IP Library › Granted Patent US 12,285,592
Granted Patent B2
US 12,285,592 · App. 18/343,305 · Granted Apr 29, 2025

Infusion devices and related methods and systems for preemptive alerting

Inventors: Cesar C. Palerm (Pasadena, CA); Jeffrey C. Myers (Moorpark, CA)
Assignee: MEDTRONIC MINIMED, INC.
A61M5/16831A61B5/14532A61B5/4839A61B5/7275A61M5/1723G16H20/17A61M2205/18
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Quick Facts
Patent No.
US 12,285,592
App. No.
18/343,305
Granted
Apr 29, 2025
Kind
B2
Abstract

Techniques disclosed herein relate to infusion devices and alerts. In some embodiments, the techniques may involve identifying an amount of future insulin deliveries to be delivered by an infusion device. The techniques may further involve determining a homeostasis metric by predicting a change in a current glucose measurement value based on accounting for metabolism of a current amount of active insulin and the amount of future insulin deliveries. The techniques may further involve generating an alert based at least in part on the homeostasis metric.

Claims (37)

1. A method for insulin therapy, the method comprising:

identifying an amount of future insulin deliveries to be delivered by an infusion device;

determining a homeostasis metric by predicting a change in a current glucose measurement value based on accounting for metabolism of a current amount of active insulin and the amount of future insulin deliveries; and

generating an alert based at least in part on the homeostasis metric.

2. The method of claim 1 , wherein:

the homeostasis metric comprises an estimated correction bolus amount determined based at least in part on the current amount of active insulin in a body of a user, the current glucose measurement value, the amount of future insulin deliveries, and a target glucose value; and

the alert comprises a graphical notification of the estimated correction bolus amount.

3. The method of claim 1 , wherein:

the homeostasis metric comprises an excess insulin amount determined based at least in part on the current amount of active insulin in a body of a user, the current glucose measurement value, the amount of future insulin deliveries, and a target glucose value; and

the alert comprises a graphical notification of a recommended amount of carbohydrates to offset the excess insulin amount.

4. The method of claim 1 , wherein the homeostasis metric comprises an estimated correction bolus amount determined based at least in part on the current amount of active insulin in a body of a user, the current glucose measurement value, the amount of future insulin deliveries, and a target glucose value, the method further comprising adjusting the homeostasis metric by multiplying the estimated correction bolus amount by a trend adjustment factor.

5. The method of claim 4 , further comprising determining the trend adjustment factor based on a difference between the current glucose measurement value and a previous glucose measurement value.

6. The method of claim 4 , wherein generating the alert comprises generating the alert when the estimated correction bolus amount is greater than an alert threshold value.

7. The method of claim 1 , further comprising suppressing or disabling the alert when a predicted value for a glucose level of a user exceeds an upper threshold value and the homeostasis metric is less than an alert threshold value.

8. The method of claim 1 , wherein the current glucose measurement value is a first glucose measurement value, the method further comprising:

after generating the alert, obtaining a second glucose measurement value of a user; and

automatically clearing the alert based at least in part on the second glucose measurement value.

9. The method of claim 8 , wherein automatically clearing the alert comprises automatically clearing the alert when the second glucose measurement value is greater than a hyperglycemic alert threshold.

10. The method of claim 9 , further comprising automatically providing a hyperglycemic alert in lieu of the alert when the second glucose measurement value is greater than the hyperglycemic alert threshold.

11. The method of claim 8 , wherein automatically clearing the alert comprises automatically clearing the alert when the second glucose measurement value is less than a hypoglycemic alert threshold.

12. The method of claim 11 , further comprising automatically providing a hypoglycemic alert in lieu of the alert when the second glucose measurement value is less than the hypoglycemic alert threshold.

13. The method of claim 8 , further comprising operating the infusion device to deliver a dosage of insulin to a user based at least in part on the current glucose measurement value, wherein the second glucose measurement value is obtained after operating the infusion device to deliver the dosage.

14. The method of claim 1 , wherein the homeostasis metric comprises an estimated correction bolus amount for maintaining a user's future glucose level at or near a target glucose level.

15. The method of claim 14 , wherein the estimated correction bolus amount is indicative of whether the user needs additional insulin to account for carbohydrates consumed by the user to maintain his or her glucose level at or near the target glucose level.

16. The method of claim 1 , wherein the homeostasis metric comprises an expected glucose measurement value at a subsequent time after a correction bolus, the expected glucose measurement value being indicative of whether the correction bolus is having its anticipated effect on a user's glucose level.

17. The method of claim 1 , wherein the homeostasis metric comprises an estimated amount of excess insulin determined based on an expected glucose measurement value after all delivered insulin is metabolized.

18. The method of claim 1 , wherein the current glucose measurement value is obtained from a sensing arrangement.

19. One or more non-transitory processor-readable media storing instructions which, when executed by one or more processors, cause performance of:

identifying an amount of future insulin deliveries to be delivered by an infusion device;

determining a homeostasis metric by predicting a change in a current glucose measurement value based on accounting for metabolism of a current amount of active insulin and the amount of future insulin deliveries; and

generating an alert based at least in part on the homeostasis metric.

20. A system comprising:

one or more processors; and

one or more processor-readable media storing instructions which, when executed by one or more processors, cause performance of:

identifying an amount of future insulin deliveries to be delivered by an infusion device;

determining a homeostasis metric by predicting a change in a current glucose measurement value based on accounting for metabolism of a current amount of active insulin and the amount of future insulin deliveries; and

generating an alert based at least in part on the homeostasis metric.

Assignments (2)
SECURITY INTEREST Recorded Jan 16, 2026
From: MEDTRONIC MINIMED, INC.; COMPANION MEDICAL, INC.
To: CITIBANK, N.A.
Reel/Frame 074394/0237 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 29, 2023
From: PALERM, CESAR C.; MYERS, JEFFREY C.
To: MEDTRONIC MINIMED, INC.
Reel/Frame 064118/0623 →
Continuity (4)
Continuation 17457165 · Dec 1, 2021
Continuation 16387297 · Apr 17, 2019
Division 14578174 · Dec 19, 2014
Related Publication 20230338651A1 · Oct 26, 2023
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