Granted Patent B2

US 12,623,080 · App. 18/339,085 · Granted May 12, 2026

Inventor: Yoann Dumény (Lausanne, CH)

Assignee: Onward Medical N.V.

A61N1/36146A61N1/37211

Abstract

Claims (60)

1 . A neuromodulation system, comprising:

an implantable pulse generator configured to provide neuromodulation to a patient based on a sequence of neuromodulation programs, the implantable pulse generator comprising alternately accessible memories; and

wherein

a second memory of the memories is configured for receiving and storing a second neuromodulation program of the sequence of neuromodulation programs while the implantable pulse generator provides neuromodulation according to a first neuromodulation program of the sequence of neuromodulation programs, the first neuromodulation program stored in a first memory of the memories.

2 . The neuromodulation system of claim 1 , wherein the sequence of neuromodulation programs is configured to enable one or more functions selected from a group consisting of postural and/or locomotor activity, upper and/or lower limb activity, voluntary voiding of the bladder and/or bowel, sexual function, autonomic control of cardiovascular function, respiratory and/or coughing function, body temperature control, and normalized metabolic processes.

3 . The neuromodulation system of claim 1 , wherein:

the implantable pulse generator is further configured to receive the first neuromodulation program and the second neuromodulation program from a programmer that stores the sequence of neuromodulation programs.

4 . The neuromodulation system of claim 3 , further comprising:

a controller configured to maintain a communication link with the implantable pulse generator.

5 . The neuromodulation system of claim 4 , wherein:

the implantable pulse generator is further configured to cease providing the neuromodulation when the communication link fails for a period of time.

6 . The neuromodulation system of claim 5 , wherein the period of time is in a range of 0.1 second to 5 minutes.

7 . The neuromodulation system of claim 5 , wherein the period of time is in a range of 0.1 second to 60 seconds.

8 . The neuromodulation system of claim 1 , wherein:

the implantable pulse generator is further configured to:

receive, from the programmer, an update instruction specifying an update of a stimulation parameter;

store, in a parameter memory, the update of the stimulation parameter;

access, in the parameter memory during provision of the neuromodulation according to a first neuromodulation program, the update of the stimulation parameter; and

provide a next pulse of the neuromodulation based on the stimulation parameter.

9 . The neuromodulation system of claim 8 , wherein the stimulation parameter comprises at least one of intensity, amplitude, pulse width, pulse ratio, electrode configuration, frequency, carrier frequency, or burst frequency.

10 . The neuromodulation system of claim 1 , wherein the second memory of the memories is configured for storing the second neuromodulation program according to a second state machine associated with the second memory, wherein:

when the second state machine is in a first state, the second memory is accessible for writing the second neuromodulation program;

the second state machine is in a second state when the second neuromodulation program is being written to the second memory;

when the second state machine is in a third state, the second memory is accessible for reading the second neuromodulation program; and

the second state machine is in a fourth state when the second neuromodulation program is being read from the second memory.

11 . The neuromodulation system of claim 10 , wherein:

the second state machine transitions from the first state to the second state in response to an update request;

the second state machine transitions from the second state to the third state upon completion of the update request; and

the second state machine transitions from the third state to the fourth state in response to an execution request upon completion of the neuromodulation provided according to the first neuromodulation program.

12 . The neuromodulation system of claim 11 , wherein a latency between receiving an update request and providing stimulation according to the request is less than 100 millisecond.

13 . The neuromodulation system of claim 11 , wherein a latency between receiving an update request and providing stimulation according to the request is less than 50 milliseconds.

14 . The neuromodulation system of claim 10 , wherein:

completion of the neuromodulation according to the first neuromodulation program depends upon a repeat value associated with the first neuromodulation program.

15 . A method for providing neuromodulation according to a sequence of neuromodulation programs, comprising:

receiving, by the implantable pulse generator and during provision of neuromodulation according to a first neuromodulation program in the sequence of neuromodulation programs, the first neuromodulation program read from a first memory of the implantable pulse generator, a second neuromodulation program in the sequence of neuromodulation programs;

storing, in a second memory of the implantable pulse generator, the second neuromodulation program; and

providing, by the implantable pulse generator and upon completion of the provision of the neuromodulation according to the first neuromodulation program, neuromodulation according to the second neuromodulation program stored in the second memory.

16 . The method of claim 15 , wherein the first neuromodulation program and the second neuromodulation program are received from a programmer that stores the sequence of neuromodulation programs.

17 . The method of claim 15 , wherein the method further comprises:

receiving, by the programmer from a user, an instruction corresponding to the sequence of neuromodulation programs;

providing, by the programmer in response to the receipt of the instruction, the first neuromodulation program, and

wherein the instruction enables one or more functions selected from a group consisting of postural and/or locomotor activity, upper and/or lower limb activity, voluntary voiding of the bladder and/or bowel, sexual function, autonomic control of cardiovascular function, respiratory and/or coughing function, body temperature control, and normalized metabolic processes.

18 . The method of claim 15 , wherein the method further comprises:

a controller configured to maintain a communication link with the implantable pulse generator.

19 . The method of claim 15 , the method further comprises:

ceasing provision of the neuromodulation, by the implantable pulse generator, when the communication link fails for a period of time.

20 . The method of claim 15 , the method further comprises:

receiving, by the implantable pulse generator and during the provision of the neuromodulation according to the first neuromodulation program, an update instruction specifying an update of a stimulation parameter;

storing, in a parameter memory, the update of the stimulation parameter;

accessing, in the parameter memory during provision of the neuromodulation according to a first neuromodulation program, the update of the stimulation parameter; and

providing, by the implantable pulse generator, a next pulse of the neuromodulation based on the stimulation parameter.

21 . The method of claim 20 , wherein the stimulation parameter comprises at least one of intensity, amplitude, pulse width, pulse ratio, electrode configuration, frequency, carrier frequency, or burst frequency.

22 . The method of claim 15 , wherein:

storing the second neuromodulation program comprises storing the second neuromodulation program according to a second state machine associated with the second memory, the second state machine configured to:

enable writing to the second memory when the second state machine is in a first state; and

transition from the first state to a second state in response to an update request to write the second neuromodulation program to the second memory; and

providing the neuromodulation according to the second neuromodulation program comprises accessing the second memory according to the second state machine, the second state machine configured to:

enable access to the second memory when the second state machine is in a third state; and

transition from the third state to a fourth state in response to an execution request to provide neuromodulation according to the second neuromodulation program.

23 . The method of claim 21 , wherein the execution request is provided based on a repeat value associated with the first neuromodulation program.

Assignments (3)

Continuity (1)

References Cited (400)