Patent Application
Utility
PCT National Stage
App. No. 18/262,302
· Confirmation No. 8225
MODIFIED DOUBLE STRANDED OLIGONUCLEOTIDES
Inventors:
Mark K. SCHLEGEL, Adam CASTORENO, Christopher BROWN, Lucas D. BONDURANT, Anna BORODOVSKY, William CANTLEY, Elena CASTELLANOS-RIZALDOS, Aimee M. DEATON, Jonathan Edward FARLEY, Elane FISHILEVICH, John Michael GANSNER, Jason GILBERT, Vasant R. JADHAV, Charalambos KAITTANIS, Mark KEATING, Jingxuan LIU, James D. MCININCH, Stuart MILSTEIN, Bhaumik A. PANDYA, Mangala Meenakshi SOUNDARAPANDIAN, Jeffrey ZUBER
Applicant:
ALNYLAM PHARMACEUTICALS, INC.
Notice of Allowance Mailed -- Application Received in Office of Publications
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| 2026-07-13 | M327 |
Miscellaneous Communication to Applicant - No Action Count | 3 | View | |
| 2026-06-12 | NOA |
Notice of Allowance and Fees Due (PTOL-85) | 12 | View | |
| 2026-06-12 | EXIN |
Examiner Interview Summary Record (PTOL - 413) | 1 | View | |
| 2026-06-12 | 892 |
List of references cited by examiner | 1 | View | |
| 2026-06-12 | SRFW |
Search information including classification, databases and other search related notes | 2 | View | |
| 2026-06-12 | IIFW |
Issue Information including classification, examiner, name, claim, renumbering, etc. | 3 | View | |
| 2026-06-12 | 1449 |
List of References cited by applicant and considered by examiner | 5 | View | |
| 2026-06-12 | SRNT |
Examiner's search strategy and results | 8 | View | |
| 2026-06-12 | SRNT |
Examiner's search strategy and results | 5 | View | |
| 2026-06-12 | SRNT |
Examiner's search strategy and results | 162 | View | |
| 2026-06-12 | 1449 |
List of References cited by applicant and considered by examiner | 4 | View | |
| 2026-06-12 | BIB |
Bibliographic Data Sheet | 2 | View | |
| 2026-06-12 | 1449 |
List of References cited by applicant and considered by examiner | 5 | View | |
| 2026-03-25 | ELC. |
Response to Election / Restriction Filed | — | View | |
| 2026-03-25 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2026-03-25 | ELC. |
Response to Election / Restriction Filed | 1 | View | |
| 2026-03-25 | REM |
Applicant Arguments/Remarks Made in an Amendment | 3 | View | |
| 2026-03-25 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2026-01-27 | CTRS |
Requirement for Restriction/Election | 7 | View | |
| 2026-01-27 | 892 |
List of references cited by examiner | 1 | View | |
| 2026-01-05 | FOR |
Foreign Reference | 147 | View | |
| 2026-01-05 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 5 | View | |
| 2026-01-05 | FOR |
Foreign Reference | 260 | View | |
| 2026-01-05 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2026-01-05 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2025-12-08 | FOR |
Foreign Reference | 147 | View | |
| 2025-12-08 | FOR |
Foreign Reference | 11 | View | |
| 2025-12-08 | FOR |
Foreign Reference | 38 | View | |
| 2025-12-08 | FOR |
Foreign Reference | 31 | View | |
| 2025-12-08 | FOR |
Foreign Reference | 23 | View | |
| 2025-12-08 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 5 | View | |
| 2025-12-08 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2025-12-08 | FOR |
Foreign Reference | 140 | View | |
| 2025-12-08 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2025-09-17 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2025-09-12 | CFILE |
Request for Corrected Filing Receipt | 2 | View | |
| 2025-09-12 | ADS |
Application Data Sheet | 16 | View | |
| 2025-09-12 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2025-09-12 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2025-09-12 | OATH |
Oath or Declaration filed | 1 | View | |
| 2025-09-11 | NTC.PUB |
Notice of Publication | 1 | View | |
