SARS-COV2 main protease inhibitors
The present disclosure relates to compounds of Formula I: and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.
1. A compound selected from
or a pharmaceutically acceptable salt thereof.
2. The compound of claim 1 , which is
or a pharmaceutically acceptable salt thereof.
3. The compound of claim 1 , which is
or a pharmaceutically acceptable salt thereof.
4. The compound of claim 1 , which is
or a pharmaceutically acceptable salt thereof.
5. The compound of claim 1 , which is
or a pharmaceutically acceptable salt thereof.
6. The compound of claim 1 , which is
or a pharmaceutically acceptable salt thereof.
7. The compound of claim 1 , which is
or a pharmaceutically acceptable salt thereof.
8. The compound of claim 1 , which is
or a pharmaceutically acceptable salt thereof.
9. The compound of claim 1 , which is
or a pharmaceutically acceptable salt thereof.
10. The compound of claim 1 , which is
or a pharmaceutically acceptable salt thereof.
11. The compound of claim 1 , which is
or a pharmaceutically acceptable salt thereof.
12. The compound of claim 1 , which is
or a pharmaceutically acceptable salt thereof.
13. The compound of claim 1 , which is
or a pharmaceutically acceptable salt thereof.
14. A compound selected from
15. The compound of claim 14 , which is
16. The compound of claim 14 , which is
17. The compound of claim 14 , which is
18. The compound of claim 14 , which is
19. The compound of claim 14 , which is
20. The compound of claim 14 , which is
21. The compound of claim 14 , which is
22. The compound of claim 14 , which is
23. The compound of claim 14 , which is
24. The compound of claim 14 , which is
25. The compound of claim 14 , which is
26. The compound of claim 14 , which is
27. A pharmaceutical composition comprising the compound of claim 1 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.
28. A pharmaceutical composition comprising the compound of claim 14 and a pharmaceutically acceptable excipient.