Patent Application
Utility
App. No. 18/427,072
· Confirmation No. 1023
OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION
Inventors:
Muthiah MANOHARAN, Jayaprakash K. NAIR, Pachamuthu KANDASAMY, Shigeo MATSUDA, Alexander V. KELIN, Muthusamy JAYARAMAN, Kallanthottathil G. RAJEEV
Applicant:
ALNYLAM PHARMACEUTICALS, INC.
Docketed New Case - Ready for Examination
View Publication ↗
|
⬇ PDF
|
Code | Description | Pages | ||
|---|---|---|---|---|---|
| 2026-07-23 | AMSB |
Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE) | — | View | |
| 2026-07-23 | RCEX |
Request for Continued Examination (RCE) | 3 | View | |
| 2026-07-23 | AMSB |
Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE) | 1 | View | |
| 2026-07-23 | REM |
Applicant Arguments/Remarks Made in an Amendment | 4 | View | |
| 2026-07-23 | XT/ |
Extension of Time | 2 | View | |
| 2026-07-23 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2026-07-23 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2026-07-16 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 5 | View | |
| 2026-07-16 | FOR |
Foreign Reference | 87 | View | |
| 2026-07-16 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2026-07-16 | FOR |
Foreign Reference | 190 | View | |
| 2026-07-16 | TRAN.LET |
Transmittal Letter | 2 | View | |
| 2026-07-16 | FOR |
Foreign Reference | 234 | View | |
| 2026-07-16 | FOR |
Foreign Reference | 313 | View | |
| 2026-07-16 | FOR |
Foreign Reference | 100 | View | |
| 2026-07-16 | FOR |
Foreign Reference | 18 | View | |
| 2026-07-16 | FOR |
Foreign Reference | 740 | View | |
| 2026-07-16 | FOR |
Foreign Reference | 193 | View | |
| 2026-02-23 | CTFR |
Final Rejection | 25 | View | |
| 2026-02-23 | SRFW |
Search information including classification, databases and other search related notes | 2 | View | |
| 2026-02-23 | SRNT |
Examiner's search strategy and results | 13 | View | |
| 2026-02-23 | SRNT |
Examiner's search strategy and results | 2 | View | |
| 2026-02-23 | 1449 |
List of References cited by applicant and considered by examiner | 5 | View | |
| 2026-02-17 | FOR |
Foreign Reference | 194 | View | |
| 2026-02-17 | FOR |
Foreign Reference | 464 | View | |
| 2026-02-17 | FOR |
Foreign Reference | 512 | View | |
| 2026-02-17 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 5 | View | |
| 2026-02-17 | FOR |
Foreign Reference | 423 | View | |
| 2026-02-17 | TRAN.LET |
Transmittal Letter | 2 | View | |
| 2026-02-17 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2026-02-17 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2025-12-23 | A... |
Amendment/Request for Reconsideration-After Non-Final Rejection | — | View | |
| 2025-12-23 | A... |
Amendment/Request for Reconsideration-After Non-Final Rejection | 1 | View | |
| 2025-12-23 | REM |
Applicant Arguments/Remarks Made in an Amendment | 5 | View | |
| 2025-12-23 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2025-10-01 | CTNF |
Non-Final Rejection | 21 | View | |
| 2025-10-01 | 892 |
List of references cited by examiner | 1 | View | |
| 2025-10-01 | SRFW |
Search information including classification, databases and other search related notes | 2 | View | |
| 2025-10-01 | FOR |
Foreign Reference | 148 | View | |
| 2025-10-01 | BIB |
Bibliographic Data Sheet | 2 | View | |
| 2025-10-01 | SRNT |
Examiner's search strategy and results | 13 | View | |
| 2025-10-01 | 1449 |
List of References cited by applicant and considered by examiner | 6 | View | |
| 2025-10-01 | SRNT |
Examiner's search strategy and results | 3 | View | |
| 2025-10-01 | SRNT |
Examiner's search strategy and results | 9 | View | |
| 2025-08-01 | ELC. |
Response to Election / Restriction Filed | — | View | |
| 2025-08-01 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2025-08-01 | ELC. |
Response to Election / Restriction Filed | 1 | View | |
| 2025-08-01 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2025-06-04 | CTRS |
Requirement for Restriction/Election | 6 | View | |
| 2025-03-06 | NTC.PUB |
Notice of Publication | 1 | View | |
