IP Library Granted Patent US 12,105,175
Granted Patent B2
US 12,105,175 · App. 18/333,358 · Granted Oct 1, 2024

Artefact reduction in magnetic resonance imaging

Inventors: Carole Lazarus (Paris, FR); Rafael O'Halloran (Guilford, CT); Hadrien A. Dyvorne (New York, NY)
Assignee: Hyperfine Operations, Inc.
G01R33/56509G01R33/3628G01R33/4818G01R33/4822G01R33/5608G01R33/5611G01R33/56518G06T11/006G06T11/008
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Quick Facts
Patent No.
US 12,105,175
App. No.
18/333,358
Granted
Oct 1, 2024
Kind
B2
Abstract

Techniques of prospectively compensating for motion of a subject being imaged by an MRI system, the MRI system comprising a plurality of magnetics components including at least one gradient coil and at least one radio-frequency (RF) coil, the techniques comprising: obtaining first spatial frequency data and second spatial frequency data by operating the MRI system in accordance with a pulse sequence, wherein the pulse sequence is associated with a sampling path that includes at least two non-contiguous portions each for sampling a central region of k-space; determining a transformation using a first image obtained using the first spatial frequency data and a second image obtained using the second spatial frequency data; correcting the pulse sequence using the determined transformation to obtain a corrected pulse sequence; and obtaining additional spatial frequency data in accordance with the corrected pulse sequence.

Claims (46)

1. A method comprising:

obtaining spatial frequency data by operating an MRI system in accordance with a pulse sequence;

identifying, from the spatial frequency data and based on information indicating a time or times of movement of a subject being imaged by the MRI system, first spatial frequency data and second spatial frequency data;

determining a transformation using a first image obtained using the first spatial frequency data and a second image obtained using the second spatial frequency data;

correcting the pulse sequence using the determined transformation to obtain a corrected pulse sequence; and

obtaining additional spatial frequency data in accordance with the corrected pulse sequence.

2. The method of claim 1 , further comprising: generating at least one magnetic resonance (MR) image using the additional spatial frequency data.

3. The method of claim 2 , wherein generating the at least one MR image is performed using the first spatial frequency data, the second spatial frequency data, and the additional spatial frequency data.

4. The method of claim 2 , wherein generating the at least one MR image is performed using an iterative reconstruction technique.

5. The method of claim 1 , wherein the pulse sequence is associated with a sampling path that includes at least two non-contiguous portions each for sampling a central region of k-space.

6. The method of claim 5 , wherein the central region of k-space is a region located entirely within a threshold distance of an origin of k-space.

7. The method of claim 5 , wherein the central region comprises a two-dimensional (2D) elliptical, circular, rectangular, and/or square region that includes an origin of k-space.

8. The method of claim 5 , wherein the sampling path comprises multiple noncontiguous sub-paths containing k-space phase-encoding coordinates in the central region.

9. The method of claim 1 , wherein the transformation is a rigid transformation.

10. The method of claim 1 , wherein the transformation comprises a rotation and a translation.

11. The method of claim 1 ,

wherein the pulse sequence comprises a gradient waveform,

wherein correcting the pulse sequence comprises determining a corrected gradient waveform from the gradient waveform by using the determined transformation, and

wherein obtaining the additional spatial frequency data in accordance with the corrected pulse sequence comprises operating the MRI system in accordance with the corrected gradient waveform.

12. The method of claim 11 ,

wherein the transformation comprises a rotation, and

wherein determining the corrected gradient waveform comprises applying the rotation to the gradient waveform.

13. The method of claim 1 ,

wherein the transformation comprises a translation, and

wherein correcting the pulse sequence comprises changing transmit frequency of the at least one RF coil and/or receive phase of the at least one RF coil.

14. The method of claim 1 , wherein the method prospectively compensates for motion of the subject being imaged by the MRI system, the MRI system comprising a plurality of magnetics components including at least one gradient coil and at least one radio-frequency (RF) coil.

15. A magnetic resonance imaging (MRI) system comprising:

at least one controller configured to perform:

controlling the MRI system in accordance with an MRI pulse sequence to obtain spatial frequency data;

identifying, from the spatial frequency data and based on information indicating a time or times of movement of a subject, first spatial frequency data and second spatial frequency data;

determining a transformation using a first image obtained using the first spatial frequency data and a second image obtained using the second spatial frequency data;

correcting the pulse sequence using the determined transformation to obtain a corrected pulse sequence; and

controlling the MRI system to obtain additional spatial frequency data in accordance with the corrected pulse sequence.

16. The MRI system of claim 15 , wherein the at least one controller is further configured to perform:

generating at least one magnetic resonance (MR) image using the additional spatial frequency data.

17. The MRI system of claim 15 , wherein the pulse sequence is associated with a sampling path that repeatedly samples a central region of k-space, wherein the central region of k-space is a region located entirely within a threshold distance of an origin of k-space, wherein the sampling path comprises multiple non-contiguous sub-paths containing k-space phase-encoding coordinates in the central region, and wherein the transformation comprises a rotation and a translation.

18. The MRI system of claim 15 ,

wherein the pulse sequence comprises a gradient waveform,

wherein correcting the pulse sequence comprises determining a corrected gradient waveform from the gradient waveform by using the determined transformation, and

wherein obtaining the additional spatial frequency data in accordance with the corrected pulse sequence comprises operating the MRI system in accordance with the corrected gradient waveform.

19. The MRI system of claim 18 , wherein determining the corrected gradient waveform comprises applying a rotation to the gradient waveform.

20. The MRI system of claim 15 , further comprising:

a plurality of magnetics components including:

at least one gradient coil; and

at least one RF coil;

wherein correcting the pulse sequence comprises changing transmit frequency of the at least one RF coil and/or receive phase of the at least one RF coil.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 12, 2023
From: LAZARUS, CAROLE; O'HALLORAN, RAFAEL; DYVORNE, HADRIEN A.
To: HYPERFINE RESEARCH, INC.
Reel/Frame 063926/0147 →
CHANGE OF NAME Recorded Jun 12, 2023
From: HYPERFINE RESEARCH, INC.
To: HYPERFINE, INC.
Reel/Frame 063982/0514 →
CHANGE OF NAME Recorded Jun 12, 2023
From: HYPERFINE, INC.
To: HYPERFINE OPERATIONS, INC.
Reel/Frame 063982/0568 →
Continuity (3)
Continuation 17078788 · Oct 23, 2020
Provisional Application 62925924 · Oct 25, 2019
Related Publication 20230341494A1 · Oct 26, 2023