Patent Application
Utility
PCT National Stage
App. No. 18/272,448
· Confirmation No. 7507
MODIFIED OLIGONUCLEOTIDES
Applicant:
ALNYLAM PHARMACEUTICALS, INC.
Response to Non-Final Office Action Entered and Forwarded to Examiner
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Code | Description | Pages | ||
|---|---|---|---|---|---|
| 2026-07-15 | ELC. |
Response to Election / Restriction Filed | — | View | |
| 2026-07-15 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2026-07-15 | ELC. |
Response to Election / Restriction Filed | 1 | View | |
| 2026-07-15 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2026-07-15 | REM |
Applicant Arguments/Remarks Made in an Amendment | 2 | View | |
| 2026-07-15 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2026-07-15 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2026-05-21 | CTRS |
Requirement for Restriction/Election | 9 | View | |
| 2026-05-21 | 892 |
List of references cited by examiner | 1 | View | |
| 2026-05-06 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2026-05-06 | WCLM |
Claims Worksheet (PTO-2022) | 2 | View | |
| 2026-05-06 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2026-05-06 | M903 |
Notice of Designated Office (DO) / Elected Office (EO) Acceptance Mailed | 2 | View | |
| 2026-03-06 | A.PE |
Preliminary Amendment | — | View | |
| 2026-03-06 | SPEC |
Specification | 231 | View | |
| 2026-03-06 | SPEC |
Specification | 231 | View | |
| 2026-03-06 | A.PE |
Preliminary Amendment | 1 | View | |
| 2026-03-06 | SPEC |
Specification | 1 | View | |
| 2026-03-06 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2026-03-06 | SEQLIST |
Sequence Listing | 1 | View | |
| 2026-03-06 | LET. |
Miscellaneous Incoming Letter | 3 | View | |
| 2026-03-06 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2026-03-06 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2026-01-21 | PEFN |
Pre-Exam Formalities Notice | 1 | View | |
| 2026-01-21 | PEFN |
Pre-Exam Formalities Notice | 1 | View | |
| 2026-01-21 | 371.RQ.M922 |
371 (National Stage) Requirements for Sequence Disclosure Notice Form M922 | 3 | View | |
| 2026-01-21 | SREXR.G |
Acceptance of Permission to Access Search Results | 1 | View | |
| 2026-01-21 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2026-01-21 | PD.AUTH.G |
Acceptance of Permission to Access Application | 1 | View | |
| 2026-01-21 | WCLM |
Claims Worksheet (PTO-2022) | 2 | View | |
| 2026-01-15 | SEQREQ |
Sequence Problem Attachment from Examiner | 2 | View | |
| 2026-01-07 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2026-01-05 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2026-01-05 | CFILE |
Request for Corrected Filing Receipt | 2 | View | |
| 2026-01-05 | CFILE |
Request for Corrected Filing Receipt | 2 | View | |
| 2026-01-05 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2026-01-05 | PEFN |
Pre-Exam Formalities Notice | 1 | View | |
| 2026-01-05 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2026-01-05 | WCLM |
Claims Worksheet (PTO-2022) | 2 | View | |
| 2026-01-05 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2026-01-05 | M903 |
Notice of Designated Office (DO) / Elected Office (EO) Acceptance Mailed | 2 | View | |
| 2025-12-29 | PET.DEC.OIPE |
Petition decision routed to the Office of Patent Application Processing(OPAP) to act on the decision or continue prosecution | 2 | View | |
| 2025-11-21 | FOR |
Foreign Reference | 39 | View | |
| 2025-11-21 | FOR |
Foreign Reference | 241 | View | |
| 2025-11-21 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2025-11-21 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 6 | View | |
| 2025-11-21 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2025-08-18 | PET.PCT |
Petition for review by the PCT legal office | 4 | View | |
| 2025-08-18 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2025-08-18 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2025-08-18 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2025-08-18 | PET.PCT |
Petition for review by the PCT legal office | 2 | View | |
| 2025-08-14 | PEFN |
Pre-Exam Formalities Notice | 1 | View | |
| 2025-08-14 | ABN |
Abandonment | 1 | View | |
| 2025-07-03 | FOR |
Foreign Reference | 18 | View | |
| 2025-07-03 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2025-07-03 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 5 | View | |
| 2025-07-03 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2024-08-30 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2024-08-30 | PEFR |
Applicant Response to Pre-Exam Formalities Notice | 2 | View | |
