IP Library Granted Patent US 11,779,627
Granted Patent B1
US 11,779,627 · App. 18/205,792 · Granted Oct 10, 2023

Curcumin compositions and methods of use as an NK3 antagonist

Inventors: James R. Komorowski (Trumbull, CT); Sarah Sylla (Brooklyn, NY)
Assignee: JDS THERAPEUTICS, LLC
A61K36/9066A61K31/26A61K36/82A61P15/12
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,779,627
App. No.
18/205,792
Granted
Oct 10, 2023
Kind
B1
Abstract

Disclosed herein are compositions for treating, ameliorating, preventing, or reducing the symptoms associated with menopause and/or hot flashes. The compositions disclosed herein comprise a curcumin composition, a green tea extract composition, and a phycocyanin composition that act as neurokinin 3 receptor antagonists. Also described herein are methods utilizing the aforementioned compositions.

Claims (12)

1. A method of treating, ameliorating, preventing, or reducing symptoms associated with menopause in a subject, the method comprising:

identifying that the subject is experiencing or will experience symptoms associated with menopause; and

administering a combination composition to the subject, wherein the combination composition comprises a neurokinin 3 (NK3) antagonist containing a combination of an amount of the curcumin composition, an amount of the green tea extract composition, and an amount of the phycocyanin composition in a synergistic ratio.

2. The method of claim 1 , wherein the amount of the curcumin composition is about 100 mg to about 750 mg.

3. The method of claim 1 , wherein the amount of the green tea extract composition is about 100 mg to about 500 mg.

4. The method of claim 1 , wherein the amount of the phycocyanin composition is about 100 mg.

5. A method of treating, ameliorating, preventing, or reducing effects of hot flashes in a subject, the method comprising:

identifying that the subject is experiencing or will experience effects of hot flashes; and

administering a combination composition to the subject, wherein the combination composition comprises a NK3 antagonist containing a combination of an amount of the curcumin composition, an amount of the green tea extract composition, and an amount of the phycocyanin composition in a synergistic ratio.

6. The method of claim 5 , wherein the amount of the curcumin composition is about 100 mg to about 750 mg.

7. The method of claim 5 , wherein the amount of the green tea extract composition is about 100 mg to about 500 mg.

8. The method of claim 5 , wherein the amount of the phycocyanin composition is about 100 mg.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 29, 2023
From: JDS THERAPEUTICS, LLC
To: BONAFIDE HEALTH, LLC
Reel/Frame 065072/0787 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 7, 2023
From: KOMOROWSKI, JAMES R.; SYLLA, SARAH
To: JDS THERAPEUTICS, LLC
Reel/Frame 063886/0315 →
Continuity (2)
Division 17968788 · Oct 18, 2022
Provisional Application 63278989 · Nov 12, 2021