IP Library Granted Patent US 12,558,260
Granted Patent B2
US 12,558,260 · App. 18/393,287 · Granted Feb 24, 2026

Methods and systems for laser ophthalmic surgery that provide for iris exposures below a predetermined exposure limit

Inventors: Georg Schuele (Portola Valley, CA); David A. Dewey (Sunnyvale, CA); Javier G. Gonzalez (Palo Alto, CA); Alexander Vankov (Mountain View, CA)
Assignee: AMO DEVELOPMENT, LLC
A61F9/008A61B3/14A61B34/25A61F9/00825A61B2017/00154A61B2018/00601A61B2034/104A61B2090/0409A61B2090/049A61F2009/00853A61F2009/00872A61F2009/00878A61F2009/00887A61F2009/00897
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Quick Facts
Patent No.
US 12,558,260
App. No.
18/393,287
Granted
Feb 24, 2026
Kind
B2
Abstract

A laser surgical method for performing a corneal incision while maintaining iris exposure below a predetermined exposure limit includes: determining an initial iris exposure based on an initial treatment scan, determining whether the initial iris exposure is less than the predetermined exposure limit, generating a revised treatment scan comprising one or more treatment scan modifying elements when the initial iris exposure is greater than the predetermined exposure limit, and scanning the focal zone of a pulsed laser beam according to the revised treatment scan, thereby performing the corneal incision, wherein the one or more treatment scan modifying elements causes the iris exposure to be smaller than the predetermined exposure limit.

Claims (35)

1 . A system for cataract surgery on an eye of a patient, comprising:

a laser assembly for generating a pulsed laser treatment beam;

an imaging system configured for imaging an ocular tissue of the patient, the ocular tissue comprising corneal tissue;

an optical scanning system configured for positioning a focal zone of the treatment beam to targeted locations of the ocular tissue, the targeted locations including a location in the corneal tissue; and

a computer control system operatively coupled to the laser assembly, the imaging system, and the optical scanning system, and programmed to:

generate a simulated initial treatment scan pattern of the pulsed laser treatment beam corresponding to a predetermined corneal incision in the eye;

calculate a first time period over which the initial treatment scan pattern is carried out to deliver a first amount of laser energy on an iris tissue of the eye;

determine whether the first time period is greater than a predetermined minimum time period to deliver the first amount of laser energy on the iris tissue;

generate a simulated revised treatment scan pattern of the pulsed laser treatment beam for incising the corneal tissue which is different from the initial treatment scan pattern and which comprises one or more treatment scan modifying elements when the first time period is not greater than the predetermined minimum time period, wherein the one or more treatment scan modifying elements cause a calculated second time period over which the revised treatment scan pattern is carried out to be greater than the predetermined minimum time period; and

operate the optical scanning system and laser assembly to direct the laser treatment beam according to the revised treatment scan pattern, thereby performing the corneal incision.

2 . The system of claim 1 , wherein the one or more treatment scan modifying elements comprises an extension of scan paths so that at least a portion of turnarounds occur beyond an incision boundary, the extension of the scan paths being greater than 50% of a turnaround distance, and wherein a region corresponding to the portion of the scan paths extending beyond the respective incision boundary is not incisionable by the pulsed laser treatment beam.

3 . The system of claim 1 , wherein the one or more treatment scan modifying elements comprises an extension of the scan paths so that at least a portion of turnarounds are gated and extend beyond the incision boundary, the extension of the scan paths being greater than 50% of a turnaround distance.

4 . The system of claim 1 , wherein the one or more treatment scan modifying elements comprises a reoriented scan axis, and wherein the reoriented axis is reoriented along an axis corresponding to a largest distance between opposing incision boundaries.

5 . The system of claim 1 , wherein the one or more treatment scan modifying elements comprises a plurality of gated rows of a scan path inserted among active rows of the scan path in a fixed proportion, the fixed proportion being greater than or equal to one and less than or equal to 10.

6 . The system of claim 1 , wherein the computer control system is further programmed to perform a capsulotomy on the eye with the laser treatment beam.

7 . The system of claim 1 , wherein the corneal incision is an arcuate corneal incision, a sideport cataract incision, or a primary cataract incision.

8 . The system of claim 1 , wherein the initial scan pattern includes a set of parameters defining an arcuate corneal incision, a sideport cataract incision, or a primary cataract incision.

9 . The system of claim 8 , wherein the revised treatment scan pattern further includes a revised value for at least one of the set of parameters.

