IP Library › Granted Patent US 12,285,611
Granted Patent B2
US 12,285,611 · App. 18/366,619 · Granted Apr 29, 2025

Spinal cord modulation for inducing paresthetic and anesthetic effects, and associated systems and methods

Inventors: Konstantinos Alataris (Belmont, CA); Andre B. Walker (Monte Sereno, CA); Jon Parker (Portland, OR)
Assignee: Nevro Corp.
A61N1/36071A61N1/36021A61N1/36132A61N1/3615A61N1/36171A61N1/36178A61N1/06
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Quick Facts
Patent No.
US 12,285,611
App. No.
18/366,619
Granted
Apr 29, 2025
Kind
B2
Abstract

Spinal cord modulation for inducing paresthetic and anesthetic effects, and associated systems and methods are disclosed. A representative method in accordance with an embodiment of the disclosure includes creating a therapeutic effect and a sensation in a patient by delivering to the patient first pulses having a first set of first signal delivery parameters and second pulses having a second set of second signal delivery parameters, wherein a first value of at least one first parameter of the first set is different than a second value of a corresponding second parameter of the second set, and wherein the first pulses, the second pulses or both the first and second pulses are delivered to the patient's spinal cord.

Claims (20)

1. A method for configuring a patient treatment system to deliver a therapy signal to a target neural population at a patient's spinal cord, the method comprising:

programming a signal generator of the patient treatment system to generate bursts of high frequency pulses, wherein each burst of high frequency pulses includes at least two high frequency pulses having a frequency in a frequency range of from 1.5 kHz to 100 kHz, and wherein the bursts of high frequency pulses do not generate paresthesia when delivered to the target neural population.

2. The method of claim 1 wherein the frequency range is from 1.5 kHz to 50 kHz.

3. The method of claim 1 wherein the frequency range is from 5 kHz to 15 kHz.

4. The method of claim 1 wherein the frequency is 10 kHz.

5. The method of claim 1 wherein individual high frequency pulses have a pulse width in a pulse width range of from 10 microseconds to 333 microseconds.

6. The method of claim 1 wherein individual high frequency pulses have an amplitude in an amplitude range of from 0.1 mA to 10 mA.

7. The method of claim 1 wherein the at least two high frequency pulses are separated by an interpulse interval of up to 15 microseconds.

8. The method of claim 1 wherein the bursts of high frequency pulses have a duty cycle of 85%.

9. The method of claim 1 wherein the bursts of high frequency pulses have a duty cycle of 60%.

10. The method of claim 1 wherein each of the at least two high frequency pulses are bi-phasic.

11. The method of claim 1 wherein the frequency range is from 1.5 kHz to 50 kHz.

12. A patient treatment system, comprising:

an implantable signal delivery device implantable proximate a target neural population at a patient's spinal cord; and

a pulse generator coupleable to the implantable signal delivery device, wherein the pulse generator, in operation:

generates bursts of high frequency pulses, wherein each burst of high frequency pulses includes at least two high frequency pulses having a frequency in a frequency range of from 1.5 kHz to 100 kHz, and

directs the bursts of high frequency pulses to the target neural population via the implantable signal delivery device, wherein the bursts of high frequency pulses do not generate paresthesia when delivered to a patient.

13. The system of claim 12 wherein individual high frequency pulses have (i) a pulse width in a pulse width range of from 10 microseconds to 333 microseconds, and (ii) an amplitude in an amplitude range of from 0.1 mA to 10 mA.

14. The system of claim 12 wherein each of the at least two high frequency pulses are bi-phasic.

15. The system of claim 12 wherein the frequency range is from 1.5 kHz to 50 kHz.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Apr 4, 2025
From: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT
To: NEVRO CORP.
Reel/Frame 070743/0001 →
PATENT SECURITY AGREEMENT Recorded Dec 1, 2023
From: NEVRO CORP.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT
Reel/Frame 065744/0302 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 7, 2023
From: ALATARIS, KONSTANTINOS; WALKER, ANDRE B.; PARKER, JON
To: NEVRO CORP.
Reel/Frame 065485/0763 →
Continuity (6)
Continuation 17552005 · Dec 15, 2021
Continuation 16670712 · Oct 31, 2019
Continuation 14292671 · May 30, 2014
Continuation 12765685 · Apr 22, 2010
Provisional Application 61171790 · Apr 22, 2009
Related Publication 20240024681A1 · Jan 25, 2024
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