SYSTEM FOR BLOOD GLUCOSE MEASUREMENT BASED ON RAMAN SPECTROSCOPY
Blood glucose level measurement includes a light source configured to irradiate light to a subject; a monochrome part configured to separate wavelength components of the light that is reflected and scattered from the subject; a light receiver configured to receive the light transmitted via the monochrome part and to generate electrical signals based on the received light; and a processor configured to extract information on the blood glucose level of the subject based on a frequency shift of the light due to the Raman effect.
1 . A non-transitory computer readable medium containing program instructions executed by a processor or controller, the program instructions when executed by the processor or controller configured to:
cause a light source to irradiate light to a subject;
receive, from a light receiver, electrical signals representative of a Raman spectrum of the light, which is reflected and scattered from the subject, and wavelength components of which are separated by using a monochrome part; and
determine a blood glucose level of the subject based on the Raman spectrum, wherein the blood glucose level is determined based on ratios of areas of (a) a peak at about 1450 cm −1 , (b) a peak at about 166 0 cm −1 , and (c) a peak at about 1125 cm −1 in the Raman spectrum.
2 . The non-transitory computer readable medium of claim 1 , wherein, for (a) the peak at about 1450 cm −1 , the area is obtained in a range between about 1415 cm −1 and about 1480 cm −1 , which corresponds to proteins.
3 . The non-transitory computer readable medium of claim 1 , wherein, for (b) the peak at about 1660 cm −1 , the area is obtained in a range between about 1630 cm −1 to about 1685 cm −1 , which corresponds to fats.
4 . The non-transitory computer readable medium of claim 1 , wherein, for (c) the peak at about 1125 cm −1 , the area is obtained by summing areas in three ranges (c-i) between about 1089cm −1 and about 1160 cm-1, (c-ii) between about 1115 cm −1 and about 1140 cm −1 , and (c-iii) between about 1120 cm −1 and about 1130 cm −1 , which correspond to glucose.