IP Library Granted Patent US 12,617,743
Granted Patent B2
US 12,617,743 · App. 18/345,462 · Granted May 5, 2026

Process for preparing the dialdehyde of vinylcyclohexene

Inventors: Robert Franke (Marl, DE); Carolin Schneider (Monheim am Rhein, DE); Ralf Jackstell (Rostock, DE); Matthias Beller (Ostseebad Nienhagen, DE)
Assignee: EVONIK OXENO GMBH & CO. KG
C07C45/60B01J27/13C07C29/14C07C31/276C07C47/32C07C2601/14
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Quick Facts
Patent No.
US 12,617,743
App. No.
18/345,462
Granted
May 5, 2026
Kind
B2
Abstract

Process for preparing the dialdehyde of vinylcyclohexene.

Claims (30)

1 . Process comprising the process steps of:

a) initially charging vinylcyclohexene;

b) adding a compound of formula (I):

where R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 are selected from: —H, —(C 1 -C 12 )-alkyl, -Ph;

c) adding a Pt compound capable of forming a complex;

d) adding an iodine compound;

e) feeding in CO and H 2 ;

f) heating the reaction mixture from steps a) to e), to convert the vinylcyclohexene to the dialdehyde and

g) converting the dialdehyde to the diol.

2 . Process according to claim 1 ,

where R 1 and R 4 are —H.

3 . Process according to claim 1 ,

where R 5 , R 6 , R 7 , R 8 are -Ph.

4 . Process according to claim 1 ,

where R 2 and R 3 are —(C 1 -C 12 )-alkyl.

5 . Process according to claim 1 ,

where R 2 and R 3 are —CH 3 .

6 . Process according to claim 1 ,

wherein the compound (I) has the structure (1):

7 . Process according to claim 1 ,

wherein the Pt compound is selected from: Pt(II)I 2 , Pt(IV)I 4 , diphenyl(1,5-COD)Pt(II), Pt(II)(acac) 2 , Pt(0)(PPh 3 ) 4 , Pt(0)(DVTS) solution (CAS: 68478-92-2), Pt(0)(ethylene)(PPh 3 ) 2 , tris(benzylideneacetone)Pt(0), Pt(II)(OAC) 2 solution, Pt(0)(t-Bu) 2 , Pt(II)(COD)Me 2 , Pt(II)(COD)I 2 , Pt(IV)IMe 3 , Pt(II)(hexafluoroacetylacetonate) 2 .

8 . Process according to claim 1 ,

wherein PtI 2 is added in an amount, measured in mol % based on vinylcyclohexene, so that the value is in the range of 0.1 mol % to 5 mol %.

9 . Process according to claim 1 ,

comprising the additional process step e′):

e′) adding a solvent.

10 . Process according to claim 1 ,

wherein the conversion of the dialdehyde to the diol is carried out using “Shvo's catalyst” (CAS 104439-77-2).

11 . Aldehyde mixture comprising the compounds (2a) and (2b):

12 . Alcohol mixture comprising the compounds (3a) and (3b):