10 . A system for cataract surgery on an eye of a patient, comprising:

a laser assembly for generating a pulsed laser treatment beam;

an imaging system configured for imaging an ocular tissue of the patient, the ocular tissue comprising corneal tissue;

an optical scanning system configured for positioning a focal zone of the treatment beam to targeted locations of the ocular tissue, the targeted locations including a location in the corneal tissue;

a user interface for receiving input from a user;

a graphical user interface for providing information to the user; and

a computer control system operatively coupled to the laser assembly, the imaging system, the optical scanning system, the user interface and the graphical user interface, and programmed to:

receive a parameter set from a user via a user interface device;

generate a simulated initial treatment scan pattern of the laser treatment beam for incising the corneal tissue based on the parameter set received via the user interface device;

calculate an initial exposure level, which is an amount of laser energy per unit area of the laser treatment beam on an iris tissue of the eye caused by the initial treatment scan pattern;

determine whether the initial exposure level satisfies a predetermined safe exposure condition which is below an exposure that causes a minimal visible lesion in the iris tissue;

receive a revised parameter set from the user via the user interface device, the revised parameter set having at least one different parameter value than the initial parameter set,

wherein: (1) the parameter set defines an arcuate corneal incision, and the at least one different parameter value is selected from a group of values consisting of incision type, axis, optical zone, arc length, centering method, penetration type, depth units, uncut anterior, uncut posterior, and side cut angle, or (2) the parameter set defines a primary cataract incision, and the at least one different parameter value is selected from a group of values consisting of axis, limbus offset, width, length, uncut region, depth units, uncut anterior, uncut posterior, uncut central length, plane depth, and side cut angle, or (3) the parameter set defines a sideport cataract incision, and the at least one different parameter value is selected from a group of values consisting of number of incisions, axis, limbus offset, width, uncut type, uncut unit, anterior uncut length, posterior uncut length, and side cut angle;

generate a simulated revised treatment scan pattern of the laser treatment beam for incising the corneal tissue which is different from the initial treatment scan pattern and which is based on the revised parameter set received via the user interface;

calculate a revised exposure level, which is an amount of laser energy per unit area of the laser treatment beam on the iris tissue caused by the revised treatment scan pattern;

determine whether the revised exposure level satisfies the predetermined safe exposure condition; and

