COSMETIC COMPOSITIONS AND METHODS OF USE THEREOF
The disclosure provides cosmetic compositions including cannabigerol (CBG), as well as methods of using the same for reducing skin redness, improving skin barrier functionality, brightening the skin of a subject, and enhancing the outward appearance of the skin of a subject (e.g., a male or female human subject).
1 . A cosmetic composition comprising cannabigerol (CBG).
2 . A cosmetic composition comprising CBG and capric/caprylic triglyceride (CCT).
3 . The cosmetic composition of claim 1 or 2 , wherein the composition further comprises squalane.
4 . A cosmetic composition comprising CBG and squalane.
5 . The cosmetic composition of any one of claims 1 - 4 , wherein the concentration of CBG in the cosmetic composition is from about 0.1% w/w to about 10% w/w.
6 . The cosmetic composition of claim 5 , wherein the concentration of CBG in the cosmetic composition is from about 0.5% w/w to about 5% w/w CBG.
7 . The cosmetic composition of claim 6 , wherein the concentration of CBG in the cosmetic composition is about 1% w/w.
8 . The cosmetic composition of claim 6 , wherein the concentration of CBG in the cosmetic composition is about 2% w/w.
9 . The cosmetic composition of claim 6 , wherein the concentration of CBG in the cosmetic composition is about 4% w/w.
10 . The cosmetic composition of any one of claims 1 - 9 , wherein the composition further comprises CCT.
11 . The cosmetic composition of any one of claims 1 - 10 , wherein the composition further comprises an additional cannabinoid.
12 . The cosmetic composition of claim 11 , wherein the additional cannabinoid is cannabidiol (CBD).
13 . The cosmetic composition of any one of claims 1 - 12 , wherein the composition further comprises one or more essential oils.
14 . The cosmetic composition of claim 13 , wherein the one or more essential oils comprise Lavandula angustifolia oil.
15 . The cosmetic composition of claim 13 or 14 , wherein the one or more essential oils comprise hemp oil.
16 . The cosmetic composition of claim 15 , wherein the hemp oil is Cannabis sativa seed oil.
17 . The cosmetic composition of claim 13 , wherein the one or more essential oils comprise Lavandula angustifolia oil and Cannabis sativa seed oil.
18 . The cosmetic composition of any one of claims 1 - 17 , wherein the composition further comprises one or more plant extracts.
19 . The cosmetic composition of claim 18 , wherein the plant extract is a flower, leaf, or stem extract.
20 . The cosmetic composition of claim 19 , wherein the plant extract is a Cannabis sativa flower, leaf, or stem extract.
21 . The cosmetic composition of any one of claims 1 - 20 , wherein the composition is formulated for topical administration to the skin of a human subject.
22 . The cosmetic composition of claim 21 , wherein the composition is a patch, liquid, gel, lotion, paste, cream, foam, serum, ointment, or stick.
23 . A method of improving the outward appearance of the skin of a human subject, the method comprising administering to the subject the cosmetic composition of any one of claims 1 - 22 .
24 . A method of improving skin barrier function in a human subject, the method comprising administering to the subject the cosmetic composition of any one of claims 1 - 22 .
25 . A method of reducing transepidermal water loss in a human subject, the method comprising administering to the subject the cosmetic composition of any one of claims 1 - 22 .
26 . A method of reducing redness in the skin of a human subject, the method comprising administering to the subject the cosmetic composition of any one of claims 1 - 22 .
27 . A method of reducing flaking in the skin of a human subject, the method comprising administering to the subject the cosmetic composition of any one of claims 1 - 22 .
28 . A method of clearing acne in a human subject, the method comprising administering to the subject the cosmetic composition of any one of claims 1 - 22 .
29 . A method of reducing skin discoloration in a human subject having eczema, the method comprising administering to the subject the cosmetic composition of any one of claims 1 - 22 .
30 . A method of brightening the skin of a human subject, the method comprising administering to the subject the cosmetic composition of any one of claims 1 - 22 .
31 . A method of increasing skin luminosity in a human subject, the method comprising administering to the subject the cosmetic composition of any one of claims 1 - 22 .
32 . A method of reducing visual dullness in the skin of a human subject, the method comprising administering to the subject the cosmetic composition of any one of claims 1 - 22 .
33 . The method of any one of claims 23 - 32 , wherein the cosmetic composition increases skin hydration, smooths skin, renews skin, and/or cleanses skin.
34 . The method of any one of claims 23 - 33 , wherein the cosmetic composition is administered to the subject topically.
35 . The method of any one of claims 23 - 34 , wherein the cosmetic composition is administered to the subject one or more times daily, optionally wherein the cosmetic composition is administered to the subject once daily, twice daily, or three times daily.
36 . The method of claim 35 , wherein the cosmetic composition is administered to the subject once daily.
37 . The method of claim 35 , wherein the cosmetic composition is administered to the subject twice daily, optionally wherein the cosmetic composition is administered to the subject once in the morning and once in the evening.
38 . The method of claim 35 , wherein the cosmetic composition is administered to the subject three times daily.
39 . The method of any one of claims 35 - 38 , wherein the cosmetic composition is administered to the subject for at least 7 continuous days.
40 . The method of claim 39 , wherein the cosmetic composition is administered to the subject for at least 14 continuous days.
41 . The method of claim 40 , wherein the cosmetic composition is administered to the subject for at least 28 continuous days.
42 . A method of manufacturing the cosmetic composition of any one of claims 1 - 22 , the method comprising admixing CBG in one or more carriers, diluents, or excipients.
43 . The method of claim 42 , wherein the CBG is further admixed with CCT.
44 . The method of claim 42 or 43 , wherein the CBG is further admixed with squalane.
45 . The method of any one of claims 42 - 44 , wherein the CBG is further admixed with an additional cannabinoid.
46 . The method of claim 45 , wherein the additional cannabinoid is CBD.
47 . The method of any one of claims 42 - 46 , wherein the CBG is further admixed with one or more essential oils.
48 . The method of claim 47 , wherein the one or more essential oils comprise Lavandula angustifolia oil.
49 . The method of claim 47 or 48 , wherein the one or more essential oils comprise hemp oil.
50 . The method of claim 49 , wherein the hemp oil is Cannabis sativa seed oil.
51 . The method of claim 47 , wherein the one or more essential oils comprise Lavandula angustifolia oil and Cannabis sativa seed oil.
52 . The method of any one of claims 42 - 51 , wherein the CBG is further admixed with one or more plant extracts.
53 . The method of claim 52 , wherein the plant extract is a flower, leaf, or stem extract.
54 . The method of claim 53 , wherein the plant extract is a Cannabis sativa flower, leaf, or stem extract.
55 . The method of any one of claims 42 - 54 , wherein the composition is formulated such that the final concentration of CBG in the composition is from about 0.1% w/w to about 10% w/w.
56 . The method of claim 55 , wherein the composition is formulated such that the final concentration of CBG in the composition is from about 0.5% w/w to about 5% w/w.
57 . The method of claim 56 , wherein the composition is formulated such that the final concentration of CBG in the composition is about 1% w/w.
58 . The method of claim 56 , wherein the composition is formulated such that the final concentration of CBG in the composition is about 2% w/w.
59 . The method of claim 56 , wherein the composition is formulated such that the final concentration of CBG in the composition is about 4% w/w
60 . The method of any one of claims 42 - 59 , wherein the cosmetic composition is formulated for topical administration to the skin of a human subject.
61 . The method of claim 60 , wherein the composition is a patch, liquid, gel, lotion, paste, cream, foam, serum, ointment, or stick.