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 9, 2024
From: EVONIK OPERATIONS GMBH
To: EVONIK OXENO GMBH & CO. KG
Reel/Frame 066242/0585 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 2, 2023
From: FRANKE, ROBERT; SCHNEIDER, CAROLIN; JACKSTELL, RALF; BELLER, MATTHIAS
To: EVONIK OPERATIONS GMBH
Reel/Frame 065091/0347 →
Priority Claims (1)
EP 22183349 · Jul 6, 2022 · regional
Continuity (1)
Related Publication 20240010593A1 · Jan 11, 2024
References Cited (31)
US 6252121B1 · Argyropoulos et al. · 2001 [cited by applicant]
US 20050164874A1 · Tsuji · 2005 [cited by applicant]
US 20090171125A1 · Shih et al. · 2009 [cited by applicant]
US 20110009548A1 · Dakka et al. · 2011 [cited by applicant]
US 20230192582A1 · Schneider et al. · 2023 [cited by applicant]
US 20240010593A1 · Franke et al. · 2024 [cited by applicant]
AT 192395B · 1957 [cited by applicant]
CN 1087078A · 1994 [cited by applicant]
EP 0577042A1 · 1994 [cited by applicant]
EP 1065194A1 · 2001 [cited by applicant]
EP 4198002A1 · 2023 [cited by applicant]
GB 1368434 · 1974 [cited by applicant]
JP S5350102A · 1978 [cited by applicant]
JP 2003505438A · 2003 [cited by applicant]
JP 2012188413A · 2012 [cited by applicant]
JP 7585398B2 · 2024 [cited by applicant]
WO 0107382A2 · 2001 [cited by applicant]
WO 2011005822A1 · 2011 [cited by applicant]
European Search Report dated Jan. 4, 2023 for European Patent Application No. 22183349.2 (7 pages in German with Machine Translation). [cited by applicant]
Petöcz, G., et al. Xantphos as cis- and trans-chelating ligand in square-planar platinum(II) complexes. Hydroformylation of styrene with platinum-xantphos-tin(II)chloride system. Journal of Organometallic Chemistry. 200… [cited by applicant]
Garlaschelli, Luigi, et al. Hydroformylation and hydrocarbonylation of dicyclopentadiene with cobalt-rhodium catalytic systems promoted by triphenylphosphine: synthesis of monoformyltryclodecenes, diformyltricyclodecane… [cited by applicant]
Van Leeuwen, Piet W.N.M. Xantphos-based, silica-supported, selective, and recyclable hydroformylation catalysts: a review. Journal of Molecular Catalysis A: Chemical. 2002 vol. 182-183, pp. 107-123. [cited by applicant]
Notice of Reasons for Refusal mailed May 28, 2024 for Japanese Patent Application No. 2023-108019 (4 pages in Japanese; 4 pages English translation). [cited by applicant]
Arena, Carmela G., et al. Rhodium(I), Palladium(II), and Platinum(II) Complexes Containing New Mixed Phosphane—Phosphite Ligands—Effect of the Catalytic System Stability on the Enantioselective Hydroformylation of Styre… [cited by applicant]
Chinese Office Action mailed May 29, 2025 for Chinese Patent Application No. 202310801297.0 (7 pages in Chinese; 5 pages English translation). [cited by applicant]
CAS No. 104439-77-2. Tetracarbonyl-μ-hydro[(1,2,3,4,5-η)-1-hydroxylato-2,3,4,5-tetraphenyl-2,4-cyclopentadien-1-yl][(1,2,3,4,5-η)-1-hydroxy-2,3,4,5-tetraphenyl-2,4-cyclopentadien-1-yl]diruthenium. Accessed Jun. 30, 2023… [cited by applicant]
CAS No. 68478-92-2. Platinum, 1,3-diethenyl-1,1,3,3-tetramethyldisiloxane complexes. Accessed Jun. 30, 2023. 2 Pages. https://commonchemistry.cas.org/detail?cas_rn-68478-92-2&search=68478-92-2. [cited by applicant]
CAS No. 104439-77-2. SHVO's Catalyst. Accessed Jun. 30, 2023. 2 Pages. https://www.chemicalbook.com/ChemicalProductProperty_EN_CB2246930.htm. [cited by applicant]
CAS No. 68478-92-2. Karstedt Catalyst. Platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane. Accessed Jun. 30, 2023. 4 Pages. https://www.chemicalbook.com/CASEN_68478-92-2.htm. [cited by applicant]
Fuchs, Sarah, et al. Synthesis of Industrial Primary Diamines via Intermediate Diols—Combining Hydroformylation, Hydrogenation and Amination. ChemCatChem. 2018. vol. 10, pp. 4126-4133. [cited by applicant]
Examination Report mailed Dec. 5, 2025 for Indian Patent Application No. 202314043866 (9 pages). [cited by applicant]