| 2025-06-04 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2025-06-04 | M903 |
Notice of Designated Office (DO) / Elected Office (EO) Acceptance Mailed | 2 | View | |
| 2025-06-04 | WCLM |
Claims Worksheet (PTO-2022) | 1 | View | |
| 2025-06-04 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2025-06-02 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2023-12-08 | SA.. |
Supplemental Response or Supplemental Amendment | — | View | |
| 2023-12-08 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2023-12-08 | PEFR |
Applicant Response to Pre-Exam Formalities Notice | 2 | View | |
| 2023-12-08 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2023-12-08 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2023-12-08 | PEFR |
Applicant Response to Pre-Exam Formalities Notice | 1 | View | |
| 2023-12-08 | CLM |
Claims | 6 | View | |
| 2023-12-08 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2023-11-30 | PD.AUTH.G |
Acceptance of Permission to Access Application | 1 | View | |
| 2023-11-30 | SREXR.G |
Acceptance of Permission to Access Search Results | 1 | View | |
| 2023-11-30 | M905 |
Notice of DO/EO Missing Requirements Mailed | 2 | View | |
| 2023-11-30 | WCLM |
Claims Worksheet (PTO-2022) | 1 | View | |
| 2023-11-30 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2023-11-30 | WELCOME.LET |
Welcome Letter from USPTO Director and Deputy Director | 1 | View | |
| 2023-11-02 | PA.. |
Power of Attorney | 1 | View | |
| 2023-11-02 | OATH |
Oath or Declaration filed | 21 | View | |
| 2023-11-02 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2023-11-02 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2023-07-20 | CRFE |
Sequence Listing in Computer Readable Format, No errors found | — | View | |
| 2023-07-20 | A.PE |
Preliminary Amendment | — | View | |
| 2023-07-20 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 4 | View | |
| 2023-07-20 | 371P |
Documents submitted with 371 (National Stage) Applications | 6 | View | |
| 2023-07-20 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2023-07-20 | A.PE |
Preliminary Amendment | 1 | View | |
| 2023-07-20 | SPEC |
Specification | 1 | View | |
| 2023-07-20 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2023-07-20 | CRFS |
CRF Statement that Sequence Listing text file (CRF) and paper/pdf Sequence Listing are the same | 1 | View | |
| 2023-07-20 | FOR |
Foreign Reference | 260 | View | |
| 2023-07-20 | TRNA |
Transmittal of New Application | 4 | View | |
| 2023-07-20 | ADS |
Application Data Sheet | 16 | View | |
| 2023-07-20 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2023-07-20 | N417 |
Electronic Filing System Acknowledgment Receipt | 4 | View | |
| 2023-07-20 | SPEC |
Specification | 179 | View | |
| 2023-07-20 | SPEC |
Specification | 179 | View | |
| 2023-07-20 | SEQ.TXT |
Sequence Listing (Text File) | 1 | View | |
| 2023-07-20 | CRFE |
Sequence Listing in Computer Readable Format, No errors found | 27 | View | |
| 2023-07-20 | 371P |
Documents submitted with 371 (National Stage) Applications | 1 | View | |
| 2023-07-20 | 371P |
Documents submitted with 371 (National Stage) Applications | 1 | View | |
| 2023-07-20 | FRPR |
Certified Copy of Foreign Priority Application | 203 | View | |
| 2023-07-20 | FRPR |
Certified Copy of Foreign Priority Application | 170 | View | |
| 2023-07-20 | FRPR |
Certified Copy of Foreign Priority Application | 109 | View | |
| 2023-07-20 | FRPR |
Certified Copy of Foreign Priority Application | 427 | View | |
| 2023-07-20 | FRPR |
Certified Copy of Foreign Priority Application | 302 | View | |
| 2023-07-20 | FRPR |
Certified Copy of Foreign Priority Application | 180 | View | |
| 2023-07-20 | FRPR |
Certified Copy of Foreign Priority Application | 452 | View | |
