FENESTRATED VASCULAR AORTIC REPAIR STENT, SYSTEMS, AND METHODS
Endovascular prostheses used to treat diseased blood vessels, such as arteries, are disclosed. In some embodiments, an endovascular prosthesis is configured to be implanted within a diseased blood vessel adjacent a diseased section. The endovascular prosthesis may include a fenestration tube through which a guidewire extends in a sealed configuration. The fenestration tube can be selectively openable and configured to sealingly receive an expandable endovascular prosthesis that extends into a side branch vessel of the diseased blood vessel.
1 . A method of implanting a fenestrated endovascular prosthesis, the method comprising:
providing a fenestrated endovascular prosthesis comprising a guidewire extending through a fenestration;
deploying the fenestrated endovascular prosthesis at a treatment site within a blood vessel; and
un-sealing a seal region of a lumen in communication with the fenestration to transition the lumen from a sealed configuration to an open configuration, wherein:
after un-sealing the seal region, the lumen is in fluid communication with a bore of the fenestrated endovascular prosthesis and an exterior of the fenestrated endovascular prosthesis.
2 . The method of claim 1 , further comprising deploying a secondary endovascular prosthesis within the lumen and within a branch vessel of the blood vessel, wherein the secondary endovascular prosthesis is in fluid communication with the bore of the endovascular prosthesis and with the branch vessel.
3 . The method of claim 2 , further comprising replacing the guidewire with a steerable guidewire, wherein the steerable guidewire is advanced into the branch vessel, and wherein the secondary endovascular prosthesis is deployed after advancing the secondary endovascular prosthesis along the steerable guidewire.
4 . The method of claim 1 , wherein un-sealing the seal region comprises advancing a tapered fenestration dilator along the guidewire into the seal region.
5 . The method of claim 1 , further comprising radially expanding the secondary endovascular prosthesis to form a seal between an exterior surface of the secondary endovascular prosthesis and an interior surface of the lumen.
6 . The method of claim 2 , wherein the secondary endovascular prosthesis is positioned with a proximal end of the secondary endovascular prosthesis disposed proximal to a proximal end of the lumen and a distal end of the secondary endovascular prosthesis disposed in the branch vessel prior to the secondary endovascular prosthesis being deployed.
7 . The method of claim 2 , wherein un-sealing the seal region comprises:
advancing a fenestration balloon dilator along the guidewire into the seal region; and
expanding the fenestration balloon dilator to un-seal the seal region.
8 . A method of bypassing a diseased segment of a vessel, the method comprising:
deploying a primary endovascular prosthesis within a primary vessel, wherein:
a proximal portion of the primary endovascular prosthesis sealingly engages a non-diseased portion of the primary vessel;
blood flow to a first branch vessel of the primary vessel is restricted by the primary endovascular prosthesis;
a first guidewire extends through a first fenestration disposed in a wall of the primary endovascular prosthesis; and
a second guidewire extends through a second fenestration disposed in the wall of the primary endovascular prosthesis;
opening a seal region of a lumen of the first fenestration such that the lumen is in fluid communication with a bore of the primary endovascular prosthesis,
deploying a secondary endovascular prosthesis in the lumen such that the secondary endovascular prosthesis is in fluid communication with the bore of the primary endovascular prosthesis and the first branch vessel.
9 . The method of claim 8 , wherein the seal region is opened by advancing a dilator along the first guidewire from a distal end of the first guidewire.
10 . The method of claim 9 , wherein the secondary endovascular prosthesis is advanced along the first guidewire from a proximal end of the first guidewire.
11 . The method of claim 9 , wherein:
the first guidewire is used to advance a steerable guidewire from a proximal access site through the lumen;
the method further comprises steering the steerable guidewire into the first branch vessel; and
the secondary endovascular prosthesis is advanced along the steerable guidewire from a proximal end of the steerable guidewire.
12 . The method of claim 8 , wherein the secondary endovascular prosthesis is positioned extending from proximal a proximal end of the first fenestration distally into the first branch vessel.
13 . The method of claim 8 , further comprising radially expanding the secondary endovascular prosthesis to form a seal between an exterior surface of the secondary endovascular prosthesis and an interior surface of the lumen.
14 . A method comprising:
advancing a guidewire from an insertion site, through a treatment site, to an extraction site; and
advancing a fenestrated endovascular prosthesis to the treatment site, wherein:
the guidewire extends through a fenestration tube of the fenestrated endovascular prosthesis between a bore of the fenestrated endovascular prosthesis and an exterior of the fenestrated endovascular prosthesis; and
the fenestration tube comprises a seal region encircling the guidewire when the fenestration tube is in a sealed configuration.
15 . The method of claim 14 , further comprising advancing a dilator along the guidewire to un-seal the seal region such that the fenestration tube is in an open configuration.
16 . The method of claim 15 , further comprising deploying a secondary endovascular prosthesis in the fenestration tube after the fenestration tube is in the open configuration.
17 . The method of claim 14 , further comprising:
advancing a steerable instrument through the fenestration tube into a branch vessel adjacent the treatment site;
advancing a secondary endovascular prosthesis along the steerable instrument into the fenestration tube and the branch vessel; and
deploying the secondary endovascular prosthesis such that the secondary endovascular prosthesis is sealed to the fenestration tube and the branch vessel.
18 . The method of claim 14 , further comprising:
unsealing the fenestration tube to an open configuration;
advancing a secondary endovascular prosthesis into the fenestration tube in the open configuration such that a proximal end of the secondary endovascular prosthesis extends into the bore of the fenestrated endovascular prosthesis proximal to a proximal end of the fenestration tube; and
sealingly deploying the secondary endovascular prosthesis in the fenestration tube.
19 . The method of claim 18 , further comprising determining relative positions of the secondary endovascular prosthesis and the fenestration tube using radioscopy prior to sealingly deploying the secondary endovascular prosthesis.
20 . The method of claim 14 , further comprising removing the guidewire from the fenestration tube, wherein blood flow out of the fenestrated endovascular prosthesis through the fenestration tube is restricted by the seal region after the guidewire is removed.