operate the optical scanning system and laser assembly to direct the laser treatment beam according to the revised treatment scan pattern if the revised exposure level satisfies the predetermined safe exposure condition, thereby performing the corneal incision.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 21, 2026
From: SCHUELE, GEORG; DEWEY, DAVID A.; GONZALEZ, JAVIER G.; VANKOV, ALEXANDER
To: OPTIMEDICA CORPORATION
Reel/Frame 073535/0248 →
MERGER Recorded Jan 21, 2026
From: OPTIMEDICA CORPORATION
To: AMO DEVELOPMENT, LLC
Reel/Frame 073535/0410 →
Continuity (4)
Continuation 17220877 · Apr 1, 2021
Division 15885616 · Jan 31, 2018
Provisional Application 62452911 · Jan 31, 2017
Related Publication 20240122756A1 · Apr 18, 2024
References Cited (100)
US 5049147A · Danon · 1991 [cited by applicant]
US 5720894A · Neev et al. · 1998 [cited by applicant]
US 5843070A · Cambier et al. · 1998 [cited by applicant]
US 5957915A · Trost · 1999 [cited by applicant]
US 5984916A · Lai · 1999 [cited by applicant]
US 6019472A · Koester et al. · 2000 [cited by applicant]
US 6210169B1 · Yavitz · 2001 [cited by applicant]
US 6454761B1 · Freedman · 2002 [cited by applicant]
US 7121665B2 · Su · 2006 [cited by examiner]
US 7655002B2 · Myers et al. · 2010 [cited by applicant]
US 7717907B2 · Ruiz et al. · 2010 [cited by applicant]
US 7801271B2 · Gertner et al. · 2010 [cited by applicant]
US 8262646B2 · Frey et al. · 2012 [cited by applicant]
US 8350183B2 · Vogel et al. · 2013 [cited by applicant]
US 8382745B2 · Naranjo-Tackman et al. · 2013 [cited by applicant]
US 8414564B2 · Goldshleger et al. · 2013 [cited by applicant]
US 8728061B2 · Donitzky · 2014 [cited by examiner]
US 9037217B1 · Peyman · 2015 [cited by applicant]
US 9411938B2 · Rathjen · 2016 [cited by applicant]
US 9445946B2 · Angeley et al. · 2016 [cited by applicant]
US 10485705B2 · Vankov · 2019 [cited by applicant]
US 10973683B2 · Schuele et al. · 2021 [cited by applicant]
US 20040243112A1 · Bendett et al. · 2004 [cited by applicant]
US 20050049584A1 · Homer · 2005 [cited by applicant]
US 20070091264A1 · Kahlen · 2007 [cited by applicant]
US 20070173793A1 · Rathjen · 2007 [cited by examiner]
US 20080033408A1 · Bueler et al. · 2008 [cited by applicant]
US 20080051773A1 · Ivanov et al. · 2008 [cited by applicant]
US 20080228176A1 · Triebel · 2008 [cited by examiner]
US 20080319430A1 · Zenzie · 2008 [cited by examiner]
US 20100256965A1 · Rathjen et al. · 2010 [cited by applicant]
US 20100305553A1 · Kittelmann et al. · 2010 [cited by applicant]
US 20100331830A1 · Bischoff et al. · 2010 [cited by applicant]
US 20110172649A1 · Schuele et al. · 2011 [cited by applicant]
US 20110196350A1 · Friedman et al. · 2011 [cited by applicant]
US 20110202114A1 · Kessel · 2011 [cited by examiner]
US 20110301524A1 · Bueler et al. · 2011 [cited by applicant]
US 20110319873A1 · Raksi et al. · 2011 [cited by applicant]
US 20110319875A1 · Loesel et al. · 2011 [cited by applicant]
US 20120016351A1 · Stobrawa et al. · 2012 [cited by applicant]
US 20120095349A1 · Peyman · 2012 [cited by applicant]
US 20120130357A1 · Triebel et al. · 2012 [cited by applicant]
US 20120150156A1 · Wolfel et al. · 2012 [cited by applicant]
US 20120172852A1 · Lubatschowski et al. · 2012 [cited by applicant]
US 20130085482A1 · Van Valen · 2013 [cited by examiner]
US 20130144277A1 · Rathjen et al. · 2013 [cited by applicant]
US 20130237972A1 · Raksi · 2013 [cited by applicant]
US 20130289544A1 · Triebel et al. · 2013 [cited by applicant]
US 20140111766A1 · Umekawa et al. · 2014 [cited by applicant]
US 20140114296A1 · Woodley et al. · 2014 [cited by applicant]
US 20140114297A1 · Woodley · 2014 [cited by examiner]
US 20140276680A1 · Dennison · 2014 [cited by examiner]
US 20140316389A1 · Schuele · 2014 [cited by examiner]
US 20140364840A1 · Donitzky et al. · 2014 [cited by applicant]
US 20150335477A1 · Schuele · 2015 [cited by examiner]
US 20160106588A1 · Srinivasan · 2016 [cited by examiner]
US 20160143775A1 · Rathjen · 2016 [cited by applicant]
US 20160166431A1 · Vogler et al. · 2016 [cited by applicant]
US 20160235588A1 · Hart · 2016 [cited by examiner]
US 20170000647A1 · Schuele · 2017 [cited by examiner]
US 20170000649A1 · Vankov · 2017 [cited by examiner]
US 20170007112A1 · Gonzalez · 2017 [cited by examiner]
US 20170011501A1 · Gonzalez · 2017 [cited by examiner]
US 20170035608A1 · Boxer Wachler · 2017 [cited by examiner]
US 20170326003A1 · Schuele · 2017 [cited by examiner]
US 20180103837A1 · Kurtz · 2018 [cited by examiner]
US 20180104099A1 · Kurtz et al. · 2018 [cited by applicant]
