components and the one or more photodetectors, the controller configured to:

transmit, during a time interval including a heartbeat of a user and using the one or more light-emitting components, first light associated with the first wavelength and second light associated with the second wavelength;

acquire photoplethysmogram (PPG) data from the user based at least in part on receiving the first light and the second light via the one or more photodetectors, the PPG data comprising at least a first PPG waveform acquired using the first light associated with the first wavelength and a second PPG waveform acquired using the second light associated with the second wavelength;

determine a second derivative of the first PPG waveform associated with the first wavelength, and an additional second derivative of the second PPG waveform associated with the second wavelength;

determine a peak of the second derivative corresponding to a systolic peak of the first PPG waveform, and a peak of the additional second derivative corresponding to a systolic peak of the second PPG waveform;

determine a first set of morphological features associated with the first PPG waveform based at least in part on the systolic peak and a diastolic peak corresponding to the heartbeat within the first PPG waveform, wherein the first set of morphological features comprise the peak of the second derivative of the first PPG waveform;

determine a second set of morphological features associated with the second PPG waveform based at least in part on the systolic peak and a diastolic peak corresponding to the heartbeat within the second PPG waveform, wherein the second set of morphological features comprise the peak of the additional second derivative of the second PPG waveform; and

determine a blood pressure metric for the user based at least in part on a comparison of the first set of morphological features and the second set of morphological features and based at least in part on a delay between the peak of the second derivative of the first PPG waveform and the peak of the additional second derivative of the second PPG waveform.

2. The wearable device of claim 1 , wherein the controller is further configured to:

determine a baseline blood pressure metric associated with the user;

determine a difference between the baseline blood pressure metric and the blood pressure metric; and

cause a graphical user interface of a user device to display information associated with the difference between the baseline blood pressure metric and the blood pressure metric.

3. The wearable device of claim 1 , wherein the controller is further configured to:

determine a correlation coefficient between the first PPG waveform and the second PPG waveform based at least in part on the comparison of the first set of morphological features and the second set of morphological features, wherein the blood pressure metric is based at least in part on the correlation coefficient.

4. The wearable device of claim 3 , wherein the first wavelength comprises a first wavelength range associated with infrared light, and wherein the second wavelength comprises a second wavelength range associated with red light.

5. The wearable device of claim 1 , wherein the first wavelength comprises a first wavelength range associated with infrared light, red light, or both, and wherein the second wavelength comprises a second wavelength range associated with green light.

6. The wearable device of claim 1 , wherein the controller is further configured to:

determine a delay between the systolic peaks of the first PPG waveform and the second PPG waveform, wherein the blood pressure metric is based at least in part on the delay.

7. The wearable device of claim 6 , wherein the first wavelength comprises a first wavelength range associated with red light, and wherein the second wavelength comprises a second wavelength range associated with green light.

8. The wearable device of claim 1 , wherein the PPG data is acquired during a time interval that a pressure between the wearable device and a tissue of the user is changed from a first pressure to a second pressure, wherein the first set of morphological features and the second set of morphological features comprise responses of the first PPG waveform and the second PPG waveform, respectively, to the change from the first pressure to the second pressure.

9. The wearable device of claim 8 , wherein the controller is further configured to:

cause a graphical user interface of a user device to display instructions for the user to selectively change the pressure from the first pressure to the second pressure during the time interval, wherein acquiring the PPG data throughout the time interval is based at least in part on the instructions.

10. The wearable device of claim 1 , wherein the controller is further configured to:

acquire physiological data from the user via the wearable device, the physiological data comprising at least the PPG data and acceleration data associated with movement of the user; and

selectively adjust the blood pressure metric based at least in part on the acceleration data.

11. The wearable device of claim 1 , wherein the wearable device comprises a wearable ring device.

12. The wearable device of claim 1 ,

wherein the first set of morphological features comprises an amplitude of the systolic peak of the first PPG waveform, the diastolic peak of the first PPG waveform, or both, and

wherein the second set of morphological features comprises a amplitudeof the systolic peak of the second PPG waveform, the diastolic peak of the second PPG waveform, or both.

