IP Library Granted Patent US 12,179,219
Granted Patent B2
US 12,179,219 · App. 18/313,639 · Granted Dec 31, 2024

Method and apparatus for controlling a focus point of a stationary beam focusing on a sample in a rotating cartridge placed in a rotating disc

Inventors: Ole Christian Tronrud (Sokna, NO); Rolf Jahren (Oslo, NO); Sebastian Stenmark (Oslo, NO); Stig Morten Borch (Oslo, NO)
Assignee: SpinChip Diagnostics AS
B04B13/00B01L3/502715B01L3/50273B04B5/02G01N21/07G01N35/00069G01N35/04B01L2200/0647B01L2200/143B01L2300/0803B01L2400/0409G01N2035/0491G01N2201/06113G01N2201/1087
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Quick Facts
Patent No.
US 12,179,219
App. No.
18/313,639
Granted
Dec 31, 2024
Kind
B2
Abstract

Provided are methods and apparatuses for controlling a position of a target point on a processing result relative to a focus point of a focusing sensor system for determining properties of the processing result. The method includes the steps of determining an initial focus point of the focusing sensor system, controlling rotation of the cartridge and disc, checking whether the initial focus point of the focusing sensor system corresponds to the target point on the processing result, comparing (x, y) target positions in captured images with the initial focus point of the focusing sensor system, adjusting rotation of the cartridge and disc such that the focus point of the focusing sensor system corresponds to the target point on the processing result, and detecting and examining signals received from the focusing sensor system for determining properties of the processing result.

Claims (13)

1. A method for controlling a position of a target point on a processing result relative to a focus point of a focusing sensor system for determining properties of the processing result, the method comprising the steps of:

defining a point within a cartridge as an initial focus point of a focusing sensor system, wherein the initial focus point is a point (r, θ), where r is a fraction of the radii of the cartridge and θ is the angle between a first reference point on the cartridge and the initial focus point;

controlling rotation of the cartridge and a disc such that the focus point of the focusing sensor system corresponds to the initial focus point by determining angular positions φ and Θ to be set for the cartridge and the disc such that the initial focus point of the focusing sensor system corresponds to the point (r, θ) within the cartridge, wherein angle Θ of the cartridge is determined relative to the first reference point on the cartridge and angle q of the disc is determined relative to a second reference point on the disc;

checking whether the initial focus point of the focusing sensor system corresponds to the target point on the processing result by capturing images of the processing result in the cartridge and the initial focus point within the cartridge, and comparing (x, y) target positions in captured images with the initial focus point of the focusing sensor system, and adjusting rotation of the cartridge and disc such that the focus point of the focusing sensor system corresponds to the target point on the processing result; and

iteratively detecting properties of the processing result by turning the disk and cartridge in equispaced steps from the target point such that an area of the processing result is scanned by the focus point of the focusing sensor system.

2. The method of claim 1 , wherein capturing images of the processing result comprises capturing images with a camera.

3. The method of claim 2 , comprising illuminating the cartridge by spread light from a spread light source for improving exposure of images captured by the camera.

4. The method of claim 3 , comprising positioning the spread light source below the cartridge and positioning the camera above the cartridge.

5. The method of claim 3 , wherein the spread light source comprises an LED.

6. The method of claim 1 , comprising, if the initial focus point of the focusing sensor system does not correspond to the target point of the processing result, performing incremental rotation of the cartridge and the disc until a focus point of the focusing sensor system corresponds to the target point of a processing result.

7. The method of claim 1 , further comprising averaging or integrating the iteratively detected properties of the processing result from the area of the processing result scanned by the focus point of the focusing sensor system.

8. The method of claim 1 , wherein the focusing sensor system comprises a beam light source.

9. The method of claim 8 , wherein the beam light source comprises a laser.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 18, 2026
From: SPINCHIP DIAGNOSTICS AS
To: BIOMÉRIEUX
Reel/Frame 074683/0628 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 8, 2023
From: TRONRUD, OLE CHRISTIAN; JAHREN, ROLF; STENMARK, SEBASTIAN; BORCH, STIG MORTEN
To: SPINCHIP DIAGNOSTICS AS
Reel/Frame 064852/0489 →
Priority Claims (1)
NO 20171780 · Nov 9, 2017 · national
Continuity (2)
Division 16761459
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