IP Library Granted Patent US 12,616,668
Granted Patent B2
US 12,616,668 · App. 18/419,027 · Granted May 5, 2026

Nutritional supplement containing L-α-glycerophosphorylcholine

Inventors: Liangxi Li (Plantation, FL); John H. Owoc (Southwest Ranches, FL)
Assignee: Energy Beverages LLC
A61K31/14A23L2/52A23L33/30A61K9/0095A61K31/197A61K31/522A61K31/661A61K36/74
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Quick Facts
Patent No.
US 12,616,668
App. No.
18/419,027
Granted
May 5, 2026
Kind
B2
Abstract

A nutritional supplement contains 50% to 80% by weight of trimethylglycine; 5% to 30% by weight of L-α-glycerophosphorylcholine; 5% to 15% by weight of caffeine; and 5% to 10% by weight of an ingredient selected from the group consisting of an L-amino acid, creatyl-L-leucine, Corynanthe yohimbe bark extract, theacrine, and mixtures thereof. The nutritional supplement is useful for enhancing energy, mental acuity, cognitive performance, and reaction time in a subject in need thereof.

Claims (24)

1 . A nutritional supplement composition, comprising:

a. 60% to 75% by weight of trimethylglycine;

b. 10% to 20% by weight of L-α-glycerophosphorylcholine or a precursor thereof, wherein the precursor is phosphatidylethanolamine, phosphatidylcholine, or citicoline;

c. 5% to 15% by weight of caffeine; and

d. 5% to 10% by weight of an ingredient selected from the group consisting of an L-amino acid, creatyl-L-leucine, Corynanthe yohimbe bark extract, theacrine, and mixtures thereof; and

a carrier.

2 . The composition of claim 1 , wherein the carrier is an aqueous carrier or a solid carrier.

3 . The composition of claim 2 , wherein the composition is a beverage.

4 . The composition of claim 3 , wherein the carrier is an aqueous carrier comprising electrolyte salts.

5 . The composition of claim 1 , wherein the ingredient contains creatyl-L-leucine.

6 . The composition of claim 1 , wherein the ingredient is an L-amino acid selected from the group consisting of methionine, asparagine, glutamine, aspartic acid, glutamic acid, theanineand combinations thereof.

7 . The composition of claim 6 , wherein the L-amino acid is L-theanine.

8 . The composition of claim 1 , wherein the ingredient is an L-amino acid selected from the group consisting of an N-alkyl derivative of asparagine, an N-alkyl derivative of glutamine, an alkyl ester of aspartic acid, an alkyl ester of glutamic acid, and combinations thereof.

9 . The composition of claim 8 , wherein the ingredient contains N 5 -ethyl-Lglutamine.

10 . A method of enhancing pattern recognition skills and reaction time in a subject in need thereof, comprising administering an effective amount of the composition of claim 1 to the subject.

11 . A beverage, comprising:

a. 5% to 80% by weight of trimethylglycine;

b. 5% to 30% by weight of L-α-glycerophosphorylcholine;

c. 5% to 15% by weight of caffeine; and

d. 5% to 10% by weight of an ingredient selected from the group consisting of an L-amino acid, creatyl-L-leucine, Corynanthe yohimbe bark extract, theacrine, and mixtures thereof; and

e. an aqueous carrier;

wherein the weight ratio of L-α-glycerophosphorylcholine to caffeine is 1:1 to 2:1.

12 . The beverage of claim 11 , wherein the aqueous carrier comprises an electrolyte salt.

13 . A method of enhancing pattern recognition skills and reaction time in a subject in need thereof, comprising administering an effective amount of the beverage of claim 11 to the subject.

Continuity (3)
Continuation 17346621 · Jun 14, 2021
Provisional Application 63038403 · Jun 12, 2020
Related Publication 20240307324A1 · Sep 19, 2024
References Cited (6)
US 11877989B2 · Li · 2024 [cited by examiner]
US 20180042274A1 · Bratt · 2018 [cited by examiner]
US 20190133147A1 · Ranelli · 2019 [cited by examiner]
US 20210169891A1 · Lelah · 2021 [cited by examiner]
Tinsley et al. Journal of the International Society of Sports Nutrition, 2017, 14:46, pp. 1-11 (Year: 2017). [cited by examiner]
Hoffman et al. Journal of the International Society of Sports Nutrition, 2010, 7:39, pp. 1-8 (Year: 2010). [cited by examiner]