ACTIVE INGREDIENT COMPRISING OLIGO-GLUCANS DERIVED FROM THE CYTOSOLIC FRACTION OF SACCHAROMYCES CEREVISIAE, AND COSMETIC USES THEREOF
The present invention relates to an active ingredient comprising oligo-glucans, obtained from the cytosolic fraction of a yeast of the species Saccharomyces cerevisiae , a cosmetic composition comprising said active ingredient and cosmetic uses thereof, in particular to improve the regeneration of the skin and combat aging thereof.
1 . An active ingredient comprising at least one extract of Saccharomyces cerevisiae , characterized in that said extract corresponds to the cytosolic fraction comprising oligo-glucans with a molar mass of between 2 and 5 kDa.
2 . The cosmetic active ingredient according to claim 1 , characterized in that the oligo-glucans represent between 10 and 35 wt. % dry matter of the extract.
3 . The cosmetic active ingredient according to claim 2 , characterized in that the extract comprises a glucose/mannose ratio greater than 60%.
4 . The cosmetic active ingredient according to claim 1 , characterized in that the extract is a mechanical lysate of Saccharomyces cerevisiae.
5 . The cosmetic active ingredient according to claim 1 , characterized in that said extract is capable of being obtained by a method comprising the following steps:
a. solubilizing at least 50 g/l of Saccharomyces cerevisiae in water, by mechanical homogenization,
b. separating the soluble and insoluble phases,
c. ultrafiltration and recovery of the filtrate, and
d. molecular sorting.
6 . A cosmetic composition for topical application comprising at least one active ingredient according to claim 1 and a physiologically acceptable medium.
7 . The cosmetic composition according to claim 6 , wherein the active ingredient in liquid form represents at least 0.1 wt. % of the total weight of the composition.
8 . A cosmetic use of an active ingredient according to claim 1 or a cosmetic composition comprising the active ingredient, for improving skin regeneration related to normal aging of the skin.
9 . The cosmetic use according to claim 8 , characterized in that the extract or composition improves the interconnectivity of the skin, vascular and immune systems.
10 . The cosmetic use according to claim 9 , characterized in that the extract or the composition increases the synthesis and the secretion of KGF, EGF, IGF, FGF, PDGF, TGF-β and VEGF.
11 . The cosmetic use according to claim 8 for improving the radiance of the complexion.
12 . The cosmetic use according to claim 8 for preventing and/or reducing under-eye circles.
13 . The cosmetic use according to claim 8 for preventing and/or reducing wrinkles.