| 2024-08-30 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2024-08-30 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2024-08-27 | 371.RES.DEF |
371 (National Stage) Defective Response - Form M916 | 2 | View | |
| 2024-08-27 | WCLM |
Claims Worksheet (PTO-2022) | 2 | View | |
| 2024-08-27 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2024-04-11 | NTC.PUB |
Notice of Publication | 1 | View | |
| 2023-12-20 | SA.. |
Supplemental Response or Supplemental Amendment | — | View | |
| 2023-12-20 | SA.. |
Supplemental Response or Supplemental Amendment | 1 | View | |
| 2023-12-20 | CLM |
Claims | 10 | View | |
| 2023-12-20 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2023-12-20 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2023-12-20 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2023-12-07 | APP.FILE.REC |
Filing Receipt | 3 | View | |
| 2023-12-04 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2023-12-04 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2023-12-04 | CFILE |
Request for Corrected Filing Receipt | 4 | View | |
| 2023-12-04 | APP.FILE.REC |
Filing Receipt | 3 | View | |
| 2023-12-04 | 371.FEE.M923 |
371 (National Stage) Supplemental Fees Missing - Form M923 | 2 | View | |
| 2023-12-04 | WCLM |
Claims Worksheet (PTO-2022) | 2 | View | |
| 2023-12-04 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2023-12-04 | WELCOME.LET |
Welcome Letter from USPTO Director and Deputy Director | 1 | View | |
| 2023-10-13 | CRFE |
Sequence Listing in Computer Readable Format, No errors found | — | View | |
| 2023-10-13 | CRFE |
Sequence Listing in Computer Readable Format, No errors found | 26 | View | |
| 2023-10-11 | PA.. |
Power of Attorney | 1 | View | |
| 2023-10-11 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2023-10-11 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2023-10-11 | OATH |
Oath or Declaration filed | 2 | View | |
| 2023-07-14 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 4 | View | |
| 2023-07-14 | A.PE |
Preliminary Amendment | 1 | View | |
| 2023-07-14 | SPEC |
Specification | 1 | View | |
| 2023-07-14 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2023-07-14 | WFEE |
Fee Worksheet (SB06) | 2 | View | |
| 2023-07-14 | N417 |
Electronic Filing System Acknowledgment Receipt | 4 | View | |
| 2023-07-14 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2023-07-14 | TRNA |
Transmittal of New Application | 4 | View | |
| 2023-07-14 | ADS |
Application Data Sheet | 8 | View | |
| 2023-07-14 | 371P |
Documents submitted with 371 (National Stage) Applications | 6 | View | |
| 2023-07-14 | CRFS |
CRF Statement that Sequence Listing text file (CRF) and paper/pdf Sequence Listing are the same | 1 | View | |
| 2023-07-14 | SPEC |
Specification | 227 | View | |
| 2023-07-14 | SPEC |
Specification | 227 | View | |
| 2023-07-14 | SEQ.TXT |
Sequence Listing (Text File) | 1 | View | |
| 2023-07-14 | 371P |
Documents submitted with 371 (National Stage) Applications | 1 | View | |
| 2023-07-14 | 371P |
Documents submitted with 371 (National Stage) Applications | 1 | View | |
| 2023-07-14 | P.N.101.CONV |
PCT/RO/101 - Request form for new International Application - Conventional | 8 | View | |
| 2023-07-14 | FRPR |
Certified Copy of Foreign Priority Application | 143 | View | |
| 2023-07-14 | ABST |
Abstract | 2 | View | |
| 2023-07-14 | CLM |
Claims | 20 | View | |
| 2023-07-14 | DRW |
Drawings-only black and white line drawings | 16 | View | |
| 2023-07-14 | ABST |
Abstract | 2 | View | |
| 2023-07-14 | SPEC |
Specification | 218 | View | |
| 2023-07-14 | CLM |
Claims | 20 | View | |
| 2023-07-14 | DRW |
Drawings-only black and white line drawings | 21 | View | |
| 2023-07-14 | SPEC |
Specification | 218 | View |
Inventors
Muthiah MANOHARAN
Cambridge, MA
Dhrubajyoti DATTA
Cambridge, MA
Attorneys & Agents of Record
Classification
USPC
514/44R
C07H19/16
C12N15/113
C07H19/167
C07H19/20
C07H21/02
C07H21/04
C12N15/111
C12N2310/14
C12N2310/315
C12N2310/333
C12N2310/343
C12N2310/344
C12N2310/3515
C12N2310/322
C12N2310/3533
C12N2310/321
C12N2310/3521
Prosecution
- Examiner
- TRAN, CHRISTINA L
- Art Unit
- 1637
- Customer No.
- 90162
- Docket No.
- 051058-099310USPX
- Confirmation No.
- 7507
Publication
- Pub. No.
- US20240116973A1
- Pub. Date
- 2024-04-11
SECURITY INTEREST
Recorded 2025-10-01
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded 2023-08-10
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Quick Facts
- App. No.
- 18/272,448
- Filed
- 2023-07-14
- Pub. No.
- US20240116973A1
- Examiner
- TRAN, CHRISTINA L
- Art Unit
- 1637
External Links