13. A method for measuring blood pressure comprising:

acquiring photoplethysmogram (PPG) data from a user using a wearable device, the PPG data collected during a time interval including a heartbeat of the user, the PPG data comprising at least a first PPG waveform acquired using first light associated with a first wavelength and a second PPG waveform acquired using second light associated with a second wavelength;

determining a second derivative of the first PPG waveform associated with the first wavelength, and an additional second derivative of the second PPG waveform associated with the second wavelength;

determine a peak of the second derivative corresponding to a systolic peak of the first PPG waveform, and a peak of the additional second derivative corresponding to a systolic peak of the second PPG waveform;

determining a first set of morphological features associated with the first PPG waveform based at least in part on the systolic peak and a diastolic peak corresponding to the heartbeat within the first PPG waveform, wherein the first set of morphological features comprise the first peak of the second derivative of the first PPG waveform;

determining a second set of morphological features associated with the second PPG waveform based at least in part on the systolic peak and a diastolic peak corresponding to the heartbeat within the second PPG waveform, wherein the second set of morphological features comprise the second peak of the additional second derivative of the second PPG waveform; and

determining a blood pressure metric for the user based at least in part on a comparison of the first set of morphological features and the second set of morphological features and based at least in part on a delay between the peak of the second derivative of the first PPG waveform and the peak of the additional second derivative of the second PPG waveform.

14. The method of claim 13 , further comprising:

determining a baseline blood pressure metric associated with the user;

determining a difference between the baseline blood pressure metric and the blood pressure metric; and

causing a graphical user interface of a user device to display information associated with the difference between the baseline blood pressure metric and the blood pressure metric.

15. The method of claim 13 , further comprising:

determining a correlation coefficient between the first PPG waveform and the second PPG waveform based at least in part on the comparison of the first set of morphological features and the second set of morphological features, wherein the blood pressure metric is based at least in part on the correlation coefficient.

16. The method of claim 15 , wherein acquiring the PPG data comprises:

transmitting the first light and the second light using a light-emitting component of the wearable device;

receiving the first light and the second light using a photodetector of the wearable device; and

generating the first PPG waveform and the second PPG waveform based at least in part on receiving the first light and the second light, respectively, via the photodetector.

17. The method of claim 15 , wherein the first wavelength comprises a first wavelength range associated with infrared light, and wherein the second wavelength comprises a second wavelength range associated with red light.

Assignments (4)
RELEASE OF SECURITY INTERESTS IN PATENTS AND TRADEMARKS AT REEL/FRAME NO. 66986/0101 Recorded May 16, 2025
From: CRG SERVICING LLC, AS ADMINISTRATIVE AGENT
To: OURA HEALTH OY
Reel/Frame 071297/0305 →
SECURITY INTEREST Recorded May 16, 2025
From: OURA HEALTH OY; OURARING INC.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 071302/0800 →
SECURITY INTEREST Recorded Apr 2, 2024
From: OURA HEALTH OY
To: CRG SERVICING LLC, AS ADMINISTRATIVE AGENT
Reel/Frame 066986/0101 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 5, 2023
From: RANTANEN, ANTTI ALEKSI; PÄRKKÄ, JUHA PEKKA; KOSKIMÄKI, HELI TUULIA; HEIKKINEN, OLLI PETTERI; MÄKINEN, JUKKA TAPANI; JÄRVELÄ, JUSSI PETTERI; KOIVISTO, HANNU HERMANNI; OHUKAINEN, PAULI JUHANI; SYRJÄLÄ, JUHA-PEKKA
To: OURA HEALTH OY
Reel/Frame 065136/0841 →
Cited By (3)
US 12,405,211 US 12,484,815 US 12,678,059