Package irradiation dose sensor
A radiation dose sensor that measures a radiation dose of a biocontainer formed for a first material includes a first electrode, a second electrode, and a film. The first electrode has a plurality of first fingers. And the second electrode has a plurality of second fingers. The fingers of the first electrode extend towards and are interdigitated with the fingers of the second electrode that extend towards the first electrode with gaps formed between the first and second fingers. The film coats the interdigitated fingers and is disposed within the gaps. The film is formed of a second material that is similar to the first material that forms the biocontainer.
1. A radiation dose sensor for measuring a radiation dose of a biocontainer formed of a first material, the radiation dose sensor comprising:
a first electrode having a plurality of first fingers;
a second electrode having a plurality of second fingers, the plurality of first fingers extending from the first electrode towards the second electrode, the plurality of second fingers extending from the second electrode towards the first electrode such that the first fingers are interdigitated with the second fingers with gaps defined between the first fingers and the second fingers; and
a film coating the plurality of first fingers and the plurality of second fingers such that the film is disposed within the gaps, the film formed of a second material similar to the first material forming the biocontainer, the film configured to degrade when exposed to radiation to determine a radiation dose of the sensor.
2. The radiation dose sensor according to claim 1 , further comprising a backing material configured to secure the first electrode relative to the second electrode.
3. The radiation dose sensor according to claim 1 , wherein the radiation dose sensor is configured to provide measurements of an electrical property through the film.
4. The radiation dose sensor according to claim 3 , wherein the second material includes nanoparticles configured to enhance a sensitivity of the electrical property of the radiation dose sensor.
5. The radiation dose sensor according to claim 1 , wherein the radiation dose sensor is configured to measure a capacitance between the first electrode and the second electrode.
6. The radiation dose sensor according to claim 1 , wherein the radiation dose sensor is configured to measure a resistance through the film.
7. The radiation dose sensor according to claim 1 , further comprising support electronics configured to store measurements, transmit measurements, or take measurements with the radiation dose sensor.
8. The radiation dose sensor according to claim 1 , wherein the film forms a portion of the biocontainer.
9. The radiation dose sensor according to claim 1 , wherein the second material is selected from the group consisting of ethylene-vinyl acetate (EVA), ethylene vinyl alcohol (EVOH), low-density polyethylene (LDPE), linear low-density polyethylene (LLDPE), nylon plastic (PA), polyethylene terephthalate (PET), fluoropolymers, polyvinyl chloride (PVC), thermoplastic polyurethane (TPU), platinum cured silicone Si (pt), liquid silicone rubber Si (LSR), fluoropolymers, thermoplastic elastomers (TPE), high-density polyethylene (HDPE), polypropylene (PP), polycarbonate (PC), polysulfone (PSU), polyphenylsulfone (PPSU), polybutylene terephthalate (PBT), polyetheretherketone (PEEK), polyoxymethylene (POM), acrylonitrile butadiene styrene (ABS), silicone (Si), ethylene propylene diene terpolymer (EPDM), thermoplastic vulcanizates (TPV), acrylate, and cynate.
10. The radiation dose sensor according to claim 1 , wherein the radiation dose sensor is configured to provide measurements between cycles of delivery of radiation.
11. A method of manufacturing a radiation dose sensor, the method comprising:
interdigitating fingers of a first electrode with fingers of a second electrode; and
coating the interdigitated fingers with a material to form a film over the interdigitated fingers such that the film is disposed within gaps defined between the fingers of the first electrode and the fingers of the second electrode, the material of the film being selected to be similar to a material forming a biocontainer associated with the radiation dose sensor, the film configured to degrade when exposed to radiation to measure a dose of radiation.
12. The method according to claim 11 , wherein coating the interdigitated fingers includes forming a wall of a biocontainer with the interdigitated fingers embedded within the wall of the biocontainer.
13. The method according to claim 11 , further comprising disposing nanoparticles within the gaps defined between the fingers of the first electrode and the fingers of the second electrode.
14. A method of predicting a change impact of a biocontainer due to irradiation thereof, the method comprising:
associating a radiation dose sensor with a biocontainer, the radiation dose sensor including a film formed of a material similar to a material forming the associated biocontainer;
irradiating the radiation dose sensor and the biocontainer such that the film degrades; and
predicting the change impact of irradiation on the biocontainer based on the irradiation of the radiation dose sensor.
15. The method according to claim 14 , further comprising:
storing products in the biocontainer after irradiation of the biocontainer; and
correlating a change impact to the change impact of the irradiation on the biocontainer to the products stored within the biocontainer.
16. The method according to claim 14 , further comprising measuring a change in properties of the radiation dose sensor over time after irradiation of the radiation dose sensor.
17. The method according to claim 16 , further comprising:
storing products within the biocontainer; and
correlating the change in properties of the radiation dose sensor over time to products stored in the biocontainer.
18. A kit comprising:
a package;
a first sterilized biocontainer disposed in the package, the first sterilized biocontainer formed of a first material; and
a first sensor disposed in the package, the first sensor comprising:
a first electrode having a plurality of first fingers;
a second electrode having a plurality of second fingers, the plurality of first fingers extending from the first electrode towards the second electrode, the plurality of second fingers extending from the second electrode towards the first electrode such that the first fingers are interdigitated with the second fingers with gaps defined between the first and second fingers; and
a film coating the plurality of first fingers and the plurality of second fingers such that the film is disposed within the gaps, the film formed of the first material forming the first sterilized biocontainer, the film configured to degrade when exposed to radiation to determine a radiation dose of the sensor.
19. The kit according to claim 18 , further comprising a second sterilized biocontainer disposed within the package, the second sterilized biocontainer formed of the first material.
20. The kit according to claim 18 , wherein the first sterilized biocontainer is selected from the group consisting of a film, a bag, a tube, a conduit, a connector, an O-ring, or an adhesive.