IP Library Granted Patent US 12,442,880
Granted Patent B2
US 12,442,880 · App. 18/218,006 · Granted Oct 14, 2025

Techniques for dynamic control of a magnetic resonance imaging system

Inventors: Laura Sacolick (Guilford, CT); Jonathan Lowthert (Stamford, CT); Jeremy Christopher Jordan (Cromwell, CT); Hadrien A. Dyvorne (New York, NY)
Assignee: Hyperfine Operations, Inc.
G01R33/543A61B5/055G01R33/385G01R33/445G01R33/546
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Quick Facts
Patent No.
US 12,442,880
App. No.
18/218,006
Granted
Oct 14, 2025
Kind
B2
Abstract

Techniques are described for controlling components of a Magnetic Resonance Imaging (MRI) system with a single controller, such as a Field Programmable Gate Array (FPGA), by dynamically instructing the controller to issue commands to the components using a processor coupled to the controller. According to some aspects, the controller may issue commands to the components of the MRI system whilst actively receiving commands from the processor to be later issued to the components.

Claims (36)

1. A magnetic resonance imaging (MRI) system, comprising:

one or more components configured to acquire magnetic resonance data, the one or more components comprising at least one permanent magnet configured to produce a B 0 field that is less than or equal to 0.1 T and greater than or equal to 50 mT;

a first controller; and

at least one processor configured to determine times to issue individual commands from the first controller to the one or more components;

wherein the first controller is configured to control the one or more components to operate in accordance with a first pulse sequence at least in part by:

receiving, from the at least one processor, a sequence of commands for controlling the one or more components to operate in accordance with the first pulse sequence; and

issuing at least one command of the sequence of commands to the one or more components, in accordance with the determined times to issue the at least one command.

2. The MRI system of claim 1 , wherein the first controller is a Field Programmable Gate Array (FPGA).

3. The MRI system of claim 1 , wherein the first controller and the at least one processor are connected via a Universal Serial Bus (USB) connection and the first controller receives commands of the sequence of commands via the USB connection.

4. The MRI system of claim 1 , further comprising a second controller coupled to the first controller and configured to receive data from the one or more components.

5. The MRI system of claim 4 , wherein the second controller is configured to provide the data received from the one or more components to the at least one processor.

6. The MRI system of claim 5 , wherein the second controller is further configured to provide an indication of available memory in the first controller to the at least one processor.

7. The MRI system of claim 4 , wherein the first controller and second controller are synchronized via a common clock signal.

8. The MRI system of claim 1 , wherein the one or more components comprises an RF coil, a first gradient coil, and a second gradient coil, and wherein the sequence of commands includes commands to operate at least the RF coil, the first gradient coil, and the second gradient coil to produce the first pulse sequence.

9. The MRI system of claim 1 , wherein the determined times are determined at least in part by prioritizing the individual commands.

10. The MRI system of claim 1 , wherein the first controller is configured to issue the at least one command of the sequence of commands before completing reception of the sequence of commands from the at least one processor.

11. The MRI system of claim 1 , wherein the one or more components comprises an amplifier, and wherein the sequence of commands includes commands to operate one or more magnetics components through operation of the amplifier.

12. The MRI system of claim 1 , further comprising a power system configured to operate the MRI system using an average of less than 10 kilowatts during acquisition of the magnetic resonance data.

13. The MRI system of claim 1 , wherein the sequence of commands is a first sequence of commands, and wherein the first controller is further configured to:

receive, from the at least one processor, a second sequence of commands for controlling the one or more components to operate in accordance with a second pulse sequence; and

issue at least one command of the second sequence of commands to the one or more components before completing reception of the second sequence of commands from the at least one processor.

14. A method of performing magnetic resonance imaging (MRI) within an MRI system comprising one or more components configured to acquire magnetic resonance data, the method comprising:

receiving, by a first controller, from at least one processor configured to determine times to issue individual commands from the first controller to the one or more components, a sequence of commands for controlling the one or more components of the MRI system; and

issuing, by the first controller, at least one command of the sequence of commands to the one or more components in accordance with determined times to issue the at least one command.

15. The method of claim 14 , wherein the one or more components comprises at least one permanent magnet configured to produce a B 0 field that is less than or equal to 0.1 T and greater than or equal to 50 mT.

16. The method of claim 14 , further comprising:

receiving data from the one or more components by a second controller coupled to the first controller; and

providing the data received from the one or more components from the second controller to the at least one processor.

17. The method of claim 14 , wherein the one or more components comprises an RF coil, a first gradient coil and a second gradient coil, and wherein the sequence of commands includes commands to operate at least the RF coil, the first gradient coil and the second gradient coil to produce a first pulse sequence.

18. The method of claim 14 , wherein the one or more components comprises an amplifier, and wherein the sequence of commands includes commands to operate one or more magnetics components through operation of the amplifier.

19. The method of claim 14 , wherein the sequence of commands is a first sequence of commands, and wherein the method further comprises:

receiving, by the first controller from the at least one processor, a second sequence of commands for controlling the one or more components of the MRI system to operate in accordance with a second pulse sequence; and

issuing, by the first controller, at least one command of the second sequence of commands to the one or more components of the MRI system before completing reception of the second sequence of commands from the at least one processor.