| 2023-07-20 | FRPR |
Certified Copy of Foreign Priority Application | 262 | View | |
| 2023-07-20 | P.N.101.CONV |
PCT/RO/101 - Request form for new International Application - Conventional | 13 | View | |
| 2023-07-20 | FRPR |
Certified Copy of Foreign Priority Application | 234 | View | |
| 2023-07-20 | ABST |
Abstract | 2 | View | |
| 2023-07-20 | P.N.101.CONV |
PCT/RO/101 - Request form for new International Application - Conventional | 15 | View | |
| 2023-07-20 | CLM |
Claims | 6 | View | |
| 2023-07-20 | DRW |
Drawings-only black and white line drawings | 17 | View | |
| 2023-07-20 | SPEC |
Specification | 156 | View |
Inventors
Mark K. SCHLEGEL
Cambridge, MA
Adam CASTORENO
Cambridge, MA
Christopher BROWN
Cambridge, MA
Lucas D. BONDURANT
Cambridge, MA
Anna BORODOVSKY
Cambridge, MA
William CANTLEY
Cambridge, MA
Elena CASTELLANOS-RIZALDOS
Cambridge, MA
Aimee M. DEATON
Cambridge, MA
Jonathan Edward FARLEY
Cambridge, MA
Elane FISHILEVICH
Cambridge, MA
John Michael GANSNER
Cambridge, MA
Jason GILBERT
Cambridge, MA
Vasant R. JADHAV
Cambridge, MA
Charalambos KAITTANIS
Cambridge, MA
Mark KEATING
Cambridge, MA
Jingxuan LIU
Cambridge, MA
James D. MCININCH
Cambridge, MA
Stuart MILSTEIN
Cambridge, MA
Bhaumik A. PANDYA
Cambridge, MA
Mangala Meenakshi SOUNDARAPANDIAN
Cambridge, MA
Jeffrey ZUBER
Cambridge, MA
Attorneys & Agents of Record
Classification
USPC
536/24.5
C12N15/113
C12N2310/11
C12N2310/312
C12N2310/315
C12N2310/321
C12N2310/322
C12N2310/3515
C12N2310/3521
C12N2310/3533
Prosecution
- Examiner
- SU-TOBON, QIWEN NMN
- Art Unit
- 1636
- Customer No.
- 90162
- Docket No.
- 051058-099300USPX
- Confirmation No.
- 8225
Publication
- Pub. No.
- US20250283071A1
- Pub. Date
- 2025-09-11
Parent
PCT
is a National Stage Entry of
→
PCT/US2021/057016
Filed 2021-10-28
· Notice of Allowance Mailed -- Application Received in Office of Publications
Parent
Claims priority from a provisional application
→
App. 63/140,714
Filed 2021-01-22
· Provisional Application Expired
Parent
Claims priority from a provisional application
→
App. 63/146,115
Filed 2021-02-05
· Provisional Application Expired
Parent
Claims priority from a provisional application
→
App. 63/148,991
Filed 2021-02-12
· Provisional Application Expired
Parent
Claims priority from a provisional application
→
App. 63/153,983
Filed 2021-02-26
· Provisional Application Expired
Parent
Claims priority from a provisional application
→
App. 63/156,476
Filed 2021-03-04
· Provisional Application Expired
Parent
Claims priority from a provisional application
→
App. 63/161,313
Filed 2021-03-15
· Provisional Application Expired
Parent
Claims priority from a provisional application
→
App. 63/164,467
Filed 2021-03-22
· Provisional Application Expired
Parent
Claims priority from a provisional application
→
App. 63/179,607
Filed 2021-04-26
· Provisional Application Expired
Parent
Claims priority from a provisional application
→
App. 63/181,748
Filed 2021-04-29
· Provisional Application Expired
SECURITY INTEREST
Recorded 2025-10-01
from
KAITTANIS, CHARALAMBOS,
KEATING, MARK,
LIU, JINGXUAN,
BROWN, CHRISTOPHER,
CASTELLANOS-RIZALDOS, ELENA,
DEATON, AIMEE M.,
FARLEY, JONATHAN EDWARD,
FISHILEVICH, ELANE,
MILSTEIN, STUART,
PANDYA, BHAUMIK A.,
BONDURANT, LUCAS D.,
CASTORENO, ADAM,
GANSNER, JOHN MICHAEL,
MCININCH, JAMES D.,
SCHLEGEL, MARK K.,
SOUNDARAPANDIAN, MANGALA MEENAKSHI,
ZUBER, JEFFREY,
BORODOVSKY, ANNA,
CANTLEY, WILLIAM,
JADHAV, VASANT R.,
GILBERT, JASON
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded 2025-06-11
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Quick Facts
- App. No.
- 18/262,302
- Filed
- 2023-07-20
- Pub. No.
- US20250283071A1
- Examiner
- SU-TOBON, QIWEN NMN
- Art Unit
- 1636
External Links