US 20180214305A1 · Schuele · 2018 [cited by examiner]
US 20200054489A1 · Thyzel · 2020 [cited by examiner]
EP 1810646A1 · 2007 [cited by applicant]
EP 1810647A1 · 2007 [cited by applicant]
EP 2236109A1 · 2010 [cited by applicant]
21 CFR, Part 1040—Performance Standards for Light-Emitting Products, in effect on Jan. 1, 2017 (see line 3 on p. 1), pp. 1-21. The document can be accessed using the link https://www.ecfr.gov/on/2017-01-01/title-21/chap… [cited by applicant]
“American National Standardfor Safe Use of Lasers,” Laser Institute of America, 2014, pp. 1-284. [cited by applicant]
Fankhauser F., et al., “Lasers in Ophthalmology. Basic, Diagnostic and Surgical Aspects, A Review”, Extract from the textbook, published in 2003 (see second page of D13); pp. 79-89. [cited by applicant]
“Group Safety Publication: Safety of Laser Products, Part 1: Equipment Classification and Requirements,” International Standard 60825-1, Second Edition, Mar. 2007, pp. 1-114. [cited by applicant]
Jean M., et al., “Image Analysis and Modeling in Ophthalmology,” CPC Press, Taylor Francis Group, 2014, pp. 265-291. [cited by applicant]
Konig K., “High-resolution Multiphoton Imaging and Nanosurgery of the Cornea using Femtosecond Laser Pulses,” In: Fankhauser F. and Kwasniewska S. (Editors), Lasers in Ophthalmology, Basic, Diagnostic and Surgical Aspec… [cited by applicant]
Krueger R.R., et al., “Textbook of Refractive Laser Assisted Cataract Surgery (ReLACS),” 2012. [cited by applicant]
“Laser safety,” Wikipedia, Jan. 2017, pp. 1-16. [cited by applicant]
Le Harzic R., et al., “Laser Safety Aspects for Refractive Eye Surgery with Femtosecond Laser Pulses,” Elsevier GmbH: Medical Laser Application, 2005, vol. 20, pp. 233-238. [cited by applicant]
Matthes R., “Guidelines on Limits of Exposure to Laser Radiation of Wavelengths between 180 nm and 1,000 μm,” Health Physics, 2013, vol. 105(3), pp. 271-295. [cited by applicant]
Ophthalmic Instruments—Fundamental Requirements and Test Methods, 2006, pp. 1-16. [cited by applicant]
Priority Application U.S. Appl. No. 62/452,911, filed Jan. 31, 2017. [cited by applicant]
Probst L.E., et al., “Femtosecond Cataract Surgery A Primer,” Chapter 2 (“LensAR Laser System”) and Chapter 3 (“LenSx Laser System”), Slack Incorporated, 2012, pp. S002-S037. [cited by applicant]
Rademacher S.E., et al., “Base-Level Management of Laser Radiation Protection Program,” Occupational and Environmental Health Directorate, Feb. 1992. [cited by applicant]
Roach W.P., et al., “Ultrashort Laser Pulse Bioeffects,” SPIE Milestone Series, 2003, pp. 639-647. [cited by applicant]
Sun H., et al., “Finite Element Model of the Temperature Increase in Excised Porcine Cadaver Iris during Direct Illumination by Femtosecond Laser Pulses,” Journal of Biomedical Optics, Jul. 2012, vol. 17(7), pp. 078001-… [cited by applicant]
Wang J., et al., “Safety of cornea and iris in ocular surgery with 355-nm lasers”; Journal of Biomedical Optics, Sep. 2015, vol. 20(9). [cited by applicant]
WIPO priority claim, received at WIPO on Feb. 15, 2018, pp. 1-108. [cited by applicant]
Zuclich J.A., et al., “Ocular Damage Induced by Ultrashort Laser Pulses,” Occupational and Environmental Health Directorate, Sep. 1993. [cited by applicant]
Zuclich J.A., et al., “Wavelength Dependence of Ocular Damage Thresholds in the near-IR to far-IR Transition Region: Proposed Revisions to MPEs,” Health Physics Society, 2007, vol. 92(1), pp. 58-66. [cited by applicant]
Fermann, M.E., et al., “Ultrafast Lasers Technology and Applications,” CRC Press, pp. 354-355, 2003. [cited by applicant]
Fermann, M.E., et al., “Ultrafast Lasers Technology and Applications,” CRC Press, pp. 699-765, 2003. [cited by applicant]
International Commission on Non-Ionizing Radiation Protection:, ICNIPR Guidelines—Revision of Guidelines on Limits of Exposure to Laser Radiation of Wavelengths Between 400 nm and 1.4 pm; published in Health Physics, vo… [cited by applicant]
Laser Institute of America: American National Standard for Safe Use of Lasers, published 2014. [cited by applicant]
South Dakota School of Mines Technology: “Laser safety manual”, created 15. Jun. 2007. [cited by applicant]
Wikipedia: Laser safety, revision Dec. 30, 2006. [cited by applicant]
Fachverband fur Strahlenschutz e.V.: Leitfaden “Laserstrahlung”, Publication date: Dec. 3, 2011 (see second page of D31 and also document D36). [cited by applicant]
Sliney, David H., “Ophthalmic Laser Safety”, Lasers in Ophthalmology Basic, Diagnostic and Surgical Aspects A Review, 14 pages, 2003. [cited by applicant]