Devices, assemblies, and methods for delivering agents
A valve assembly for a medical device that includes a piston configured to move relative to an enclosure of the medical device, the enclosure including a first region in fluid communication with an agent, and a second region in fluid communication with a source of fluid. The piston includes a chamber disposed on a sidewall of the piston which is configured to receive the agent. The piston is configured to move to a first position where the chamber is in fluid communication with the first region and not in fluid communication with the second region such that the agent is received within the chamber, and further configured to move to a second position where the chamber is in fluid communication with the second region and not in fluid communication with the first region, such that the agent within the chamber is mixed with the fluid received in the second region.
1 . A valve assembly for a medical device, comprising:
a piston configured to move relative to an enclosure of the medical device, the enclosure including a first region that is in fluid communication with an agent, and a second region including a porous funnel that is in fluid communication with a source of fluid, the piston including a chamber disposed on a sidewall of the piston, wherein the chamber is configured to receive the agent;
wherein the piston is configured to move to a first position relative to the enclosure with the chamber in fluid communication with the first region and not in fluid communication with the second region, such that the agent is received within the chamber; and
wherein the piston is configured to move to a second position relative to the enclosure with the chamber in fluid communication with the second region and not in fluid communication with the first region, such that the fluid received in the second region passes through the porous funnel to mix with the agent received in the chamber, thereby controlling delivery of the agent and the fluid from the medical device.
2 . The valve assembly of claim 1 , wherein the chamber comprises a closed cavity within the sidewall of the piston.
3 . The valve assembly of claim 2 , wherein the closed cavity has a hemispherical-shape.
4 . The valve assembly of claim 1 , wherein the piston is configured to move to a third position relative to the enclosure, wherein in the third position, the piston is transitioned to an intermediary region disposed between the first region and the second region, and wherein the intermediary region is not in fluid communication with either of the first region or the second region.
5 . The valve assembly of claim 4 , wherein the intermediary region is configured to seal the chamber when the piston is in the third position.
6 . The valve assembly of claim 1 , wherein the piston is coupled to an actuation mechanism of the medical device, the actuation mechanism is configured to move the piston relative to the enclosure for delivering the agent from the first region to the second region.
7 . The valve assembly of claim 6 , wherein the actuation mechanism comprises a pneumatic system, the pneumatic system comprising a piston rod and a spring.
8 . The valve assembly of claim 7 , wherein a proximal end of the piston is coupled to the piston rod.
9 . The valve assembly of claim 6 , wherein the piston is configured to be biased to the first position with the chamber received within the first region.
10 . The valve assembly of claim 1 , wherein the chamber is sized to define a volume that corresponds to a predetermined volume of the agent.
11 . The valve assembly of claim 1 , wherein the enclosure includes the porous funnel positioned within the second region, and the piston is configured to release the agent onto an interior surface of the porous funnel when in the second position.
12 . The valve assembly of claim 11 , wherein the porous funnel is in fluid communication with the source of fluid via a plurality of passages formed between the interior surface and an exterior surface of the porous funnel, and the plurality of passages extend along a length of the porous funnel such that the fluid received in the second region passes through the plurality of passages of the porous funnel for mixing with the agent.
13 . The valve assembly of claim 12 , wherein the porous funnel is configured to deliver the agent and the fluid to a delivery conduit of the medical device that is in fluid communication with the second region when the agent and the fluid are mixed along the porous funnel.
14 . The valve assembly of claim 1 , further comprising an outlet coupled to the second region.
15 . The valve assembly of claim 14 , further comprising a catheter coupled to the outlet, wherein the agent is released into the catheter via the outlet.
16 . A device for delivering an agent, comprising:
a pressurized fluid source configured to store a pressurized fluid;
an enclosure configured to store the agent, the enclosure including an inlet region in fluid communication with the agent and an outlet region having a porous funnel that is in fluid communication with the pressurized fluid source; and
a valving assembly disposed within the enclosure, the valving assembly including a piston having a chamber disposed along a sidewall of the piston, wherein the piston is configured to move between a first position and a second position relative to the enclosure to selectively guide the agent from the inlet region to the outlet region;
wherein, in the first position, the chamber is positioned within the inlet region such that the piston is configured to receive the agent in the chamber; and
wherein, in the second position, the chamber is positioned within the outlet region such that the piston is configured to release the agent from the chamber to mix with the pressurized fluid received from the pressurized fluid source and passing through the porous funnel.
17 . The device of claim 16 , wherein the piston is configured to move to a third position relative to the enclosure;
wherein, in the first position, the piston is fully disposed within the inlet region such that the chamber is in fluid communication with the inlet region,
wherein, in the third position, the piston is positioned within an intermediary region disposed between the inlet region and the outlet region such that the chamber is not in fluid communication with the agent in the inlet region and the pressurized fluid in the outlet region; and
wherein, in the second position, the piston is positioned within the outlet region such that the chamber is in fluid communication with the outlet region.
18 . The device of claim 17 , wherein the chamber is configured to receive a volume of the agent when the piston is in the first position.
19 . The device of claim 18 , wherein the chamber is configured to release the volume of the agent when the piston is in the second position.
20 . A method of delivering an agent from a medical device, the method comprising:
moving a piston to a first region of an enclosure of the medical device, the first region is in fluid communication with a source of the agent such that a chamber disposed on a sidewall of the piston receives a volume of the agent when the piston is in the first region;
moving the piston to a second region of the enclosure, thereby releasing the volume of the agent received in the chamber into the second region, wherein the second region is in fluid communication with a source of fluid and the enclosure includes a porous funnel within the second region;
releasing fluid into the second region from the source of fluid through the porous funnel, thereby mixing the volume of the agent with the fluid within the second region; and
delivering a mixture of the volume of the agent and the fluid from the second region through an outlet of the medical device that is in fluid communication with the second region.