IP Library Granted Patent US 12,310,951
Granted Patent B2
US 12,310,951 · App. 18/440,652 · Granted May 27, 2025

Methods of administering anti-fibrotic therapy

Inventors: Lin Pan (San Francisco, CA); Dorothy Sze-Wing Cheung (San Francisco, CA); Jeffrey Mark Harris (San Francisco, CA); Indiana Strombom (San Francisco, CA)
Assignee: Genentech, Inc.
A61K31/437A61K31/4439
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Quick Facts
Patent No.
US 12,310,951
App. No.
18/440,652
Granted
May 27, 2025
Kind
B2
Abstract

The present disclosure relates to methods of administering Compound I for treating fibrotic disorders, inflammatory disorders or autoimmune disorders.

Claims (2)

1. A method of administering Compound I to treat a subject suffering from a fibrotic disorder said method comprising

increasing the maximal plasma concentration (C max ) or the extent of absorption (AUC 0-t or AUC 0-∞ ) of Compound I wherein the C max or AUC of Compound I with food is increased compared to the C max or AUC of the same amount of Compound I administered without food.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 25, 2024
From: INTERMUNE, INC.
To: GENENTECH, INC.
Reel/Frame 068698/0708 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 14, 2024
From: PAN, LIN; CHEUNG, DOROTHY SZE-WING; HARRIS, JEFFREY MARK; STROMBOM, INDIANA
To: GENENTECH, INC.
Reel/Frame 066457/0911 →