| 2024-09-23 | WCLM |
Claims Worksheet (PTO-2022) | 1 | View | |
| 2024-09-23 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2024-09-23 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2024-09-23 | R48.REQ.G |
Acceptance of Request under Rule 48 to correct inventorship or name | 1 | View | |
| 2024-09-23 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2024-09-16 | A.PE |
Preliminary Amendment | — | View | |
| 2024-09-16 | ADS |
Application Data Sheet | 9 | View | |
| 2024-09-16 | PEFR |
Applicant Response to Pre-Exam Formalities Notice | 2 | View | |
| 2024-09-16 | R48.REQ |
Request under Rule 48 correcting inventorship | 3 | View | |
| 2024-09-16 | XT/ |
Extension of Time | 2 | View | |
| 2024-09-16 | A.PE |
Preliminary Amendment | 1 | View | |
| 2024-09-16 | CLM |
Claims | 14 | View | |
| 2024-09-16 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2024-09-16 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2024-09-16 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2024-02-16 | NTC.MISS.PRT |
Notice to File Missing Parts | 3 | View | |
| 2024-02-16 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2024-02-16 | WCLM |
Claims Worksheet (PTO-2022) | 1 | View | |
| 2024-02-16 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2024-02-16 | WELCOME.LET |
Welcome Letter from USPTO Director and Deputy Director | 1 | View | |
| 2024-01-30 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2024-01-30 | SPEC |
Specification | 302 | View | |
| 2024-01-30 | APP.TEXT |
Application body structured text document | — | View | |
| 2024-01-30 | A.PE |
Preliminary Amendment | — | View | |
| 2024-01-30 | CLM |
Claims | 29 | View | |
| 2024-01-30 | ABST |
Abstract | 1 | View | |
| 2024-01-30 | A.PE |
Preliminary Amendment | 1 | View | |
| 2024-01-30 | SPEC |
Specification | 1 | View | |
| 2024-01-30 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2024-01-30 | ADS |
Application Data Sheet | 10 | View | |
| 2024-01-30 | TRNA |
Transmittal of New Application | 2 | View | |
| 2024-01-30 | OATH |
Oath or Declaration filed | 9 | View | |
| 2024-01-30 | PA.. |
Power of Attorney | 1 | View | |
| 2024-01-30 | DRW |
Drawings-only black and white line drawings | 14 | View | |
| 2024-01-30 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2024-01-30 | TRAN.LET |
Transmittal Letter | 2 | View | |
| 2024-01-30 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 6 | View | |
| 2024-01-30 | SPEC |
Specification | 224 | View |
Inventors
Muthiah MANOHARAN
CAMBRIDGE, MA
Jayaprakash K. NAIR
CAMBRIDGE, MA
Pachamuthu KANDASAMY
CAMBRIDGE, MA
Shigeo MATSUDA
CAMBRIDGE, MA
Alexander V. KELIN
CAMBRIDGE, MA
Muthusamy JAYARAMAN
CAMBRIDGE, MA
Kallanthottathil G. RAJEEV
CAMBRIDGE, MA
Attorneys & Agents of Record
Classification
USPC
536/24.5
C07H21/00
C12N15/113
A61K47/549
A61P43/00
A61P1/16
C12N15/111
C12N2310/14
C12N2310/351
C12N2320/30
C12N2320/32
C12N2330/30
Prosecution
- Examiner
- VANHORN, ABIGAIL LOUISE
- Art Unit
- 1636
- Customer No.
- 13920
- Docket No.
- 135399-04104
- Confirmation No.
- 1023
Publication
- Pub. No.
- US20250075208A1
- Pub. Date
- 2025-03-06
Parent
is a Continuation of
→
App. 17/062,422
· US 12,173,288
Filed 2020-10-02
· Patented Case
Parent
is a Continuation of
→
App. 14/901,945
· US 10,808,246
Filed 2015-12-29
· Patented Case
Parent
PCT
is a National Stage Entry of
→
PCT/US2014/046425
Filed 2014-07-11
· Docketed New Case - Ready for Examination
Parent
Claims priority from a provisional application
→
App. 61/845,279
Filed 2013-07-11
· Provisional Application Expired
SECURITY INTEREST
Recorded 2025-10-01
from
KANDASAMY, PACHAMUTHU,
MANOHARAN, MUTHIAH,
MATSUDA, SHIGEO,
NAIR, JAYAPRAKASH K,
RAJEEV, KALLANTHOTTATHIL G,
KELIN, ALEXANDER V,
JAYARAMAN, MUTHUSAMY
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded 2024-01-30
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this application's details
Quick Facts
- App. No.
- 18/427,072
- Filed
- 2024-01-30
- Pub. No.
- US20250075208A1
- Examiner
- VANHORN, ABIGAIL LOUISE
- Art Unit
- 1636
External Links