IP Library › Granted Patent US 12,251,120
Granted Patent B2
US 12,251,120 · App. 18/311,805 · Granted Mar 18, 2025

Devices and methods for treating vascular occlusion

Inventors: Phil Marchand (Lake Forest, CA); Benjamin E. Merritt (San Clemente, CA); John C. Thress (Capistrano Beach, CA); Jacob F. Louw (Carlsbad, CA); Paul Lubock (Monarch Beach, CA); Brian J. Cox (Laguna Nigel, CA)
Assignee: Inari Medical, Inc.
A61B17/221A61B17/320725A61F2/013A61B2017/22094A61B2017/2212A61B2017/2215A61F2/011A61F2002/016
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Quick Facts
Patent No.
US 12,251,120
App. No.
18/311,805
Granted
Mar 18, 2025
Kind
B2
Abstract

Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a fenestrated structure, a substantially cylindrical portion formed of a net-like filament mesh structure having a proximal end coupled to a distal end of the fenestrated structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction device by stacking a portion of the net-like filament mesh structure outside of the catheter by distally advancing the self-expanding member until the self-expanding member is beyond a distal end of the catheter; retracting the self-expanding member to unstack the portion of the net-like filament mesh structure and to capture the portion of the thrombus; and withdrawing the thrombus extraction device from the body.

Claims (29)

1. A method for removal of a vascular thrombus from a blood vessel of a patient, the method comprising:

positioning a thrombus extraction device entirely distal to the thrombus in the blood vessel, wherein the thrombus extraction device includes an expandable coring element and an expandable cylindrical braided mesh, and wherein a proximal portion of the cylindrical braided mesh is coupled to a distal portion of the coring element;

expanding the coring element by proximally retracting a first shaft of the thrombus extraction device relative to a second shaft of the thrombus extraction device, wherein a proximal portion of the coring element is coupled to the second shaft, and wherein the first shaft is slidably positioned within the second shaft; and

retracting the thrombus extraction device at least partially through the thrombus such that (a) the coring element separates a portion of the thrombus within the blood vessel and (b) the cylindrical braided mesh captures the portion of the thrombus.

2. The method of claim 1 wherein the coring element and the cylindrical braided mesh are formed from different materials.

3. The method of claim 1 wherein the coring element and the cylindrical braided mesh have different porosities.

4. The method of claim 1 wherein the coring element is a stent-like structure.

5. The method of claim 1 wherein the coring element is a unitary structure.

6. The method of claim 5 wherein cylindrical braided mesh comprises a plurality of filaments interwoven on the distal portion of the coring element.

7. The method of claim 1 wherein expanding the coring element includes proximally retracting the first shaft such that a feature on the first shaft engages a portion of the coring element.

8. The method of claim 1 wherein expanding the coring element includes retracting the first shaft to physically engage a feature on the first shaft with a portion of the coring element.

9. The method of claim 1 wherein positioning the thrombus extraction device includes moving the coring element relative to the cylindrical braided mesh, and wherein the method further comprises fixing a position of the cylindrical braided mesh relative to the coring element.

10. The method of claim 1 wherein retracting the thrombus extraction device at least partially through the thrombus includes at least partially receiving the portion of the thrombus through a mouth of the coring element, wherein the mouth is angled relative to a longitudinal axis of the coring element.

11. A method for removal of a vascular thrombus from a blood vessel of a patient, the method comprising:

deploying a thrombus extraction device from a delivery catheter such that the thrombus extraction device is positioned at least partially distal to the thrombus in the blood vessel, wherein the thrombus extraction device includes an expandable coring element and an expandable cylindrical braided mesh, and wherein a proximal portion of the cylindrical braided mesh is coupled to a distal portion of the coring element;

retracting the coring element proximally through the blood vessel distal of the delivery catheter relative to the cylindrical braided mesh and at least partially through the thrombus to (a) increase a length of the cylindrical braided mesh and (b) separate a portion of the thrombus from a wall of the blood vessel; and

capturing the portion of the thrombus within the cylindrical braided mesh.

12. The method of claim 11 wherein the coring element and the cylindrical braided mesh are formed from different materials.

13. The method of claim 11 wherein the coring element and the cylindrical braided mesh have different porosities.

14. The method of claim 11 wherein the coring element is a unitary structure.

15. The method of claim 14 wherein the cylindrical braided mesh comprises a plurality of filaments interwoven on the distal portion of the coring element.

16. A method for removal of a vascular thrombus from a blood vessel of a patient, the method comprising:

positioning a thrombus extraction device at least partially distal to the thrombus in the blood vessel, wherein the thrombus extraction device includes an expandable coring element and an expandable cylindrical structure;

expanding the coring element by proximally retracting a shaft of the thrombus extraction device such that a feature on the first shaft engages a portion of the coring element; and

retracting the thrombus extraction device at least partially through the thrombus such that (a) the coring element separates a portion of the thrombus within the blood vessel and (b) the cylindrical structure captures the portion of the thrombus.

17. The method of claim 16 wherein expanding the coring element includes fixing a position of the coring element while retracting the shaft of the thrombus extraction device.

18. The method of claim 16 wherein the portion of the coring element is a proximal portion of the coring element.

19. The method of claim 16 wherein the coring element is a unitary structure, and wherein the cylindrical structure is a mesh of filaments.

20. The method of claim 16 wherein the portion of the coring element includes a ring member, and wherein the feature on the first shaft is sized and shaped to engage the ring member.

Assignments (2)
NUNC PRO TUNC ASSIGNMENT Recorded Apr 29, 2026
From: INARI MEDICAL, INC.
To: STRYKER CORPORATION
Reel/Frame 075486/0805 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 17, 2023
From: MARCHAND, PHIL; MERRITT, BENJAMIN E.; THRESS, JOHN C.; LOUW, JACOB F.; LUBOCK, PAUL; COX, BRIAN J.
To: INARI MEDICAL, INC.
Reel/Frame 064279/0942 →
Continuity (5)
Continuation 17154806 · Jan 21, 2021
Continuation 16160920 · Oct 15, 2018
Continuation 15498320 · Apr 26, 2017
Provisional Application 62444705 · Jan 10, 2017
Related Publication 20230329734A1 · Oct 19, 2023
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