IP Library Granted Patent US 12,484,813
Granted Patent B2
US 12,484,813 · App. 18/427,955 · Granted Dec 2, 2025

Raman spectroscopy apparatus for blood glucose measurement comprising linear variable filter

Inventors: Miyeon Jue (Seoul, KR); Young Kyu Kim (Seoul, KR); Aram Hong (Seoul, KR)
Assignee: Apollon Inc.
A61B5/14532A61B5/0002A61B5/1455G01N21/65G01N33/49A61B5/6801G01N2201/061G01N2201/127
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Quick Facts
Patent No.
US 12,484,813
App. No.
18/427,955
Granted
Dec 2, 2025
Kind
B2
Abstract

Blood glucose level measurement includes a light source configured to irradiate light to a subject; a monochrome part configured to separate wavelength components of the light that is reflected and scattered from the subject; a light receiver configured to receive the light transmitted via the monochrome part and to generate electrical signals based on the received light; and a processor configured to extract information on the blood glucose level of the subject based on a frequency shift of the light due to the Raman effect.

Claims (15)

1 . An apparatus for measuring blood glucose level, comprising:

a light source configured to irradiate light to a subject;

a linear variable filter that filters the light reflected and scattered by the subject, wherein the linear variable filter is configured such that different areas thereof pass different wavelength components of light; and

a light receiver configured to receive the light transmitted through the linear variable filter and to generate electrical signals representative of a Raman spectrum of the light reflected and scattered from the subject; and

a processor configured to extract information on the blood glucose level of the subject based on the Raman spectrum,

wherein the linear variable filter includes a 915 nm filter area to allow a 1125 cm −1 peak in the Raman spectrum to pass and the processor configured to extract the information on the blood glucose level based on each of at least three areas of peaks (i) between 1089 cm −1 and 1160 cm −1 , (ii) between 1115 cm −1 and 1140 cm −1 , and (iii) between 1120 cm −1 and 1130 cm −1 .

2 . The apparatus of claim 1 , further comprising:

a rotation member coupled to the linear variable filter; and

a filter feeding member coupled to the rotation member,

wherein the filter feeding member is configured to rotate the rotation member, and

wherein rotation of the rotation member is configured to move the linear variable filter to allow different areas of the linear variable filter to be disposed in front of the light receiver sequentially.

3 . The apparatus of claim 1 , wherein the linear variable filter is further configured to transmit wavelength components between 1415 cm −1 and 1480 cm −1 .

4 . The apparatus of claim 1 , wherein the linear variable filter is further configured to transmit wavelength components between 1630 cm −1 to 1685 cm −1 .

5 . The apparatus of claim 1 , wherein the light source irradiates a near-infrared (NIR) ray or a mid-infrared (MIR) ray.

6 . The apparatus of claim 1 , wherein the light receiver is implemented as a charge coupled device (CCD).

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 5, 2024
From: JUE, MIYEON; KIM, YOUNG KYU; HONG, ARAM
To: APOLLON INC.
Reel/Frame 066646/0125 →
Priority Claims (1)
KR 10-2023-0069417 · May 30, 2023 · national
Continuity (2)
Continuation 18455492 · Aug 24, 2023
Related Publication 20240398283A1 · Dec 5, 2024
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