Devices and methods for engaging indexed valve and pressurized canister assembly with collar and for linear actuation by plunger assembly into fluid communication with device for regulating drug delivery
A valve assembly including a housing and a valve, the valve being disposed within the housing, a first indexed member integral to the housing, the first indexed member adapted to be complementary to a second indexed member, and a radio frequency identification device adapted to communicate with a radio frequency receiver, the valve being configured to align with a canister, seal the canister and open in a single movement. A drug containment device having said valve assembly is also disclosed.
1. A valve assembly comprising:
a housing and a valve, the valve being disposed within the housing;
a first indexed member integral to the housing, the first indexed member adapted to be complementary to a second indexed member, wherein the first indexed member comprises a first arcuate opening and a second arcuate opening having at least one of different axial widths or misaligned mid-planes; and
a radio frequency identification device adapted to communicate with a radio frequency receiver,
wherein the valve is configured to align with a canister, seal the canister and open in a single movement.
2. The valve assembly of claim 1 , wherein the radio frequency identification device is adapted to communicate to the radio frequency receiver identifying information of the contents of a canister that is attachable to the valve.
3. The valve assembly of claim 1 , wherein the valve assembly is attachable to a canister comprising an active pharmaceutical ingredient including one of nitric oxide, with a concentration in the range of approximately 50 ppm to 10,000 ppm, carbon monoxide with a concentration in the range of approximately 500 ppm to 20,000 ppm, or, a chalcogenide compound and an inactive carrier gas comprising at least one of N 2 and O 2 .
4. The valve assembly of claim 3 , wherein the first and second indexed members are predeterminately adapted to indicate the identity and canister concentration of the active pharmaceutical ingredient.
5. The valve assembly of claim 1 , wherein the valve is linearly actuated.
6. A drug containment device comprising:
a valve assembly comprising a housing and a valve disposed within the housing, a first indexed member integral to the housing, the first indexed member adapted to be complementary to a second indexed member, wherein the first indexed member comprises a first arcuate opening and a second arcuate opening having at least one of different axial widths or misaligned mid-planes,
a canister in fluid communication with the valve assembly, the canister containing an active pharmaceutical ingredient and,
wherein the valve is configured to align with the canister, seal the canister and open in a single movement.
7. The drug containment device of claim 6 , further comprising a radio frequency identification device adapted to communicate to a radio frequency receiver identifying information of the active pharmaceutical ingredient.
8. The drug containment device of claim 6 , wherein the active pharmaceutical ingredient comprises one of nitric oxide, with a concentration in the range of approximately 50 ppm to 10,000 ppm, carbon monoxide with a concentration in the range of approximately 500 ppm to 20,000 ppm, or, a chalcogenide compound and the inactive carrier gas comprises at least one of N 2 and O 2 .
9. The drug containment device of claim 6 , wherein the first and second indexed members are predeterminately adapted to indicate the identity and concentration of an active pharmaceutical ingredient.