20. At least one non-transitory computer readable storage medium storing instructions that, when executed by circuitry part of an MRI system comprising one or more components configured to acquire magnetic resonance data when operated, cause the MRI system to perform a method of performing magnetic resonance imaging, the method comprising:

receiving, by a first controller from at least one processor configured to determine times to issue individual commands from the first controller to the one or more components, a sequence of commands for controlling the one or more components of the MRI system to operate in accordance with a first pulse sequence; and

issuing, by the first controller, at least one command of the sequence of commands to the one or more components of the MRI system in accordance with the determined times to issue the at least one command.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 5, 2023
From: SACOLICK, LAURA; LOWTHERT, JONATHAN; JORDAN, JEREMY CHRISTOPHER; DYVORNE, HADRIEN A.
To: HYPERFINE RESEARCH, INC.
Reel/Frame 064156/0129 →
CHANGE OF NAME Recorded Jul 5, 2023
From: HYPERFINE RESEARCH, INC.
To: HYPERFINE, INC.
Reel/Frame 064206/0839 →
CHANGE OF NAME Recorded Jul 5, 2023
From: HYPERFINE, INC.
To: HYPERFINE OPERATIONS, INC.
Reel/Frame 064206/0857 →
Continuity (3)
Continuation 16830633 · Mar 26, 2020
Provisional Application 62839177 · Apr 26, 2019
Related Publication 20230349994A1 · Nov 2, 2023
References Cited (45)
US 5144242A · Zeilenga et al. · 1992 [cited by applicant]
US 5349296A · Cikotte et al. · 1994 [cited by applicant]
US 6160397A · Washburn et al. · 2000 [cited by applicant]
US 9541616B2 · Rothberg et al. · 2017 [cited by applicant]
US 9547057B2 · Rearick et al. · 2017 [cited by applicant]
US 9625544B2 · Poole et al. · 2017 [cited by applicant]
US 9645210B2 · Mcnulty et al. · 2017 [cited by applicant]
US 9817093B2 · Rothberg et al. · 2017 [cited by applicant]
US 10145913B2 · Hugon et al. · 2018 [cited by applicant]
US 10145922B2 · Rothberg et al. · 2018 [cited by applicant]
US 10222434B2 · Poole et al. · 2019 [cited by applicant]
US 10274561B2 · Poole et al. · 2019 [cited by applicant]
US 10281540B2 · Mileski et al. · 2019 [cited by applicant]
US 10281541B2 · Poole et al. · 2019 [cited by applicant]
US 10310037B2 · Mcnulty et al. · 2019 [cited by applicant]
US 10416264B2 · Sofka et al. · 2019 [cited by applicant]
US 10551452B2 · Rearick et al. · 2020 [cited by applicant]
US 10591561B2 · Sacolick et al. · 2020 [cited by applicant]
US 10709387B2 · Poole et al. · 2020 [cited by applicant]
US 20140278195A1 · Feiweier et al. · 2014 [cited by applicant]
US 20140285196A1 · Liu et al. · 2014 [cited by applicant]
US 20150153431A1 · Hancu et al. · 2015 [cited by applicant]
US 20150301143A1 · Banerjee et al. · 2015 [cited by applicant]
US 20150346305A1 · King · 2015 [cited by applicant]
US 20160128592A1 · Rosen et al. · 2016 [cited by applicant]
US 20160131727A1 · Sacolick et al. · 2016 [cited by applicant]
US 20160231407A1 · Biber et al. · 2016 [cited by applicant]
US 20170276749A1 · Hugon et al. · 2017 [cited by applicant]
US 20180143274A1 · Poole et al. · 2018 [cited by applicant]
US 20180143280A1 · Dyvorne et al. · 2018 [cited by applicant]
US 20190038233A1 · Poole et al. · 2019 [cited by applicant]
US 20190324098A1 · Mcnulty et al. · 2019 [cited by applicant]
US 20190353723A1 · Dyvorne et al. · 2019 [cited by applicant]
US 20190353726A1 · Poole et al. · 2019 [cited by applicant]
US 20200022611A1 · Nelson et al. · 2020 [cited by applicant]
US 20200022612A1 · Mcnulty et al. · 2020 [cited by applicant]
US 20200034998A1 · Schlemper et al. · 2020 [cited by applicant]
US 20200041588A1 · O'Halloran et al. · 2020 [cited by applicant]
US 20200045112A1 · Sacolick et al. · 2020 [cited by applicant]
US 20200058106A1 · Lazarus et al. · 2020 [cited by applicant]
US 20200150202A1 · Hugon et al. · 2020 [cited by applicant]
US 20200200844A1 · Boskamp et al. · 2020 [cited by applicant]
US 20200209334A1 · O'Halloran et al. · 2020 [cited by applicant]
First Office Action and Search Report for CN App. No. 202080045579.7 dated Dec. 29, 2023 (with machine English translation, 12 pages). [cited by applicant]
International Search Report and Written Opinion for International Application No. PCT/US2020/024860 mailed Jul. 27, 2020 (00354.70034WO00). [cited by applicant]