THERMAL THROMBECTOMY SYSTEMS AND METHODS
This disclosure relates to thermal thrombectomy systems and methods. The thermal thrombectomy systems can apply heat to a thrombus, softening and/or melting the thrombus, which can include one or more proteins and/or biopolymers of the thrombus, to ease removal. The thermal thrombectomy systems can include a heated wire that can be navigated to the thrombus. The distal portion of the wire can apply heat to the thrombus while the proximal portion may be insulated. The heated wire can include coils and or other features to facilitate engagement with the thrombus.
1 . A thermal device configured to apply heat to a thrombus, the thermal device comprising:
an outer tube comprising a distal portion;
a heated element disposed at the distal portion of the outer tube; and
one or more conduits configured to apply an electrical current to the heated element to raise a temperature of the heated element to apply heat to a thrombus.
2 . The thermal device of claim 1 , further comprising an inner tube disposed within the outer tube that is configured to receive a guide wire, wherein the thermal device is configured to be advanced over the guide wire.
3 . The thermal device of claim 1 , wherein the heated element comprises a loop.
4 . The thermal device of claim 3 , wherein the loop comprises a nickel titanium alloy.
5 . The thermal device of claim 3 , wherein the loop comprises a tube.
6 . The thermal device of claim 5 , wherein the loop comprises a hollow lumen, and the thermal device further comprising a temperature sensor disposed within the hollow lumen.
7 . The thermal device of claim 6 , further comprising a controller configured to modulate the electrical current applied to the heated element based on a sensed temperature by the temperature sensor.
8 . The thermal device of claim 1 , further comprising a temperature sensor.
9 . The thermal device of claim 1 , further comprising an electrode to sense leaked current.
10 . The thermal device of claim 9 , wherein the electrode is a marker for visualization.
11 . The thermal device of claim 1 , further comprising an expandable device configured to be expanded proximally of the thrombus.
12 . The thermal device of claim 11 , wherein the expandable device comprises a balloon.
13 . The thermal device of claim 11 , wherein the expandable device comprises a lumen through which the outer tube is configured to be advanced.
14 . A thermal thrombectomy device configured to apply heat to a thrombus, the thermal thrombectomy device comprising:
an expandable assembly comprising an expandable device, the expandable device configured to be expanded proximally of a thrombus; and
a thermal assembly comprising a heated element, the thermal assembly configured to be advanced distally over a guide wire and out of the expandable assembly to apply heat to the thrombus with the heated element.
15 . The thermal thrombectomy device of claim 14 , wherein the thermal assembly further comprises one or more conduits configured to apply an electrical current to the heated element to raise a temperature of the heated element.
16 . The thermal thrombectomy device of claim 14 , wherein the expandable device is a balloon.
17 . The thermal thrombectomy device of claim 14 , wherein the heated element comprises a loop.
18 . The thermal thrombectomy device of claim 17 , wherein the loop comprises a tube.
19 . The thermal thrombectomy device of claim 18 , wherein the loop comprises a hollow lumen, and the thermal thrombectomy device further comprises a temperature sensor disposed within the hollow lumen.
20 . The thermal thrombectomy device of claim 19 , further comprising a controller configured to modulate electrical current applied to the heated element based on a sensed temperature by the temperature sensor.
21 . The thermal thrombectomy device of claim 14 , further comprising a temperature sensor.
22 . The thermal thrombectomy device of claim 14 , further comprising an electrode to sense leaked current.
23 . A method of crossing a thrombus, the method comprising:
advancing a thermal assembly over a guide wire to a thrombus; and
applying an electrical current to a heated element of the thermal assembly to heat the thrombus.
24 . The method of claim 23 , further comprising advancing an expandable device comprising a balloon over the guide wire to proximate the thrombus and expanding the balloon.