Patent Application
Utility
PCT National Stage
App. No. 18/259,884
· Confirmation No. 7199
CYCLIC-DISULFIDE MODIFIED PHOSPHATE BASED OLIGONUCLEOTIDE PRODRUGS
Inventors:
Alexander V. KEL’IN, Justin M. PIERSON, Jayaprakash K. NAIR, Martin A. MAIER, Anna BISBE, Cheng TANG
Applicant:
ALNYLAM PHARMACEUTICALS, INC.
Non Final Action Mailed
View Publication ↗
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Code | Description | Pages | ||
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| 2026-08-20 | CTRS |
Requirement for Restriction/Election | 8 | View | |
| 2026-05-29 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2026-05-29 | M903 |
Notice of Designated Office (DO) / Elected Office (EO) Acceptance Mailed | 2 | View | |
| 2026-05-29 | WCLM |
Claims Worksheet (PTO-2022) | 1 | View | |
| 2026-05-29 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2026-03-18 | PEFRSEQ |
Response to Pre-Exam Sequence Notice | — | View | |
| 2026-03-18 | SPEC |
Specification | 185 | View | |
| 2026-03-18 | SPEC |
Specification | 185 | View | |
| 2026-03-18 | PEFRSEQ |
Response to Pre-Exam Sequence Notice | 1 | View | |
| 2026-03-18 | SPEC |
Specification | 1 | View | |
| 2026-03-18 | REM |
Applicant Arguments/Remarks Made in an Amendment | 2 | View | |
| 2026-03-18 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2026-01-30 | SREXR.G |
Acceptance of Permission to Access Search Results | 1 | View | |
| 2026-01-30 | PD.AUTH.G |
Acceptance of Permission to Access Application | 1 | View | |
| 2026-01-30 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2026-01-30 | WCLM |
Claims Worksheet (PTO-2022) | 1 | View | |
| 2026-01-30 | 371.RQ.M922 |
371 (National Stage) Requirements for Sequence Disclosure Notice Form M922 | 2 | View | |
| 2026-01-30 | PEFN |
Pre-Exam Formalities Notice | 1 | View | |
| 2026-01-09 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 5 | View | |
| 2026-01-09 | FOR |
Foreign Reference | 86 | View | |
| 2026-01-09 | FOR |
Foreign Reference | 158 | View | |
| 2026-01-09 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2026-01-05 | SEQREQ |
Sequence Problem Attachment from Examiner | 2 | View | |
| 2025-04-16 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2025-04-14 | CFILE |
Request for Corrected Filing Receipt | 1 | View | |
| 2025-04-14 | ADS |
Application Data Sheet | 10 | View | |
| 2025-04-14 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2024-10-17 | NTC.PUB |
Notice of Publication | 1 | View | |
| 2024-06-20 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2024-06-20 | M903 |
Notice of Designated Office (DO) / Elected Office (EO) Acceptance Mailed | 2 | View | |
| 2024-06-20 | WCLM |
Claims Worksheet (PTO-2022) | 1 | View | |
| 2024-06-20 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2024-06-20 | WELCOME.LET |
Welcome Letter from USPTO Director and Deputy Director | 1 | View | |
| 2023-10-31 | N417 |
Electronic Filing System Acknowledgment Receipt | 4 | View | |
| 2023-10-31 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 5 | View | |
| 2023-09-08 | CRFE |
Sequence Listing in Computer Readable Format, No errors found | — | View | |
| 2023-09-08 | A.PE |
Preliminary Amendment | 1 | View | |
| 2023-09-08 | SPEC |
Specification | 1 | View | |
| 2023-09-08 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2023-09-08 | CRFS |
CRF Statement that Sequence Listing text file (CRF) and paper/pdf Sequence Listing are the same | 1 | View | |
| 2023-09-08 | SEQLIST |
Sequence Listing | 55 | View | |
| 2023-09-08 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2023-09-08 | SEQ.TXT |
Sequence Listing (Text File) | 1 | View | |
| 2023-09-08 | CRFE |
