PROCESS FOR PREPARING FRAMBIONE
The present invention relates to a process for preparing frambione, comprising a step of condensing phenol and glyoxylic acid.
1 . A process for preparing frambione, comprising a step (a) of condensing phenol and glyoxylic acid to form a compound of formula (I) according to the following scheme:
2 . The process for preparing frambione as claimed in claim 1 , also comprising a step (b) in which compound (I) obtained on conclusion of step (a) is oxidized to form compound (IV).
3 . The process for preparing frambione as claimed in claim 2 , comprising a step (c) of condensing the compound of formula (IV), obtained on conclusion of step (b), with acetone to form a compound of formula (VII).
4 . The process for preparing frambione as claimed in claim 3 , comprising a step (d) of hydrogenation of the compound of formula (VII) obtained on conclusion of step (c).
5 . The process for preparing frambione as claimed in claim 1 , in which at least one compound chosen from phenol and glyoxylic acid is of biobased origin, and optionally acetone.
6 . The process for preparing frambione, comprising a step of condensing 4-hydroxybenzyl alcohol with acetone.
7 . A frambione characterized in that the average 13 C isotopic deviation is between −27‰ and −15‰.
8 . The frambione as claimed in claim 7 , characterized in that the biobased carbon content is greater than or equal to 50%.
9 . The frambione as claimed in claim 7 , characterized in that the biobased carbon content is less than or equal to 110%.
10 . The frambione as claimed in claim 7 , characterized in that the ratio (D/H) 5 /(D/H) 4 is less than or equal to 1.10.
11 . The frambione as claimed in of claim 7 , characterized in that the ratio (D/H) 3 /(D/H) 2 is less than or equal to 1.10.
12 . The frambione as claimed in claim 7 , characterized in that 10 carbon atoms are of biobased origin.
13 . (canceled)
14 . A composition comprising the frambione as claimed in claim 7 .
15 . The composition of claim 14 chosen from the group consisting of food products, beverages, cosmetic formulations, pharmaceutical formulations, and fragrances.
16 . A composition comprising the frambione obtained as claimed in the process of claim 1 .
17 . The composition of claim 16 chosen from the group consisting of food products, beverages, cosmetic formulations, pharmaceutical formulations, and fragrances.
18 . The frambione as claimed in claim 7 characterized in that the ratio (D/H) 5 /(D/H) 4 is less than or equal to 0.85.
19 . The frambione as claimed in claim 7 characterized in that the ratio (D/H) 3 /(D/H) 2 is less than or equal to 0.80.
20 . A flavoring or fragrance consisting of the frambione as claimed in claim 1 .