Sequence Listing in Computer Readable Format, No errors found | 27 | View | |
| 2023-08-10 | OATH |
Oath or Declaration filed | 6 | View | |
| 2023-08-10 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2023-07-03 | CRFD |
Sequence Listing in Computer Readable Format is Defective | — | View | |
| 2023-07-03 | CRFD |
Sequence Listing in Computer Readable Format is Defective | 19 | View | |
| 2023-06-29 | A.PE |
Preliminary Amendment | — | View | |
| 2023-06-29 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 4 | View | |
| 2023-06-29 | A.PE |
Preliminary Amendment | 1 | View | |
| 2023-06-29 | SPEC |
Specification | 13 | View | |
| 2023-06-29 | CLM |
Claims | 11 | View | |
| 2023-06-29 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2023-06-29 | 371P |
Documents submitted with 371 (National Stage) Applications | 7 | View | |
| 2023-06-29 | ADS |
Application Data Sheet | 10 | View | |
| 2023-06-29 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2023-06-29 | TRNA |
Transmittal of New Application | 4 | View | |
| 2023-06-29 | N417 |
Electronic Filing System Acknowledgment Receipt | 4 | View | |
| 2023-06-29 | 371P |
Documents submitted with 371 (National Stage) Applications | 6 | View | |
| 2023-06-29 | FOR |
Foreign Reference | 90 | View | |
| 2023-06-29 | FOR |
Foreign Reference | 172 | View | |
| 2023-06-29 | FOR |
Foreign Reference | 102 | View | |
| 2023-06-29 | FOR |
Foreign Reference | 122 | View | |
| 2023-06-29 | 371P |
Documents submitted with 371 (National Stage) Applications | 206 | View | |
| 2023-06-29 | FOR |
Foreign Reference | 135 | View | |
| 2023-06-29 | PA.. |
Power of Attorney | 2 | View | |
| 2023-06-29 | DRW |
Drawings-only black and white line drawings | 18 | View | |
| 2023-06-29 | SEQ.XML |
Sequence Listing (XML File) | 1 | View | |
| 2023-06-29 | FRPR |
Certified Copy of Foreign Priority Application | 180 | View | |
| 2023-06-29 | P.N.101.CONV |
PCT/RO/101 - Request form for new International Application - Conventional | 5 | View | |
| 2023-06-29 | FRPR |
Certified Copy of Foreign Priority Application | 176 | View | |
| 2023-06-29 | ABST |
Abstract | 2 | View | |
| 2023-06-29 | CLM |
Claims | 17 | View | |
| 2023-06-29 | DRW |
Drawings-only black and white line drawings | 10 | View | |
| 2023-06-29 | ABST |
Abstract | 2 | View | |
| 2023-06-29 | SPEC |
Specification | 177 | View |
Inventors
Alexander V. KEL’IN
Cambridge, MA
Justin M. PIERSON
Cambridge, MA
Jayaprakash K. NAIR
Cambridge, MA
Martin A. MAIER
Cambridge, MA
Anna BISBE
Cambridge, MA
Cheng TANG
Cambridge, MA
Attorneys & Agents of Record
Classification
USPC
549/20
C07F9/655345
C07F9/655363
C07F9/655381
C07F9/65586
C07F9/6561
C07H21/02
Prosecution
- Examiner
- ONDACHI, PAULINE WANJIKU MUCH
- Art Unit
- 1627
- Customer No.
- 84717
- Docket No.
- 29520.1505-US/585054
- Confirmation No.
- 7199
Publication
- Pub. No.
- US20240343746A1
- Pub. Date
- 2024-10-17
Parent
PCT
is a National Stage Entry of
→
PCT/US2021/065636
Filed 2021-12-30
· Non Final Action Mailed
Parent
Claims priority from a provisional application
→
App. 63/287,833
Filed 2021-12-09
· Provisional Application Expired
Parent
Claims priority from a provisional application
→
App. 63/132,535
Filed 2020-12-31
· Provisional Application Expired
SECURITY INTEREST
Recorded 2025-10-01
from
BISBE, ANNA,
NAIR, JAYAPRAKASH K.,
TANG, CHENG,
PIERSON, JUSTIN M.,
KEL'IN, ALEXANDER V.,
MAIER, MARTIN A.
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded 2023-08-10
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Quick Facts
- App. No.
- 18/259,884
- Filed
- 2023-06-29
- Pub. No.
- US20240343746A1
- Examiner
- ONDACHI, PAULINE WANJIKU MUCH
- Art Unit
- 1627
External Links